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The surprising science-backed ingredient in this $198 anti-aging serum
DefenAge 8-in-1 BioSerum costs $198 and uses Age-Repair Defensins®. Here's the science behind the anti-aging serum and what research shows.
The Best Time to Fix Your Business Is When Things Are Going Well by Nathan Tayloe
There's a pattern I've noticed working with growing businesses over the years. Conversations about what needs to change rarely happen when things are going well. They tend to happen when growth slows, a competitor starts winning business, or something that used to work stops producing the same results. By then, the decisions are often harder, more expensive, and more urgent than they needed to be. It's understandable. When revenue is growing, customers are coming in, and employees are busy, there's little incentive to question what's working. Leaders have plenty to manage without creating new challenges for themselves. Running my own business has taught me that it's easy to get caught up in what's happening today and put off improvements you know will matter tomorrow. Those periods of success may actually be the best opportunity a business has to make meaningful improvements. When Success Makes Change Less Urgent Most businesses have things they know could be better. The challenge is finding a compelling reason to address them when everything appears to be working. Maybe the company has outgrown its original positioning. Perhaps internal processes haven't kept pace with growth, or the customer experience has become inconsistent as the organization has expanded. These issues don't necessarily prevent a business from growing. Strong demand can make them easier to overlook, especially when teams are focused on keeping up with the work already coming in. Over time, small inefficiencies become accepted ways of operating. Outdated processes remain in place because they've always worked well enough, and opportunities to improve get pushed aside in favor of more immediate demands. The business continues moving forward, but some of the things supporting that growth aren't getting stronger along with it. The Advantage of Acting Early When a business is performing well, leadership has something valuable: options. There's more flexibility to invest, experiment, develop people, and make thoughtful decisions without the pressure of an immediate problem that needs solving. Compare that with trying to make the same changes when revenue is declining, or the market has shifted. Investments become harder to justify, timelines get compressed, and decisions that could have been made strategically become urgent responses to circumstances. I've seen businesses postpone improvements for years because there was never a particularly good time to address them. Eventually, circumstances decide for them, often when they have fewer resources and less flexibility to respond. Growth Changes What a Business Needs This is especially relevant in a growing market like Wilmington, where new businesses, new residents, and continued investment are creating opportunities across the region. As organizations grow, the expectations placed on them change. Customers expect greater consistency, employees need clearer processes and opportunities, and leadership has to make decisions that support a larger, more complex business. What worked when a company was smaller may still work today, but that doesn't necessarily mean it will support where the organization wants to go next. Sometimes the most valuable improvements are the ones that prepare a business for demands it hasn't experienced yet. That might mean: Strengthening internal processes before they become bottlenecks Developing leaders before the organization depends on them Improving the customer experience before inconsistencies affect retention Revisiting positioning before the market outgrows the company's story None of these changes requires a crisis. They require recognizing that a growing business needs to keep evolving, even when current performance gives leadership little reason to worry. Use the Good Years Wisely Successful businesses don't need to constantly reinvent themselves. There's value in knowing what works and having the discipline to build on it. There's also value in occasionally asking whether the business is as strong as its current performance suggests. Are there problems we've learned to work around instead of solving? Are we still operating the way we did several years ago, even though the business has changed? What would we improve today if we weren't waiting for something to go wrong? Success creates the freedom to ask those questions and act on the answers. The businesses that make the most of that opportunity are often better prepared for whatever comes next. The strongest businesses don't need a crisis to recognize an opportunity to improve. They use the good years to prepare for the years ahead. — Learn more about how we help organizations strengthen their positioning, align their strategy, and prepare for what's next at tayloegray.com, or reach out directly at nathan@tayloegray.com.
Apple Alerts Stores to iPhone Duo's Display Cracking Issue
In a memo shared with Apple Stores and Apple Authorized Service Providers this week, and later obtained by MacRumors, Apple provided technicians with guidance on how to diagnose and address the iPhone Duo's inner display cracking issue. If a customer reports the issue, Apple advised technicians to inspect the iPhone Duo and repair or replace it in accordance with their standard procedures.
Health department tests Winnebago County home for lead after child's blood test
Winnebago County offers funding to renovate homes to remove lead
Health Department releases food inspection reports for week of Oct. 18
Scores for the recent Health Department food inspection ranged from 82-100.
Liberty High Handles Business In Road Win at Indianola in 5A Postseason Opener
Ryan Murken Your Prep Sports INDIANOLA – Mitch Wieland isn’t the first coach to get a good feeling about an upcoming game based on what has happened at practice. While Wieland liked how his Liberty High team prepared for its playoff opener on Friday it was something else the first-year head coach saw this week […]
Sir Patrick Stewart, Stage Veteran and Actor Known for Star Trek and X-Men, Dead at 86
It’s been a heavy week, but nothing could have prepared the entertainment world for a loss quite like this. With
Commissioner Brett Yormark leaving Big 12 after January
Big 12 Commissioner Brett Yormark is leaving the conference, a decision he made as he prepares to take another job outside of college sports.
Russell Wilson And Ciara Cover Town & Country
The couple reveals the Christmas rule helping their four children stay humble as they prepare to welcome "Baby Cinco."
Florida education chief defends science plan
Education Commissioner Henry Mack pushed back Tuesday against criticism that Florida is de-emphasizing evolution in its new plan for teaching science, insisting the state is still covering a subject he agreed was a bedrock of biological science.“Evolutionary biology and the theory of evolution is in the standards,” Mack said. But several parents and teachers who attended an evening forum on the state’s proposed science standards criticized the proposal by the Florida Department of Education, which Mack runs, specifically the handling of evolutionary science.Joshua Garrett, a teacher in Orange County Public Schools, said the state’s proposed standards “danced around” evolution.State standards are benchmarks for what students should learn in their classes kindergarten through 12th grade, guiding what lessons are taught, what subjects are in state-approved textbooks and what concepts are tested on state exams.Florida’s current science standards call evolution a “big idea” and “the fundamental concept underlying all of biology.”The proposed ones barely mention evolution — a scientific theory explaining change in living species over time from natural selection that has been a cornerstone of biology for more than a century. The term “evolution,” in fact, is never defined in the new high school life sciences standards, though the concepts are sprinkled across several units.The education department has made revisions to its proposal, officials said, but it was not immediately clear at the Tuesday forum, held at Lake Buena Vista High School in southwest Orange County, what those changes were.Mack interjected during Garrett’s comments asking him where specifically he wanted the state to mention evolution more prominently. Then he said, “Consider it done.”Mack also asked Garrett to join the state’s faculty committee on the standards.The state released the new standards in September, and several experts quickly criticized them, saying they lacked depth and skirted around both evolution and climate change, important topics for Florida students to learn.The state has since hosted a “listening tour,” including a virtual forum and two other in-person meetings in Walton and Hillsborough counties. Tuesday’s meeting drew a small crowd of about 30 people, six of whom spoke.Mack described the state’s public forums as a chance for “myth busting” and to make clear Florida’s position.He wants to students to learn “above ideology,” he said, and added that evolution isn’t settled science. TNCMS.AdManager.render({region: 'fixed-big-ad-middle-asset', slot: 1, fold: "span"}); “I want to cultivate skeptics in the healthy sense of that term. As a result of these standards, students should not be walking away convinced of anything other than the rigor of the scientific method,” Mack said.The new standards would replace the current set, adopted after a monthslong, statewide fight over the inclusion of evolution as a required subject of study. Those who opposed the 2008 standards argued creationism, or the biblical story that God created all living things, should be taught alongside evolution.Thomas Simon, a Winter Park parent, compared Florida adopting the new standards to Nazi Germany ignoring the findings of Jewish scientists — which in part lost them World War II.“If this board could explicitly name communism in the history standards last year — because words matter — you must explicitly name the foundations of modern medicine, agriculture, and energy,” Simon said.Florida last year adopted new standards that require students learn about the “dangers and evil of communism.”Teri O’Connor, an elementary science teacher in Orange County, urged Mack to curtail the total number of standards, as they list more than 1,000 benchmarks teachers are to cover during their classes.“It’s only 180 days of school. That right there is an issue, especially if you want to dive in. If we need to teach the rigor of it and to critically think about each one, that’s difficult,” she said.Kathleen Murray, who spoke on behalf of the conservative political group Citizens Defending Freedom, said she was in “strong support” of the proposed standards. Science should teach children how to think, not what to think, she said.“When teaching the origins of life and the universe, the curriculum owes it to the Florida students to be honest about the limits of what scientific models can actually prove,” Murray said.State education officials said they’d received about 1,800 comments on the benchmarks, and they have updated them based on that criticism.With Tuesday the state’s final scheduled public forum, Mack said his biggest takeaway was that the standards needed to be more explicit about teaching students how to evaluate scientific studies and evidence and how to understand the scientific method.“We might have to do a better job of helping students question more as a result of these standards,” he said.In his original statement when the standards were announced in September, Mack wrote in a social media post that “science begins in wonder, not in ideology,” and “the classical tradition taught that nature is intelligible because it is ordered — that the book of creation can be read by reason.”Some read that to mean he was trying to interject religion into public school education. 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Purple Line Small Business Grants: Apply by November 7
The Maryland Department of Transportation is accepting applications for the third round of 2026 Purple Line Small Business Grant Program awards.
Mexico City GP: Lando Norris pips Kimi Antonelli in final practice to set up thrilling Mexico qualifying
Lando Norris and Kimi Antonelli were separated by just 0.001s at the top of the timesheet in final practice for the Mexico City Grand Prix; watch qualifying later at 9pm with Sundays race at 8pm (build-up from 6.30pm), live on Sky Sports F1
Charles County Health Officials Report Early Flu Season, Urge Shots Before Holidays
LA PLATA, Md. — With flu cases already showing up in Charles County and holiday gatherings approaching, health officials are encouraging residents to get vaccinated before the season picks up. Residents can get a flu shot during weekday walk-in hours at the Charles County Department of Health, with another opportunity coming Saturday, Nov. 7, at […]
Downtown Orlando businesses prepare for Halloween crowds with extra security
Ensuring that customers and employees feel safe among Halloween crowds is a priority as the area marks two years since a deadly shooting.
U.S. Department of Education demands changes to Illinois school mental health screening plan
The Department of Education raisse parental consent and privacy concerns over mental health screening plans.
US health department to remove broad black box warning from three estrogen patch products
Oct 30 () - The US health department on Friday approved the removal of the strictest "black box" warnings from the labels of three estradiol transdermal patches, the hormone therapies used to treat ...
2027 ProRodeo Playoff Series Destinations Announced
Three new rodeos join the schedule as the PRCA prepares for another season of high-stakes competition in 2027.
Kyle Whittingham looks ahead to Michigan State after Rutgers win
Michigan coach Kyle Whittingham prepares for his first rivalry game against Michigan State after beating Rutgers.
Louisiana health officials warn against amoeba infections from tap water
Louisiana health officials are warning the public not to use tap water for nasal rinses or contact lenses after two serious amoebic infections have been reported this year. Although the patients reported using tap water for sinus irrigation, the state health department said it has not established tap water as the source of their infections
Club Confirms Scottish Midfielder’s Departure on Loan
Connor Barron trades Rangers for Middlesbrough in a season-long move, but a lack of playing time and conflicting buyout reports spark rumours of a potential January recall.
Justice Dept. Confirms Alaska Inquiry Even as Its Focus Remains Unclear
Democrats and former officials have accused the department of pursuing a political goal in the guise of a legal one: to publicize a scheme, sordid but not illegal under state law, damaging to Democrats.
South Texas Health System (@stxhealthsystem)
1 likes, 0 comments - stxhealthsystem on November 1, 2026: "Develop Your Career at the Speed of Imaging: South Texas Health System is seeking talented radiology professionals to join our award-winning imaging teams across the Rio Grande Valley, including our four acute care hospitals and seven freestanding emergency departments. Take your career to the next level with the region's largest integrated healthcare network, where you'll have the opportunity to make a meaningful impact on patient care every day. STHS offers competitive pay, comprehensive benefits and sign-on bonuses for qualified candidates. Ready to bring your career into focus? Explore current opportunities and apply today by clicking on the link in our bio. #NowHiring #Radiology #STHS #RGV #EmploymentOpportunity".
Attorneys for Alaska say 'meritless' Trump demand to set aside Senate ballots 'not even possible'
The Department of Justice on Friday added a request that the judge separate all ballots showing votes for the second Dan Sullivan until it can be determined whether voters were fooled into wasting their votes for a spoiler candidate.
Wanted: New Central Bank Chief. Expertise and Political Acumen Required.
The looming departure of the European Central Bank’s president, Christine Lagarde, has set in motion a high-stakes search for her successor.
Ward and Smith: Tariff Refunds
••• SPONSORED SECTION ••• TARIFF REFUNDS: What Your Business Could Still Recover by Kelly Reid In February 2026, the Supreme Court ruled that the International Emergency Economic Powers Act (IEEPA) did not authorize the President to impose tariffs. That decision opened the door to refunds of IEEPA duties, including the broad “reciprocal” tariffs introduced in […]
Jack Nicholson's Only Sci-Fi Movie Was An Underappreciated '90s Classic
When one reminisces about Jack Nicholson's filmography, they likely remember his biggest hits like The Shining, Batman from 1989, The Departed, or Chinatown.
Arsenal trio could be back for the match against Liverpool
Arsenal are preparing for a crucial Premier League clash against Liverpool this weekend, with the fixture set to provide one of their toughest tests of the campaign.The Gunners remain among the favour...
Rising health costs and coverage changes are big concerns for older adults as Election Day nears
WASHINGTON — Barbara Weigand could not have prepared more for retirement. She stayed healthy and saved diligently for years. This year, though, a shoulder surgery and a bladder cancer diagnosis have really tested her finances. She recently withdrew $4,000 from her retirement account to cover medical expenses associated with her
Louisiana health officials warn about rare amoeba infections after certain tap water use
The Louisiana Department of Health is warning residents about the risks of using tap water to rinse nasal passages and clean contact lenses after rare amoeba infections.
Judge orders Trump administration to stop threatening election officials with criminal charges
The Justice Department recently sent letters to state and local election officials across the country warning them of criminal penalties related to failing to comply with records retention.
Buitoni to close Danville plant, lay off 251 employees
Buitoni plans to close its Danville pasta plant Dec. 28, eliminating 251 jobs as the company prepares to shut down operations.Buitoni plans to close its Danville pasta plant Dec. 28, eliminating 251 jobs as the company prepares to shut down operations.
The surprising science-backed ingredient in this $198 anti-aging serum
DefenAge 8-in-1 BioSerum costs $198 and uses Age-Repair Defensins®. Here's the science behind the anti-aging serum and what research shows.
Bayer wins Roundup weedkiller cancer trial while awaiting settlement ruling
Bayer won a trial on Thursday over claims by three women that its Roundup weedkiller caused their cancer, while awaiting a broader ruling from a separate court on the company’s $7.25…
North Carolina A&T issues statement on Elon homecoming brawl
North Carolina A&T Athletics has released a statement regarding the brawl f ollowing the team’s homecoming victory over Elon. Members of the two football teams got into a physical altercation immediately following the game on North Carolina A&T’s sideline. The full statement from North Carolina A&T’s Department of Athletics is below. “An on-field […] The post North Carolina A&T issues statement on Elon homecoming brawl appeared first on ClutchPoints.
Paris FC predicted XI v Monaco: Luca Koleosho out
Paris FC will be without winger Luca Koleosho as they prepare to host AS Monaco at the Stade Jean Bouin on Sunday afternoon. Koleosho, an Italy international who has been in fine form in recent weeks,...
#3 USC Women ready prepares for highly anticipated season
On Monday in Las Vegas, the USC Women’s basketball team could be entering its greatest season in history.
DEA Refuses To Approve Marijuana Businesses In States That Allow Dual Medical And Recreational Licensing
While the Department of Justice announced on Friday that it has given federal registration and protections to more than 900 medical cannabis businesses across the U.S., it is also refusing to extend such approvals to cannabis operators in certain states. According to an order DEA officials sent to a marijuana business in Minnesota, the agency […]
Science Begins With Wonder and Sometimes With a Salamander.
The Bar Harbor Story is generously sponsored by the Don & Beth Straus Center at Birch Bay Village. BAR HARBOR—The children had come to see the axolotls, those odd little salamanders with pink frills around their heads and the remarkable ability to grow back what they lose. But also there were stickers. There were crafts. There was the kind of excitement that makes a roomful of kindergarteners forget, for a little while, that sitting still is ever a requirement. And then there were the animals themselves, alive in their clear cases at the MDI Biological Laboratory, where 12 children from Pemetic Elementary School got to meet the creatures they had been learning about in class. “Do you love them?” their teacher, Carol Null, asked. The answer came back in a chorus. “I do!” “I do!” “I do too,” Null said, smiling. “I love them even more now.” That was the thing about a day at the lab. Science was no longer a picture in a book, or a word on a classroom wall. It had a face, a tail, and a set of extraordinary powers. And for a child, sometimes that is where wonder begins. Sometimes learning about science is about stickers. Sometimes it’s about bright pink feathers and getting super excited about that glow in the dark. Sometimes learning about science is joy—pure and simple joy. That’s how it was October 28 at the MDI Bio Lab as Miss Hannah (known in the lab as Dr. Hannah Lust, director of STEM, undergraduate and graduate Training), other scientists, graduate students, and MDI Bio Lab staff, hosted 12 students from Carol Null’s Pemetic Elementary School’s kindergarten class. The 2.5-hour program created by Dr. Lust focused on axolotls, a species of mole salamanders, a superhero in the animal world: a superhero with some scientific-study worthy superpowers. One of those superpowers come from the axolotls’ ability to regenerate body parts, including entire limbs. But also, they’re cute. This fall, before coming to the internationally renowned lab nestled in Salsbury Cove, Null has been integrating axolotls into her class. They’ve been part of the kids’ vocabulary and their storytelling. They’ve been part of science. They’ve been part of the children’s learning about facts vs opinions. The Pemetic Elementary kindergarten students learn about invasive species and the impact on the ecology and one student related it to their dad, who lobsters, and his worries about green craps, an invasive species in Maine. “Are they bigger or smaller than you thought they’d be?” the children are asked after the scientists show them multiple see-through cases of axolotls, lined up on a table that they’re told not to jiggle. “Bigger!” “I think they’re bigger.” “Smaller!” The bio lab opening its doors to the collaborations and to students and families is a norm, but this is the first program of this kind. It’s meant to encourage kindergarten students about axolotls. But when the students come to the bio lab something else happens too—something beyond Null’s child-focused teaching—the students see science—and the regenerating creatures in real life. They do crafts. They speak with them. They meet people who know all about them: scientists and educators who talk to the kids like they’re equals. That’s a superhero power, too. Null speaks about meeting the kids where they’re at in her classroom, letting their interest and hearts lead her in their learning. That requires recognition of interests, of individuality, of empathy. Some would argue that’s a super power, too, but it’s also in those 12 students as they listen to the storybook, encounter those live axolotls, and hear about how axolotls might help advance society’s understanding of human health. As Eddie Seckeler (comparative animal models, CORE facility manager), carefully puts the axolotls on a cart and rolls them away, some of the children stop what they’re doing to watch. “Bye axolotls.” “Bye!” “Bye!” The axolotls are not just images in a book, Hello, I’m an axolotl by Hayley and John Rocco; they are real and cool. MDI Biological Laboratory scientists Dr. Prayag Murawala and Dr. James Godwin who both feature in the Roccos’ book. The kindergarteners get to meet them in real life, off the page, in the world, doing science. They learn from them, laugh with them. “The visit is about more than meeting an unusual animal. By introducing children to scientists working in their own community, the experience helps make science tangible and accessible. Students can see that science is not just something they read about in books or learn about at school. It is something real people do every day by asking questions, making observations and working to understand how the world works,” explains MDI Biological Laboratory Director of Communications Rebecca Woods. While the students make axolotl-related crafts around tables, graduate students and staff help out. Ryan holds up his construction paper setting and axolotl to show Omar Maged, a graduate student. “Do you like it?” Ryan asks, eyes wide, turning from his axolotl to look up at Omar. Omar studies the construction paper for a moment, smiles and says definitively, each word important. “It is beautiful.” Null says that she’s so thankful for all the “amazing” community partners that her school and her students get to interact with as they learn and grow and live, but emphasized how the MDI Bio Lab goes out of its way to create something meaningful, something that allows her young students to build their own agency, to know that they can be impactful in their community, to show them how how things they learn about in text is connected to themselves and their community. Woods explains, “Axolotls have an extraordinary ability to regenerate, or regrow, certain body parts, including limbs. Scientists study these animals to understand how regeneration works and what their biology might teach us about tissue repair and healing in humans.” The children enter the space for “a memorable introduction to a big scientific question,” Woods said. “How can some animals regrow body parts? The encounter encourages children to look closely, wonder about what they see and begin to understand how scientists use observations and experiments to investigate questions.” “For the students, the visit is an opportunity to explore a fascinating animal and meet scientists in their own community,” Woods explains. “For MDI Biological Laboratory, it is a chance to share the excitement of research, nurture curiosity, and help young learners discover that science begins with asking questions.“ At the beginning of the school year, Pemetic kindergarteners didn’t know what the axolotl was—at least not exactly—now they know all about the axolotl’s life cycle. “It’s different than a butterfly,” one student told Mrs. Null. It is. The change and knowledge might seem small**,** but it offers a glimpse of what happens when a subject moves beyond the pages of a book and into a child’s world. The children have been learning about butterflies at the Charlotte Rhoades Park and Butterfly Garden. At both the garden and the MDI Bio Lab, the children see the animals, meet the scientists who study them and at the lab encounter a question that researchers are still working to answer: how can some creatures regenerate body parts, and what might that teach us about healing in humans? They leave with gift bags, paper-plate salamanders, new things to wonder about and a connection between the science they learn in school and the work happening in their own community. The axolotls may be remarkable for their ability to grow back what they have lost. For these young students, the day offers something different: a chance to discover how much there is to ask, observe, and imagine. When Null’s students had time to use chalk and draw whatever they want, in the beginning of the year, they drew rainbows. Now? They’re using that chalk and choosing to draw axolotls instead. About MDI Bio Laboratory For more than 125 years, MDI Bio Lab has been a center for training and research in comparative biology. In the last two decades its biomedical research has focused on aging, regeneration, and environmental toxins. The Laboratory houses 11 research groups staffed by an international team of world-class scientists and graduate students. It also leads a statewide network of colleges, universities and research institutions that collaborate to provide training, research experiences and financial support to help young Mainers play a bigger role in today’s biomedical revolution. Located on Maine’s rugged coast, the Laboratory’s 100+ acre campus houses research facilities, cottages and dorms that house visiting scientists and students. It is also home to MDI Bioscience, a subsidiary working to design innovative techniques to speed the drug discovery process. The Bar Harbor Story is generously sponsored by Rick Osann Art. LINKS TO LEARN MORE NIH INBRE MDI BIOLOGICAL LABORATORY Pemetic Elementary School Hello, I’m an Axolotl Photos: Carrie Jones/Bar Harbor Story HELP SUPPORT THE BAR HARBOR STORY When we started The Bar Harbor Story, we didn’t know if anyone would read it. But you showed up. You shared. You sent tips. Now—over 400,000 views every month later—it’s clear: people here care about their community and each other. We’ve kept everything free because news should never be out of reach, but every one of our stories takes time to write, and your support keeps The Bar Harbor Story going. If you value our work, please consider a paid subscription, a founding membership, or a sponsorship. It truly helps us cover one more meeting, tell one more story, shine one more light. Even $5 a month makes a difference. Click here to become a one-time supporter now. Thank you so much for being here. Founding member information can be found here. Have questions about sponsorships? Just send Shaun an email at sfarrar86@gmail.com, he’d love to hear from you. Subscribe Share Bar Harbor Story Share Leave a comment
Nicholls Athletics expands partnership with Thibodaux Regional Health System
Nicholls State University’s athletics department announced the expansion of a partnership with Thibodaux Regional Health System in a press conference on Friday. The expansion allows Nicholls athletes—including members of the soccer, tennis, beach volleyball and track programs—access to Thibodaux Regional’s new, National Collegiate Athletic Association-compliant sports complex. The complex allows Nicholls to host competitive and...
Laramie County health and food inspections (10/23/26–10/29/26)
CHEYENNE, Wyo. — The Cheyenne-Laramie County Health Department inspects restaurants, bars, convenience stores, delis, grocery stores, bed and breakfasts
Analysis: More than 40% of names on DOJ list of alleged noncitizens not on California's voter rolls
It's the first outside analysis of a list that the Department of Justice has used to threaten prosecution of election officials. The analysis also found that thousands of U.S. citizens appear to be flagged as ineligible to vote on the government's list.
Wisconsin Department of Health Services warns of phishing scam
The Wisconsin Department of Health Services is warning its partners about a new phishing scam.
Charles County Health Department Faces Potential Cuts As Demand For Services Grows
LA PLATA, Md. — Charles County’s health department is preparing for a potential 12% cut to the Local Behavioral Health Authority while working to expand access to care for residents. The state requested a plan for the possible reduction, commissioners learned during a biannual health department briefing Tuesday, Oct. 27. According to the Charles County […]
Valve's Cancelled Portal Prequel F-Stop Has Leaked
Three separate Valve leaks have been combined a fully playable version of the cancelled 2007 game F-Stop
35-year-old took on $20K in debt to launch a business from her dining room—now it brings in 8 figures a year
Set Active founder Lindsey Carter shares how she learned to separate her professional stress from her personal life while growing her athleisure company.
Velocity/Impel | Virtual tour generated by Panotour
Take a 360 degree virtual tour of Pierce's customizable Velocity® & Impel fire truck chassis. Built specifically for each department's needs, these affordable yet fully-featured chassis deliver ideal configurations via standard and optional features.
Health dept issues violation for broken elevator at Indy apartment complex
INDIANAPOLIS– The Marion County Health Department has issued a violation notice to an Indianapolis landlord after residents complained their only elevator has been broken for several weeks. Tenants at the Commodore Apartments, located at 30th and N Pennsylvania St, are having a hard time getting groceries up and down the stairs. Anthony Foreman is in […]
Wendy Brown, political scientist: ‘Our organization of life is unsustainable and we know it’
The California philosopher, one of the leading figures in her field, argues for a reparative democracy centered on collective care to help repair the damage caused by neoliberalism
Halloween meets game day: How Sixth Street is preparing for a packed night
With Halloween and a University of Texas game bringing crowds downtown tonight, APD expects 80,000 to 100,000 people in the entertainment districts...
The Harvard Crimson (@theharvardcrimson)
49 likes, 0 comments - theharvardcrimson on October 30, 2026: "From @fmcrimson: At 7 p.m. on April 11, 2014, a panel of six sat onstage behind a long table at the University of Massachusetts Amherst, preparing to speak. They arranged their notes on the wrinkled plastic tablecloth. The panelists weren’t there to discuss their academic work. Rather, they were speaking about their time as members of the Vietnam-era movement Science for the People, a radical organization who believed science had been misused by capitalist interests. Allen S. Weinrub, who co-founded Science for the People in 1969, sat on the far end of the table. He wore a button with the organization’s emblem: a red fist beside a hand grasping an Erlenmeyer flask. The organization was part of the anti-war movement in the 1960s. Early members of Science for the People were protesting the use of sciences like chemistry and physics to develop weapons — but increasingly critiqued science as a reflection of power imbalances in capitalist society. Full story linked in bio. 🖋️: Sophie Gao 📷: Dawn Chen, Courtesy of Science for the People Archive and Courtesy of MIT Archives".
Miami Dade College-School of Health Sciences: Bachelor of Science in Dental Hygiene Program to Meet Workforce Needs - Florida Hospital News and Healthcare Report
Dr. Ron Winston, Dean of the School of Health Sciences Miami Dade College (MDC), through its renowned School of Health Sciences, has launched a new Florida Department of Education-approved Bachelor […]
Appeals court rejects Justice Department request for California to set aside disputed ballots
The 2-1 ruling by the 9th Circuit Court of Appeals panel is the latest setback for the Trump administration’s efforts to assert control over state-run elections.
I'm a Tax Attorney: 5 Moves Small Business Owners Should Make Before Election Day
Small business owners can prepare for filing season and possible policy changes by reviewing books, taxes, payroll and compliance now.
Jeff Ekhator hands Luciano Spalletti a huge fitness boost
Jeff Ekhator has returned to full training, providing Luciano Spalletti with a timely fitness boost as Juventus prepare for a crucial match against Napoli. The striker’s recovery comes at an importa...
Rising health costs and coverage changes are big concerns for older adults as Election Day nears
WASHINGTON (AP) — Barbara Weigand could not have prepared more for retirement. She stayed healthy and saved diligently for years.
Tips for Michiganders on purchasing health insurance when open enrollment begins Nov. 1
The Michigan Department of Insurance and Financial Services is encouraging ACA marketplace enrollees to get ready before the start of open enrollment.
Space Shuttle Endeavour's new LA home unveiled ahead of public opening
The California Science Center is preparing to open the Samuel Oschin Air and Space Center, a 200,000-square-foot expansion that will showcase Space Shuttle Endeavour.
Community Halloween Safety Reminders
As neighborhoods prepare to celebrate Halloween, the Central MA Regional Health Department would like to remind residents and motorists to take simple precautions to ensure a fun, healthy, and injury-
Rising Health Costs and Coverage Changes Are Big Concerns for Older Adults as Election Day Nears
WASHINGTON (AP) — Barbara Weigand could not have prepared more for retirement. She stayed healthy and saved diligently for years. This year, though, a shoulder surgery and a bladder cancer diagnosis have really tested her finances. She recently withdrew $4,000 from her retirement account to cover ...
2026-2027 Audree V. Fowler Fellows in Protein Science
Graduate students Lenka Milojević (Zhou group), Akshaya Narayanasamy (Lindert group), Sarah Singleton (Conway group), and Janet Zhong (Feigon group) have been selected as 2026–27 Fowler Fellows and shared their research at a special event on Oct. 13, 2026. 2026-27 Fowler Fellows – Sarah Singleton, Lenka Milojević, Janet Zhong, and Akshaya Narayanasamy. Akshaya Narayanasamy and Prof. Steffen Lindert. Sarah Singleton and Prof. Stuart Conway. Janet Zhong and Prof. Juli Feigon. About the 2026-27 Audree Fowler Fellows in Protein Science Lenka Milojević is a fifth-year Biophysics Ph.D. candidate in the lab of Professor Z. Hong Zhou at UCLA. As an undergraduate at Maastricht University, she studied the structural basis of Mycobacterium tuberculosis virulence and amyloid-β fibril nucleation in the lab of Professor Peter Peters. She completed her bachelor’s thesis research at UCLA in the lab of Professor David Eisenberg, focusing on amyloid disaggregation, before beginning her doctoral studies. In the Zhou lab, Lenka uses cryo-electron tomography to visualize and characterize membrane-associated protein assemblies across a range of viral and cellular systems. Akshaya Narayanasamy is a fifth-year Ph.D. student in the Department of Chemistry and Biochemistry at UCLA, mentored by Professor Steffen Lindert. She earned her B.S.-M.S. in Chemistry from the Indian Institute of Science Education and Research, Thiruvananthapuram, where she worked in Professor Mahesh Hariharan’s lab investigating how single-atom substitutions influence crystal packing and charge transport behavior. She received her M.S. in Physical Chemistry from The Ohio State University before moving with the Lindert lab to UCLA. At UCLA, Akshaya develops integrative modeling methods that combine deep learning and Rosetta with experimental data, such as ion mobility mass spectrometry and cryo-EM, to improve protein structure prediction. Her current work focuses on developing an experimentally guided diffusion model and designing de novo protein binders with potential antibacterial activity. Ultimately, she aims to bridge AI-based structure prediction and experimental data to make computational protein models more reliable for drug discovery and therapeutic design. Sarah Singleton is a 4th year BMSB student, working in Professor Stuart Conway’s lab. She earned her B.S. in Biochemistry at Simmon University (Fenway, MA). Her research is centered on drugging the previously undruggable class of proteins—transcription factors. Zinc finger (ZF)-containing transcription factor proteins typically contain multiple ZF motifs, but little is known about the principles that govern the recognition of multi-ZF arrays by immunomodulatory imide drugs (IMiDs). In a multi-ZF array that contains several potentially targetable ZFs, which will be accessible and why? How does the surrounding protein architecture inform IMiD recognition? Sarah’s research aims to utilize her findings on the fundamental principles of ZF recognition to design IMiD therapeutics for transcription factors involved in health and disease. Janet Zhong is a fourth-year BMSB student, working in Professor Juli Feigon’s laboratory. She received her BSc and MRes from Imperial College London. At UCLA, Janet combines cryo-electron microscopy (cryo-EM) and biochemical approaches to investigate how proteins and RNAs assemble into ribonucleoprotein structures. Her research focuses on telomerase, the enzyme that maintains chromosome ends, with interests in its structure, assembly, and mechanisms. She has also worked on capturing the cryo-EM structure of a small bacterial non-coding RNA called raiA motif RNA. About Dr. Audree Fowler A strong supporter of the basic sciences and medicine at UCLA, alumna Dr. Audree Fowler (B.S. ’56 chemistry, Ph.D. ’63 biochemistry) established the Audree V. Fowler Fellows in Protein Science in 2008. Fowler was Director UCLA Protein Microsequencing Facility from 1984-1999 and is a Researcher Emeritus of the UCLA Department of Biological Chemistry. She is one of the first four women to receive a Ph.D. from the UCLA Department of Chemistry & Biochemistry. In 2018, the women were awarded the department’s 2018 Alumni Legacy Awards in recognition of their achievements in life, and generous support and service to UCLA. “The sciences gave me a great life. Now I want to help others have access to the same opportunities I enjoyed,” Fowler explained when she established the Fowler Fellowships endowment. Applications for the fellowships are solicited from graduate students in the Molecular Biology Interdepartmental (MBI) Ph.D. Program, Biological Chemistry, and Chemistry & Biochemistry Departments. In addition to presenting their research at a special seminar, the recipients each receive a $5,000 award. Previous Fowler Fellows from the UCLA Department of Chemistry & Biochemistry 2025-26 – Nikki Cheung (Clubb Group), Jonathan Jih (Zhou Group), Eileen Olivares (Loo Group), and Lily Taylor (Rodriguez Group) 2024-25 – Andrew Goring (Clubb lab), Eric Pang (S. Clarke and Rodriguez labs), and Miranda Villanueva (Backus lab) 2023-24 – Alexandra Turmon (Backus lab), Cindy Wang (S. Clarke and C. Clarke labs) 2022-23 – Cody Gillman (Gonen lab), Declan Evans (Houk lab), Troy Lowe (S. Clarke lab), Ashley Julio (Backus lab), and Alex Stevens (Hong Zhou lab) 2021-22 – Weixian Deng (Wohlschlegel/Plath labs), Yi Xiao “Sean” Jiang (Eisenberg lab), Maria Flores (Rodriguez lab), Carter Lantz (Loo lab), and Logan Richards (Rodriguez lab). 2020-21 – Janine Fu (Loo lab), Calina Glynn (Rodriguez lab), and Jiahui Lu (Eisenberg lab) 2019-20 – David Boyer (Eisenberg lab), Orlando Martinez (Clubb lab) and John Muroski (Loo lab) 2018-19 – Scott McConnell (Clubb lab), Kevin Murray (Eisenberg lab), Rebeccah Warmack (S. Clarke lab) 2017-18 – Michael Hughes (Eisenberg lab), Yuxi Liu (Yeates lab), Kanishk Jain (S. Clarke lab) 2016-17 – Brendan Amer (Clubb Lab) and Jeff Vinokur (Bowie Lab) 2015-16 – Henry Chan (Feigon lab), Smriti Sangwan (Eisenberg lab), Nicholas Woodall (Bowie lab) 2014-15 – Dan McNamara (Yeates lab) 2013-14 – Alex Jacobitz (Clubb lab), Alexander Patananan (S. Clarke lab), Carly Ferguson (Loo lab) 2012-13 – Letian Xie (C. Clarke lab), Anni Zhao (Eisenberg lab) 2011-12 – Timothy Anderson (Clubb lab), Soohong Kim (Weiss lab) 2010-11 – Zeynep Durer (Reiser lab), Cecilia Zurita-Lopez (S. Clarke lab) 2009-10 – Luki Goldschmidt (Eisenberg lab), Kristofer Webb (S. Clarke lab), Sheng Yin (Loo lab) 2008-09 – Nathan Joh (Bowie lab), Neil King (Yeates lab) Photos courtesy of Helen Houldsworth, the Molecular Biology Institute.
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Business Owners Have a Window. Most Aren't Ready to Use It. by Tully Ryan
I spend my working life on both sides of a business sale. As an M&A advisor based in Wilmington, I help lower middle market owners across North Carolina, South Carolina and Virginia sell what they've built. As the founder and CEO of IQExit, I work with the bankers, wealth advisors, CPAs and attorneys who sit beside those owners for years before a sale ever comes up. From both seats, I keep seeing the same thing. The market is ready for our owners. Too many of our owners aren't ready for the market. Start with our own backyard. Wilmington's metro area added more than 12,000 residents between July 2024 and July 2025, a 2.6% jump that ranked seventh in the country. It also posted the highest job growth rate of any metro in North Carolina. I see the same pattern in the growth markets I work in across the Southeast. New residents mean new customers and new workers. They also mean new buyers: people who moved here from corporate jobs and want to own something, private equity groups looking for add-ons in HVAC, electrical, landscaping and other trade services, and younger entrepreneurs who would rather buy a running business than start one from scratch. The ownership numbers are hard to ignore. About half of North Carolina's small businesses have an owner who is 55 or older, and roughly 85% of those owners have no succession plan, according to the North Carolina Employee Ownership Center. Nationally, more than half of Baby Boomer business owners have no documented transition plan. That isn't a crisis yet. It's a timing problem. A lot of businesses will change hands over the next decade, and the prepared ones will get the better buyers and the better terms. Buyers have money and they're using it. But an active market doesn't mean a fast one. The IBBA's latest Market Pulse survey found that Main Street deals took six to 10 months from engagement to close in the second quarter, and lower middle market deals took 11 to 12 months. That clock starts after the owner decides to sell. In my experience, the real preparation has to start years before. Two clocks, two playbooks When I sit down with an owner or their advisor, my first question isn't “What's it worth?” It's “When?” The answer puts the owner in one of two groups. If the owner wants out within 24 months, we're in execution mode. There's no time to rebuild the business. The work is cleaning up what a buyer will test: three years of financials that tie to the tax returns, an add-back schedule you can prove, customer and vendor contracts in writing, a lease that can be assigned, and a price the market will actually pay. The goal is certainty to close. If the exit is two to five years away, the owner has something worth more than time. They have choices. That window is where most value gets built, and most owners waste it by waiting. What kills deals In the lower middle market, deals rarely die over the headline price. They die in diligence, or they get retraded late in the process. I see the same causes again and again. The owner is the business. If every key customer relationship runs through the owner's cell phone, a buyer sees risk and a lender sees more of it. The books don't hold up. Buyers spot weak accounting fast. Statements that get revised mid-process, a revolving door in the bookkeeper's chair, revenue tracked on a side spreadsheet, and margins that slip while sales climb with no clear reason all make a buyer nervous. So does an owner who pushes back when asked for documents. And plenty of private owners run personal expenses through the company. Add-backs are normal. Add-backs you can't document turn into a lower offer. The real estate isn't sorted out. Many owners hold their building in a separate LLC. That's fine, but the lease terms or the property sale should be settled before a buyer shows up, not halfway through diligence. Revenue sits in too few hands. Picture a contractor with 40% of its work coming from one builder, or a service company running on handshake deals. Buyers will still look, but the terms shift toward more seller financing, an earnout, or less cash at closing. Owners and advisors: if your exit is three to five years out • Get a baseline now. Find out where the business really stands today: what a buyer would pay, who that buyer is likely to be, and which gaps would hurt you in diligence. You can't fix what you haven't measured, and the answer is often different from what the owner expects. • Make yourself less necessary. Spend the next few years building a manager or small team that can run daily operations and own customer relationships. Put handshake deals into written contracts. A business that runs without its owner is worth more and is far easier to finance. • Clean the books for three straight years. Buyers and lenders look back at least three years. Separate personal expenses, keep the financials tied to the tax returns, track every add-back as you go, and settle the real estate plan early. A word to CPAs CPAs often see a sale coming before anyone else, and you're usually the most trusted voice an owner has. Year-end meetings are the right time to start this conversation. Here's what I'd ask every CPA to do this season with business owner clients over 55: • Ask the timing question. “Do you see yourself owning this business in five years? If not, who takes it over?” Write down the answer and bring it up again at next year's meeting. • Run a proof of cash and review revenue recognition. Make sure the cash in the bank ties to the revenue on the books. Pay close attention to contractors with work in progress and to companies selling memberships or service plans. These issues are easy to fix with years of lead time and painful to fix a month before closing. • Pair the tax return with an exit readiness review. Invite clients to complete IQExit's Exit Readiness Intelligence (ERI) process as part of year-end planning. It gives you and the client a shared picture of readiness gaps and an indicative value range, and the results come back to you as the advisor. That turns a tax meeting into a planning relationship, and it puts you in position to bring in tax and M&A help early, when choices like purchase price allocation can still save the client real money. Changing the conversation For bankers, wealth advisors and attorneys, the hard part is raising the subject without seeming to nudge a client toward the door. I understand that. Nobody wants to tell a 60-year-old owner it's time to sell. So don't. Ask a different question: “If a buyer called tomorrow, what would they find?” That's a planning question, not a pitch, and it's useful whether the exit is two years out or 15. It's the question we built IQExit to help advisors answer. Whether you're in Wilmington, Raleigh, Charleston, Richmond or anywhere else, owners have a real opening right now. The buyers are out there and so is the capital. The owners who come out ahead will be the ones who start getting ready before they're ready to sell.
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