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Yan Leyfman: Real-World Outcomes After First-Line Osimertinib in EGFR-Mutant NSCLC
Yan Leyfman: Real-World Outcomes After First-Line Osimertinib in EGFR-Mutant NSCLC / cancer, EGFR-mutant lung cancer, FLAURA2 Trial, Lung cancer, NSCLC,
2nd PET scan changes treatment for nearly half of prostate cancer patients
Managing recurrent prostate cancer after first-line treatment remains a key clinical challenge, experts write in The Journal of Nuclear Medicine.
Uniting to respond to mental health impacts of digital violence
Technology-facilitated gender-based violence (TFGBV), from doxxing and cyberstalking to cyberbullying and online harassment, is reshaping how women and girls navigate digital spaces. Globally, an estimated 23% of women have experienced digital violence. In Indonesia, reported cases of TFGBV reached 1,791 in 2024, a 40.8% increase from the previous year. Yet very few survivors seek help, leaving lasting effects on their mental health and wellbeing. As part of the multi-UN agencies UNiTE campaign for the 16 Days of Activism against Gender-Based Violence, the World Health Organization (WHO) and the Ministry of Health (MoH) co-hosted a talk show on 6 December 2025 to spotlight this urgent issue. The event brought together voices from Meta, the Indonesian Clinical Psychologist Association and Dr Vivi Syarif, a WHO Fides content creator, creating a cross-sectoral dialogue on the magnitude and mental health impact of digital violence. The talk show introduced psychological first aid as a vital initial intervention that communities can provide to survivors. This intervention aligns with the Psychological First Aid: Guide for Field Workers, a framework that has been standardized for over a decade. The "look, listen, link" approach focuses on ensuring safety and urgent needs, reassuring survivors and connecting them to appropriate services. In addition to this public health approach, Meta also outlined mechanisms to respond to digital violence and reaffirmed its commitment to building safer digital spaces by continuously updating community guidelines based on user feedback. Such collaborative discussions help connect community engagement initiatives with daily digital life. They empower audiences not only to understand how the health sector and industry are responding, but also to educate others, promote first-line support and encourage referrals to appropriate help. By fostering awareness and engagement, these dialogues strengthen collective resilience against digital violence. Written by Jessie O. Yunus, National Professional Officer (Gender, Equity, Rights and Disability Inclusion), WHO Indonesia
ASU-led project to examine psychedelic therapy for mental health
About 30% of people diagnosed with depression don’t respond to standard first-line medication or therapy. With post-traumatic stress disorder, the nonresponse rates to medication and cognitive behavioral therapy may be as high as 40% and 50%, respectively.
Policymakers And Lawmakers Eyeing The Use Of AI As A Requisite First-Line For Mental Health Gatekeeping And Therapy Intervention
Should we use AI to pre-screen whether people can see a human therapist? And should we use AI to do initial intervention? It's a huge controversy. An AI Insider scoop.
Lilly's Jaypirca approved as first-line CLL therapy
Eli Lilly’s Jaypirca has won FDA approval for previously untreated chronic lymphocytic leukemia and small lymphocytic lymphoma.