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Analysis | Five races that will tell us where election night is headed
A handful of House, Senate and governor’s races could signal whether a blue wave is materializing.
Taylor Red singer Nicole Taylor dies at 35 4 years after breast cancer diagnosis
Nicole Taylor, a member of the country music band Taylor Red made of identical triplet sisters, has died after being diagnosed with breast cancer in 2022. She was 35.
CHI Health offering personalized ‘Tree of Love’ ornaments to benefit central Nebraska hospital foundations
Community members in Kearney and Grand Island can honor loved ones while giving back to local healthcare initiatives this holiday season through CHI Health’s annual Tree of Love.
Choices, Hope & Science: Years of research, new hope
Diagnosed with cystic fibrosis (CF) at age 3, he grew up during a time when the outlook for many patients was far different than it is today.
Voters on the left and right fear the America they've known is slipping away
Whether they’re from the left or the right, they’re worried that the America they’ve known is slipping away. They see the political class stirring up anger and hate and turning neighbors against each other.
Warnock says he plans 2028 run for ‘high office.’ He doesn’t say which one.
The Senate Democrat from Georgia became the latest politician to land in the conversation about potential 2028 White House contenders.
Inde Navarrette mocks Shane Gillis' gym joke in 'SNL' monologue
Three weeks after Gillis complained about women's workout clothes, Navarrette had a response.
Israeli strike kills boy in Gaza as Qataris say vessel struck in Gulf, and other Mideast news
Israeli strikes on Gaza have killed eight people including a young boy.
BYU, Utah take care of business, setting stage for huge rivalry showdown
The Utes rolled past the Bearcats on the road, while the Cougars held on against the pesky Sun Devils
Join Overtime to talk south Georgia ball with WALB Sports
With an action-packed week in SGA high school football, there is still so much to talk about in Locker Room Report Overtime.
New California Science Center exhibit brings the solar system to audiences
The Samuel Oschin Air and Space Center features a towering space shuttle as well as 100 artifacts and interactive displays.
Mary Black Foundation celebrates 30 years of investing in Spartanburg County
An Upstate grantmaking organization is marking three decades of investing in community health and well-being across Spartanburg County.
‘A Few Good Men’ Broadway review: Tom Blyth turns up the charisma in Tom Cruise’s famous role
Tom Blyth takes on one of Tom Cruise’s most famous film roles in the Broadway revival of Aaron Sorkin’s ‘A Few Good Men’ alongside Bradley Whitford and Krysta Rodriguez. Read EW’s review.
Youth sports coach sentenced for sexually assaulting 12-year-old girl he coached
A youth sports coach has been sentenced to 26 years in prison for sexually assaulting a 12-year-old girl he coached.
Youth sports coach sentenced for sexually assaulting 12-year-old girl he coached
A youth sports coach has been sentenced to 26 years in prison for sexually assaulting a 12-year-old girl he coached.
Youth sports coach sentenced for sexually assaulting 12-year-old girl he coached
A youth sports coach has been sentenced to 26 years in prison for sexually assaulting a 12-year-old girl he coached.
Youth sports coach sentenced for sexually assaulting 12-year-old girl he coached
A youth sports coach has been sentenced to 26 years in prison for sexually assaulting a 12-year-old girl he coached.
Youth sports coach sentenced for sexually assaulting 12-year-old girl he coached
A youth sports coach has been sentenced to 26 years in prison for sexually assaulting a 12-year-old girl he coached.
It's a 'socialist' bank — and North Dakota Republicans love it
Democratic socialist candidates have held up North Dakota's state-owned bank as a model to emulate.
Housing, jobs and a movie theater: What’s in the $43.3M RenCen community benefits agreement
Bedrock LLC and General Motors Co. have agreed to provide $43.3 million in direct community benefits as a condition of their tax incentive request to fund their redevelopment effort of the Renaissance Center.
Illuminated Apple Logo Returns to MacBook Pro After 10 Years
The iconic glowing rear Apple logo is returning to the MacBook Pro with the latest model, Apple today announced. Apple removed the illuminated logo from the MacBook Pro with its 2016 redesign, replacing it with a polished, non-illuminated version. Its return restores one of the laptop's most recognizable design features after a decade. We're glowing with excitement over the new MacBook Pro. You've gotta touch it to believe it.
United-Air Canada joint venture expansion would drive up fares, agency says
Air Canada and United currently account for all nonstop passenger traffic on five of the 10 routes the two airlines want to add.
The Dining Table recommends: The Red Lion Pub
It’s been a gathering spot for actors, writers, locals and, if you believe its lore, ghosts.
New Hampshire political dynasty boosts John E. Sununu in Senate bid
Political dynasty is front and center as Republican John E. Sununu seeks to retake his old Senate seat in a close-fought race against Democratic Representative Chris Pappas.
Vera Health secures $28.5M series A for AI-driven clinical search engine
Clinical artificial intelligence search engine Vera Health secured $28.5 million in series A funding to accelerate and expand its platform. | Vera Health’s platform scans more than 60 million peer-reviewed publications, clinical guidelines, consensus statements and drug labels, executives say.
Israel's elections are wide open. Here's what could decide Netanyahu's political fate.
Pioneering industrial band Ministry is done. Take it from founder Al Jourgensen: 'It's time to go'
Ministry, the pioneering industrial rock band that paved the way for acts like Nine Inch Nails, is calling it quits after 45 years.
Holland Taylor says ‘Two and a Half Men’ ‘never paid me very well,’ even after 4 Emmy noms
Holland Taylor is looking back on her 12-season run on ‘Two and a Half Men,’ during which time, she claims she never got a raise: ‘I loved a lot about that show, but they were not full of courtesies.’
Bethenny Frankel reacts to Bravo ‘b----‘ Andy Cohen’s shady comments about her TikTok
Bethenny Frankel didn’t hesitate to clap back at ‘bitter’ Bravo boss Andy Cohen for his shady comment about her TikTok page.
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
This fifth-generation family business in rural Pa. is making 4,500 brooms for Salem
On Etsy, the Meckleys have made close to 20,000 sales.
He left the CDC to fight RFK Jr. But was it better to fight from within?
Demetre Daskalakis, CDC’s top immunization official, resigned in 2025 to protest Health Secretary Robert F. Kennedy Jr., then became one of his loudest critics.
Join Overtime to talk south Georgia ball with WALB Sports
With an action-packed week in SGA high school football, there is still so much to talk about in Locker Room Report Overtime.
Local business owner faces cleanup after Toledo chemical release
Robert Duling, CEO of Skyline Party Rentals, which is located next to the MC Tank terminal on Progress Avenue, said he’s ready to resume operations.
Businesses worry as part of East Brainerd Road set to close for weekend storm drain work
Drivers planning weekend trips in the Chattanooga area may need to adjust their routes as part of East Brainerd Road is set to close for two days.One business i
3 Subspecialties Gaining Investor and Operator Traction
This is an exclusive BHB+ article. Outpatient mental health services have been the investor darling for nearly a decade. And I don’t see that trend
Main Line Health ups malpractice reserves
Plus, Villanova has 12 interns working in and around the Vatican.
The New Rules of Global Brand Growth
Last week, BoF, ESW and Shopify gathered senior fashion and retail executives from Thom Browne, Reebok, Alo Yoga, Harvey Nichols, Bang & Olufsen and more in London to discuss how brands can win back consumer spend, protect margins and localise in a climate where global growth requires more consideration than ever.
Op-ed: Making sense—and dollars—of resilience
Investments in resilience can strengthen our neighborhoods while creating durable career pathways for the next generation of New Yorkers.
Google Chrome Adds ClickFix Warnings to Stop Users From Running Malicious Commands
Google Chrome adds ClickFix command detection for Enhanced Protection users, warning them before they execute malicious scripts.
Alyssa Farah Griffin shades Meghan McCain with jab at latter’s iconic Joy Behar fight
‘The View’ cohost Alyssa Farah Griffin and producer Brian Teta shaded Meghan McCain in a reference to the latter’s iconic on-air clash with Joy Behar: ‘May have to ask her on air if she missed me.’
First Clade I Mpox case reported in Clark County resident
The Southern Nevada Health District announced Tuesday the first confirmed case of Clade I Mpox in a Clark County resident.
Mississippi Gulf Coast Community College students use AI to solve business problems
Students at the Harrison County campus are learning ways to solve real-world problems using artificial intelligence.
Guided search helps Kentuckians navigate treatment, mental health and recovery resources
A new guided search feature from FindHelpNow.org makes it easier for Kentuckians to find substance use disorder treatment, mental health care and recovery resources that fit their needs.
Experts say election season political talk can affect mental health, relationships
Counselors recommend setting boundaries and leading with curiosity in conversations
Experts say election season political talk can affect mental health, relationships
Counselors recommend setting boundaries and leading with curiosity in conversations
Pearlington residents, business owners push for bridge replacement plan
The Pearlington bridge closed more than four years ago, cutting off a direct route between Pearlington and Louisiana.
Tincher Foundation gift brings record donation to Med Center Health
The Tincher Foundation donated more than $4 million to Med Center Health last month before dissolving in September, part of a gift supporting a program that provides medical and dental care to children regardless of a family's ability to pay.
First Lady announces NIH Women's Health Division
President Donald Trump and First Lady Melania Trump announce an executive order establishing a new Women's Health Division at the National Institutes of Health (NIH) and a White House Women's Health Task Force, followed by an impromptu Q&A session with White House reporters on the South Lawn.
Hackers Exploit Plex2Shell Flaws to Install Crypto Miners and Linux Proxy Backdoor
Attackers exploit four Plex Media Server flaws chained as Plex2Shell to deploy XMRig miners and reverse proxy software after PoC release.
How Science Is Helping Coastal Communities Build Resilience to El Niño
The current El Niño may become the strongest in modern recorded history. The naturally occurring climate phenomenon, primarily associated with persistent, high ocean surface temperatures in the central and eastern tropical Pacific Ocean, could have global-scale effects on weather and ocean conditions through 2027.
Lt. Governor candidate Shawn Oliver suspends campaign after being arrested for allegedly drunk driving
Oliver, a 42-year-old Republican, struck five parked cars along Dartmouth Street in New Bedford just before midnight on Saturday.
ConnectWise Suspends Cloud Backup After Attackers Compromise Microsoft 365 Tenants
ConnectWise disabled seven application identities and suspended Cloud Backup after attackers compromised Microsoft 365 tenants.
Consumer apprehension grows as US retailers adopt AI-assisted pricing tools
U.S. consumers are uneasy about the increasingly high-tech ways that restaurant chains and major retailers are setting prices.
Jenna Dewan’s new ‘DWTS’ dance partner revealed amid Val Chmerkovskiy controversy
Alan Bersten and Jenna Dewan will dance together on ‘Dancing With the Stars’ this week as Val Chmerkovskiy takes a step back from the ballroom following his comments directed toward judge Carrie Ann Inaba.
Addressing mental health proactively for our loved ones
As suicide and mental health concerns continue to impact families and communities, an Atlanta-based mindset expert, Michelle Bryant Johnson, shares how to recognize warning signs, support someone in crisis and navigate grief after devastating loss. You can learn more about SPARK at https://www.michellebryantjohnson.com/spark1000
Political cartoons for October 17
Saturday’s political cartoons include masking mandate, the press secretary, and more
More than $1 million in federal funding headed to rural Wisconsin businesses
More than $1 million in federal funding is headed to rural communities across Wisconsin, including three in southern Wisconsin where officials hope the money will help fill empty downtown storefronts.
Community invited to 5th annual Night of the Living Health Fair
The event will take place from 5:30 to 7:30 p.m. on Friday, October 23 at Rural Health, Inc.'s Anna location.
HOMETOWN ENTERTAINMENT: Comedian Brad Williams bringing his “Tall Tales Tour” to Roanoke
Brad Williams brings Tall Tales Tour to Roanoke this month.
Laredo Health Promotores hosts third annual Halloween Health Fair
The Laredo Health Promotores will host its third annual Halloween Health Fair at El Eden Park on Oct. 17 from 4 to 7 p.m.
Par Health recalls 22 lots of IV blood thinner, its 3rd US product pull in a month
U.S.-based generic drugmaker Par Health has issued
Vermont seasonal businesses try to make ends meet in a short window
From apple picking to finding the perfect pumpkin, business owners rely on customers to make their year-round work worthwhile.
At the Museum of Science's new venue, live music is on the agenda
Jacob Collier, the genre-breaking English polymath, will christen the new museum's new 500-person space with an inaugural performance Friday.
Neil Howard joins Bespoke Sports & Entertainment
Bespoke Sports & Entertainment is augmenting its senior staff, with the hire of Neil Howard as VP experiential. Howard, who was at MKTG from 2006-2025 rising to SVP, working on Toyota and other accounts will be based in Charlotte and become part of Bespoke’s senior leadership team.
Online requests now available for GCHD COMPASS mobile health unit
Visits from the Genesee County Health Department’s COMPASS mobile health unit can now be requested online.
iPhone Duo: Apple Charging $49 for New Cover Layer, $229 for Battery
We just published Apple's list of iPhone Duo repair fees for customers without AppleCare+ coverage, and we want to bring extra attention to two of the fees in particular: a new cover layer costs $49, and a replacement battery is $229. Apple's vice president of hardware engineering Kate Bergeron revealed that the iPhone Duo's nano-texture cover layer above the inner display can be removed and replaced.
Bexar County commissioners back BAMC amid Methodist Healthcare's plans for Level II trauma center
The Bexar County Commissioners Court unanimously approved a resolution Tuesday reaffirming its support for Brooke Army Medical Center’s role in regional trauma care. The vote comes as Methodist Healthcare seeks designation as a Level II trauma facility — a move the court says could affect trauma case distribution and jeopardize BAMC’s mission without coordinated regional assessment.
‘Narnia’ roars to life in rock-infused trailer for Greta Gerwig’s ‘The Magician’s Nephew’
Greta Gerwig brings the origins of ‘Narnia’ to life with a roar from Aslan and a riff from Led Zeppelin in the first trailer for ‘Narnia: The Magician’s Nephew.’
Optum Health surge helps power UnitedHealth Group results
Optum's earnings from operations leaped 48% to $3.7 billion during the third quarter, UnitedHealth Group reported.
Health-related product delivery on the horizon for Ohio State’s Grubhub Rovers
Ohio State Dining Services will partner with the Wilce Student Health Center to potentially use Grubhub Rovers to deliver health-related products to students, with hopes to launch around fall break to combat cold weather-related illnesses. Abby Hertzfeld, senior director of Dining Services, said health product deliveries should launch around fall break, Hertzfeld said. Jason Goodman, […]
Siemens Healthineers doubles down on cardiovascular care as it exits general imaging ultrasound business
The healthcare giant's shift in strategy puts an increased focus on systems used by electrophysiologists and interventional cardiologists to manage and treat cardiovascular disease.
17 new science fiction and fantasy books to read in October 2026
Whether you're looking for scary or cozy reads to put you in the Halloween mood, these new books will do the trick.
A guide to fall festivals and Halloween happenings around Tallahassee
From haunted houses to Greek food festivals, here is your guide to the best fall events in Tallahassee.
Voters have many reasons to be upset
The rising costs of fuel, food, and housing are wearing on people, and the labor market isn't helping, economist Joel Naroff writes.
‘Saturday Night Live’ season 52 recap: Shane Gillis returns to host for third time
‘Saturday Night Live’ season 52 recap: Shane Gillis returns to host for third time (updating live)
iPhone 18 Pro vs iPhone 17: a choice between value and cutting-edge cameras
The Pro is better, yes — but is it right for you?
Oregon Universal Health Plan Group Hastens To Meet Deadline
A few weeks ago, it looked like the board tasked with giving lawmakers the template for government-run universal health care plan would get until December to finish its big report. It turns out it had to move faster.
East Texas Tonight: Dr. Texas Rüegg explains the science behind every sip at Rueggenbach Brewing Co.
In this edition of East Texas Tonight, we learn why Dr. Rüegg went from working in education to opening his own brewery, the challenges of starting your own business, and the science behind every sip!
Google to pull back the curtain on Thompson Center transformation
In an exclusive Crain's event, Google execs will offer a behind-the-scenes look at the high-profile revamp.
Celebrating Ron Hearst: Business owners share thoughts on Ron’s viral shorts moment
For 38 years, he’s tracked the storms so you didn’t have to worry. Friday night, KY3 Chief Meteorologist Ron Hearst retires, capping a career the Ozarks won’t forget.
Analysis | The midterm battle for power in the states
Republicans are on defense in governor and state legislative races.
Nighttime bathroom trips and hidden health issues
Getting out of bed to go use the restroom is common but repeated trips could signal underlying issues. FOX Medical Team's Dr. Mike explains.
CD&R, McKesson acquiring infusion therapy provider Option Care Health for $5.8B
Option Care Health, a provider of infusion therapy services, is being acquired by private equity firm CD&R and healthcare conglomerate McKesson in a deal valued at $5.8 billion, the companies a | Option Care Health, the country's largest independent provider of at-home and alternate site infusion services, would go private in the deal, which is expected to close in the first half of 2027.
Critical Atlassian Flaw Lets Unauthenticated Attackers Read Known Files Across 8 Products
Atlassian fixes a critical path traversal in 8 Data Center products that lets unauthenticated attackers read files if exact paths are known.
'Flew Here Grew Here' talks trending entertainment topics
Olivier Martinez claims Halle Berry assaulted their 12-year-old son, Maceo, alleging she choked him and yelled "Who is dominant now?"
Lawrence Tech launches program to ease automakers’ reliance on rare earth materials
Lawrence Tech's Centrepolis Accelerator and USCAR are partnering to find critical material innovations to make the U.S. auto industry more competitive.
Trump launches ‘Super Intelligence Force’ after calls for AI slowdown
Leaders from the intelligence community, the Pentagon, the Federal Trade Commission and the Office of Personnel Management will serve on the task force.
Clearwater approves Scientology road requests for entertainment center
The council also voted to sell a city-owned parcel for the project this week.
Michael Douglas reveals secret Kathleen Turner romance after lying for 40 years
Michael Douglas reveals in his new memoir that he and ‘Romancing the Stone’ costar Kathleen Turner had a romantic relationship but lied about it for 40 years.
Kentucky flu cases trending up as health departments stock up on vaccines
Statewide flu numbers are trending up slightly, while COVID-19 cases are flattening out after an earlier increase.
Jason Priestley explains why he was No. 1 on the ‘90210’ call sheet: ‘Highest quotes’
Actor Jason Priestley, of ‘Beverly Hills, 90210,’ explains why he and Shannen Doherty were considered the stars of the show.
Disney president weighs in on the future of ‘Jimmy Kimmel Live’: ‘Very challenging’
Disney president Dana Walden weighs in on the future of Jimmy Kimmel’s talk show and late-night television as a whole.
Carolina Hurricanes games come to Palmetto Sports & Entertainment Network!
National Hockey League’s Carolina Hurricanes, today announced that the team has partnered with Gray Media to simulcast 10 Hurricanes Hockey Network game broadcasts over the air in markets throughout the Carolinas.
Johnson & Johnson survey finds women not connecting menopause to eye health changes
Hot flashes, mood and sleep disturbances are common themes for menopause: But vision changes are not as well recognized on the list of common symptoms. | Hot flashes, mood and sleep disturbances are common themes for menopause: But vision changes are not one that makes the list of common symptoms. Now, J&J is looking to highlight this often-overlooked issue.
Trump says he discussed release of political prisoners with Xi
US President Donald Trump said on Wednesday he discussed the release of political prisoners with Chinese President Xi Jinping when the two leaders met last week.
Carle Health to host Camp Healing Heart
The event features therapeutic sessions interspersed with camp activities, hayrack rides, a climbing wall and arts and crafts.
New study warns about health dangers of plastics
A new study is out warning about the potential dangers of plastic.
‘GMA’ personality Will Reeve shares emotional update on health after cancer diagnosis
‘Good Morning America’ personality Will Reeve gave an emotional update on his health after revealing his testicular cancer diagnosis: ‘I worried about being a burden,’ he explained on ‘GMA.’
Morningstar joining Google at Thompson Center
The financial services firm will anchor the building alongside Google with the largest downtown office lease inked this year.