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Northern Michigan University banks on new business school, housing to help boost enrollment
The university in Marquette is undertaking several initiatives to help reverse a decade-plus enrollment slide.
Fortune Most Powerful Women Summit in Goleta Focuses on AI, Leadership and the Future of Business
Leaders gather on the Central Coast to discuss technological change, women's representation in business and solutions to community challenges. GOLETA,
The real cost of payroll: A small business guide for 2026
Setting up a payroll system can feel like a steep climb if accounting isn’t your strong suit, but it’s the backbone of your business's health. In fact,
South Coast Business & Technology Awards help fund opportunities
SANTA BARBARA, Calif. (KEYT) The networking reception and the South Coast Business & Technology Awards at the Hilton Santa Barbara Beachfront Resort
Merck’s cholesterol pill gets US FDA approval
Merck said on Thursday the U.S. FDA has approved its cholesterol pill, the first of its kind to receive the health regulator’s nod, bolstering the drugmaker’s efforts to diversify beyond its blockbuster cancer treatment Keytruda.
Girding against Keytruda cliff, Merck splits oncology into standalone business unit
The patent cliff for Keytruda is fast approaching in the U.S. Now, as Merck & Co. | The patent cliff for Keytruda is fast approaching in the U.S. Now, as Merck & Co. increasingly looks to life after its oncology megablockbuster, the company is honing its focus on new and upcoming medicines by splitting its core pharmaceutical business in two.
Santa Barbara Museum of Natural History Celebrates National Earth Science Week
SANTA BARBARA, Calif. (KEYT) — Fossils, minerals and discoveries about our planet will take center stage at the Santa Barbara Museum of Natural History
Santa Barbara Museum of Natural History Celebrates National Earth Science Week
SANTA BARBARA, Calif. — Fossils, minerals and discoveries about our planet will take center stage at the Santa Barbara Museum of Natural History during
Do business plans work? Here's what the data actually says
New business owners often face the same dilemma: spend time writing a business plan, or spend a week finding their first customers. So which one actually
Today’s Papers – Pride and redemption as Italy bounce back
La Gazzetta dello SportRonaldo’s sunset: he finds himself on the benchFlower of ItalyAzzurri relaunch, goals and beautiful playing style in TurkeyThe revolution works. Pio and Seba Esposito together...
SLO County Public Health Confirms First Measles Case of 2026
Below is a press release from The County of San Luis Obispo Department of Public Health regarding a confirmed case of measles. SAN LUIS OBISPO, Calif. —
501 small business owners’ biggest regret
What’s the number one regret small business owners have in their first year of business? According to an ERGO NEXT survey of 501 business owners
A new cancer vaccine may keep melanoma from coming back
A personalized mRNA vaccine paired with Keytruda may help keep skin cancer from returning after surgery, a large clinical trial suggests.
A ‘burgeoning black market’, inflated dosing and the over-judicialization of health care: reporters around the world tell stories about Keytruda
In a yearlong investigation led by the International Consortium of Investigative Journalists, reporters from more than 37 countries found the cancer drug’s high price impacts patients and health systems differently.
Santa Barbara pumpkin patch sees slower business ahead of Halloween
SANTA BARBARA, Calif. — Halloween is approaching, but business at Lane Farms has been slower than usual as recent heat and changing weather affect visits
Is 50 the new 60?
Subscribe TL;DR: Younger generations are showing signs of worse health compared to earlier-born cohorts at the same age This backward “drift” is showing up both in mortality risk and chronic disease Worsening trends in obesity and diabetes are the most consistent signals Taking the long view, we’ve made astonishing gains in health and life expectancy in the last century. Global average life expectancy has more than doubled from 32 years in 1900 to 73 years in 2024. (But don’t forget, there were still old people when life expectancy was 32). As people lived longer, they also generally lived healthier along the way. It turns out that avoiding things that can kill you early, like malnutrition and lots of childhood infections, also keeps you healthier later in life. In a classic 2004 paper, Finch and Crimmins proposed that cohorts of children who benefited from fewer early life infections had less lifetime exposure to inflammation and cardiovascular disease later in life, accelerating mortality improvements at older ages. Poor nutrition in the womb has also been linked to a higher risk of later chronic disease. The upshot is that improvements in childhood health can pay dividends many decades later. The combination of better living conditions (nutrition, sanitation) and medical advances (antibiotics, vaccines, blood pressure meds, etc) meant that people’s healthy lifespan generally expanded, even as they lived longer. Aging researchers call this best-case scenario “compression of morbidity”—meaning we delay the onset of disease and disability even faster than the years of life we are adding. During my 20+ year research career, we could generally bank on the idea that younger generations would not only live longer but also keep getting healthier along the way. “60 is the new 50” as they say… Enter “Generational Health Drift” Sadly, this expectation of steady progress may be changing. You’ve probably heard that US life expectancy gains have slowed to a crawl in the past couple of decades. Mortality improvements are also slowing (though less dramatically) in many other high-income countries (you can read more about that in a review paper I wrote here). Mortality is a very blunt health measure, but it is often a good barometer for the broader population health trends happening underneath. And we are now seeing that younger generations may be in worse health at similar ages compared to earlier born cohorts. My collaborator Prof. George Ploubidis at University College London coined this worsening health in more recently born cohorts “generational health drift.” “Generational health drift” is bad news on multiple fronts. Most obviously, we don’t want our health progress to go backward. But the timing is also bad, since our populations are aging. In demographic terms, “population aging” means that the proportion of the population at older ages (i.e >65 years) is increasing. Fun demography fact: Current population aging is not due to the recent declines in the birth rates making the news, but declines in fertility decades ago, after the “baby boom.” As baby boomers reach older ages, the smaller cohorts behind them mean the percentage of older adults will increase. For example, the share of the population age 65 and older in the US increased from 12.4% in 2004 to 18.0% in 2024. This story of population aging was written long ago. Many worry that population aging will put pressure on health care and pension systems. But if people reach older ages in better health than in years past, those fiscal pressures would be less dire than projected. Healthy older people can also continue to contribute to society in many valuable ways, including paid work, caregiving, community service….even high political office 🤷. On the flip side, if younger generations reach retirement age in worse health and with more disabling conditions, this could magnify the societal challenge of population aging. Evidence for worsening generational health A recent paper that I LOVED in the Proceedings of the National Academy of Sciences by Dr. Leah Abrams and colleagues examined which birth cohorts (aka generations) were behind worsening US mortality. Behold the Lexis diagram (cue swooning demographers). Calendar time is on the x-axis, age on the y-axis. Birth cohorts can be followed over time as they age on the diagonal lines moving up and to the right. This figure plots the year-on-year % change in all-cause mortality at a given age. Green shading indicates mortality improvements over time, white is stagnation, and gray shading indicates worsening mortality. Following the diagonal line for those born in 1950, you can see a noticeable shift from green to gray that follows this cohort for most of their lives. This gray shading shows generally worsening mortality for the 1950 to 1959 birth cohorts compared to their predecessors across all ages. Concerningly for my GenX and elder millennial peeps, there was also a deterioration in mortality for birth cohorts born in the 1970s and 1980s, visible as dark gray areas at ages 30 to 45 during the 2010s. While some of these mortality changes reflect specific shocks such as the opioid epidemic, most deaths still occur from major causes of death such as cardiovascular disease and cancer. For cancer, the gray in the top left corner of the figure below reflects the legacies of smoking for older cohorts, followed by a period of green with improvements in cancer mortality as smoking rates declined. But the white/gray shading in the bottom right corner highlights a stagnation and reversal of the cancer trends, with cohorts born around 1970 to 1985 experiencing worsening cancer mortality. This deterioration was most noticeable for colon cancer mortality, possibly linked to obesity or dietary factors. Not just dying more, but less healthy along the way. A recent paper by Dr. Laura Gimeno of University College London (of which I am a co-author), found evidence that more recently born cohorts in Great Britain have stagnating or worsening health. A stylized picture of what“generational health drift” might look like: The review paper found: Rates of childhood overweight and obesity were highest among Gen Z. Rates of diabetes in the 40s almost doubled from 3.1% among the Baby Boomers to 5.9% in Generation X. Gen Z reported higher rates of poor mental health in adolescence compared to earlier-born groups. These UK results are consistent with studies showing worsening health across generations in the US as well. A 2021 US study found that more recently born cohorts had worse biological markers (like blood pressure and blood sugar) than earlier generations at the same age. A separate 2022 study of Americans aged 50 and over found that more recently born generations had a higher number of chronic diseases, with younger age of disease onset. A 2024 Lancet paper found that in the US, women born in 1945 had 33% obesity prevalence at age 50, rising to 48.2% for women born in 1970 turning 50. So what’s going on, and can we turn it around? We don’t have a definitive answer for what’s causing the deteriorating health of younger cohorts, but circumstantial evidence points to worsening trends in obesity and diabetes in both the US and UK. Remember that cohort trends reflect lagged effects of early environments, and younger generations have faced both earlier onset and more severe obesity across their lifetimes. Despite these very concerning trends, the future is not set in stone. We’ve reversed poor generational health trends before: drops in smoking are a major reason cancer and heart disease deaths fell so dramatically in recent decades. GLP-1 drugs may finally turn the tide against rising rates of obesity and diabetes, though it is still early days. But things could also get worse…for example from a return to higher levels of childhood infectious diseases that can have a lasting impact on health. See for example: [ ](https://jenndowd.substack.com/p/dont-you-forget-about-measles-the) [ Don’t You Forget About Me(asles): The Virus That Erases Immune Memory ](https://jenndowd.substack.com/p/dont-you-forget-about-measles-the) Jenn Dowd, PhD · March 24, 2025 [ Read full story ](https://jenndowd.substack.com/p/dont-you-forget-about-measles-the) Even as an optimist, emerging data on the “generational health drift” has my full attention. For most of my research career, we took it for granted that each generation would be healthier than the last. But if present trends continue, **50 could be the new 60….**and Gen Z celebrities will soon look older than Paul Rudd :). Stay well, Jenn Share the Health! If you found this post useful, please share it with a friend. Share
Character matters most in politics
Pat Hickey writes: Nevadans do not need political messiahs or prophets of partisan doom to save us from the evils of the other political party.
24th Congressional District Candidate Changes Political Status
SANTA BARBARA COUNTY, CA (KEYT) - Bob Smith, the congressional candidate hoping to unseat incumbent congressman Salud Carbajal, is no longer aligned with
Merck to create separate cancer business to offset Keytruda patent loss, WSJ reports
Drugmaker Merck is separating its human-health business into two divisions to offset pressures related to the patent loss of its top-selling drug Keytruda, the Wall Street Journal reported on Monday.
First Ever Nite Life Car Show Expected to Boost Business in Downtown Santa Barbara
SANTA BARBARA, Calif. (KEYT) - Downtown Santa Barbara will have some new horsepower Sunday. The NITE LIFE car club of Santa Barbara presents its first car
Cumberland Schools Consider Adding Two New Sports
The district could introduce women’s flag football and men’s volleyball during the 2027-28 school year.
Running a small business means making sacrifices. Are they permanent?
Small business ownership means sacrificing time, predictable income, and sometimes even your own paycheck to build a business. Those sacrifices can become
Merck to create separate cancer business to offset Keytruda patent loss
Merck said on Monday it will split its human-health business into two divisions, separating its cancer franchise from its non-oncology medicines.
Is Britain becoming ungovernable?
Difficult trade-offs ahead require a leader who can ‘switch off all the noise and fixate on the real problems’
Kayla Keyt Testifies on Family Business and Defendant Caleb Flynn
Kayla Keyt testifies about her family's commercial flooring business, her late sister Ashley, and the financial projections she shared with the defendant, Caleb Flynn.
Santa Barbara Workshop Shows Business Owners They Don't Have to do it Alone
SANTA BARBARA, Calif. (KEYT) — For many small business owners, handling and making decisions is a one-man show. A Santa Barbara workshop will look at how