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Iowa State falls at No. 8 BYU

PROVO, Utah — Iowa State (3-3, 1-2 Big 12) dropped a 24-10 decision to the No. 8 Brigham Young (5-0, 3-0 Big 12)Friday night. Cyclone quarterback Jaylen Raynor completed 16 of 29 passes for 98 yards and a touchdown in the loss. His two favorite targets were Ty Claiborne, Tyler Fortenberry and Omari Hayes who […]

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Oct 10 • 2:03 AM EDT • Sports • sports.yahoo.com
The Pivotal Change that Fixed the Browns Defense

After a disastrous opening blowout, Mike Rutenberg scrapped his zone-heavy, Week 1 scheme to get the Cleveland Browns defense back to playing their brand of football. They're 3-0 since the switch.

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Oct 9 • 9:27 AM EDT • Sports • sports.yahoo.com
The Wall Street Veteran Trying to Solve the Pentagon’s Missile Problem

In his first interview on the job, Deputy Secretary of Defense Steve Feinberg, a private-equity billionaire, defended his unusual approach.

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Oct 8 • 7:00 PM EDT • Politics • wsj.com
Hot Sardines will return to Weinberg with vintage jazz

The Hot Sardines, a revivalist jazz band that emerged from Brooklyn’s underground party scene, will bring its reinvigorated take on classic jazz back to the Weinberg Center for the Arts

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Oct 6 • 8:33 AM EDT • Entertainment • fredericknewspost.com
The AI Advantage Minnesota Has Been Building for Decades

Software companies used to defend themselves in a handful of reliable ways. They built useful features, made their products easy to use and counted on the hassle of switching platforms to keep their customers from leaving. A new company that wanted to compete had to invest months, sometimes even years, of engineering time to catch

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Oct 5 • 7:46 AM EDT • Business • tcbmag.com
How gaming store owners turned hobbies into businesses

Explore how local owners Mike Butkus and Tony Vandenberg turned a passion for gaming into successful businesses in the Upper Valley.

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Oct 4 • 11:58 AM EDT • Business • vnews.com
Aaron Sorkin says ‘money does not motivate’ Jesse Eisenberg: ‘It’s infuriating’

Aaron Sorkin says he spent three days trying to convince Jesse Eisenberg to return as Mark Zuckerberg for ‘The Social Reckoning,’ but none of his arguments, including a substantial salary, made an impact on the star.

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Oct 3 • 9:00 AM EDT • Entertainment • ew.com
Colorado is passive-aggressive with business

Colorado has a strange brew of economic policies

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Oct 2 • 7:00 AM EDT • Business • denvergazette.com
Massive Ryan Gravenberch worry coming out, Liverpool have a problem

Liverpool have a problem here. There's a massive worry coming out with Ryan Gravenberch and it threatens to disrupt the Reds' plans.Ryan Gravenberch was on top of the world in 2024/25. The midfielder ...

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Oct 2 • 1:40 AM EDT • Sports • sports.yahoo.com
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Politics doesn't always 'reward what it should': Brian Brenberg

'The Big Money Show' panelists analyze economic data, GDP growth and President Donald Trump's manufacturing push in Texas.

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Oct 1 • 3:32 PM EDT • Politics • foxbusiness.com
New Fox Business Network FBN Lineup Replacing Maria Bartiromo

FBN will replace Bartiromo's old timeslot with 'Big Money in the Morning,' with new co-hosts for the lunchtime program and Li Claman adding a Friday evening program.

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Oct 1 • 11:25 AM EDT • Business • hollywoodreporter.com
Access to cancer care in rural Wisconsin makes a difference

After breast cancer was found during Katie Weinberger's routine mammogram, her community and care team stepped up.

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Oct 1 • 9:00 AM EDT • Health • news.sanfordhealth.org
Protect College Sports Act moves to the House

The act would regulate college sports at the federal level.

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Sep 29 • 8:36 PM EDT • Sports • uscannenbergmedia.com
Jon Watts reportedly set to direct the next 'Star Wars' film

Watts would direct the first of Simon Kinberg's planned Skywalker Saga trilogy, though Disney hasn't greenlit it, THR reports.

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Sep 27 • 11:28 AM EDT • Entertainment • mashable.com
Sharks Rookie Already Turning Heads After Two Preseason Games

Fans of the San Jose Sharks have got to love what they are seeing in rookie Ivar Stenberg. The second-overall pick in the 2026 NHL Entry Draft has already recorded five points, three goals, and a plus-3 across his first two preseason games, generating even more optimism for one of the league’s brightest up-and-coming hockey […] The post Sharks Rookie Already Turning Heads After Two Preseason Games appeared first on HEAVY.

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Sep 26 • 1:21 AM EDT • Sports • sports.yahoo.com
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The AM Sports Rundown

The sports news we missed from the week of September 21.

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Sep 25 • 7:30 PM EDT • Sports • uscannenbergmedia.com
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Capt. Sully reveals greatest concern amid Alzheimer's battle

Capt. Chesley "Sully" Sullenberger III is opening up about what lies ahead for him and his family after his recent Alzheimer's disease diagnosis.

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Sep 24 • 11:08 AM EDT • Entertainment • centraloregondaily.com
'The Debut' review: Julianne Moore becomes an Oscar contender with Jesse Eisenberg's outrageous theater farce

If you love "Only Murders in the Building," you'll adore "The Debut."

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Sep 23 • 5:00 AM EDT • Entertainment • mashable.com
The potential local impact of Spanberger's data center 'framework'

Gov. Abigail Spanberger released her blueprint for regulating data center development last week, billing it as “a new way forward for how this industry does business in the Commonwealth.”

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Sep 22 • 7:45 PM EDT • Business • loudountimes.com
907 Sports: High school football playoffs draw closer

On this episode of 907 Sports, Charlie Fellows dives into Week 6 high school action from across the state, as the playoffs are just two weeks away. Plus, Jordan Rodenberger joins the show to talk NFL Week 2!

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Sep 22 • 12:11 AM EDT • Sports • alaskasnewssource.com
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Sen. Gary Peters appointed new Center for the Political Future director

The Michigan lawmaker plans to expand CPF’s activities at USC’s Capital Campus in Washington, D.C.

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Sep 21 • 8:31 PM EDT • Politics • uscannenbergmedia.com
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Transformative Biological and Environmental Frontiers: Synthesizing the 2026 Tang Prize Science Laureates

The Tang Prize in Sustainable Development and Biopharmaceutical Science honors pivotal scientific advances that improve global health, restore damaged ecosystems, and deliver transformative medical treatments. The 2026 science laureates, Professor Susan Solomon for Sustainable Development, along with Dr. Steven A. Rosenberg, Dr. Michel Sadelain, and Dr. Carl H. June for Biopharmaceutical Science, demonstrate how disciplined

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Sep 21 • 6:19 AM EDT • Science • geneonline.com
Iowans, business owner react to Sunday's flooding in Marion, Cedar Rapids

KGAN CBS 2 and KFXA Fox 28 provide local news, weather forecasts, notices of events and items of interest in the community, sports and entertainment programming for Cedar Rapids and nearby towns and communities in the Corridor and throughout eastern Iowa, including Iowa City, Waterloo, Dubuque, North Liberty, Coralville, Marion, Morengo, Williamsburg, Washington, Tiffin, Tipton, Solon, Mount Vernon, Lisbon, Central City, Urbana, Independence, Manchester, Dyersville, Oelwein, Cedar Falls, Waverly, Evansdale, Guttenberg, West Union, New Hampton, Decorah, Waukon, Maquoketa, Sigourney, Fairfield, Grundy Center, La Porte City, Dysart, Fayette, Elkader, Strawberry Point and Belle Plaine.

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Sep 20 • 10:23 PM EDT • Business • cbs2iowa.com
Confirmed 2. Bundesliga lineups: Hannover 96 vs. VfL Bochum

Interim head coach Lars Barlemann makes two changes from the defeat in Nürnberg. Franz Roggow and Benjamin Källman replace Waniss Taïbi and Benedikt Pichler. Uwe Rösler makes one change from the ...

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Sep 20 • 6:38 AM EDT • Sports • sports.yahoo.com
Science on Tap: Mechanics of Messaging

A monthly series of informal discussions by the SEE Science Center on relevant topics with local experts and scientists. Doors open at 5pm. Events are free. Advance Sign up appreciated. Food and drink can be ordered off the menu.Oct. 13 Topic: Mechanics of MessagingWe all know that Gutenberg changed the world, but printing technology did not stop there. Join us to discuss how NH has played a role in the evolution of high-tech printing and related technologies. From Dot-Matrix, to Ink jet to Laser and 3-D discover what is being employed, how it evolved and where it is headed next.Panelists will include:James K McMahon- Layer Grown Model Technology Services-Retired

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Sep 19 • 6:47 PM EDT • Science • nhpr.org
Spanberger bans by-right approvals, NDAs for data centers

Gov. Abigail Spanberger unveiled a data center accountability plan and and an executive order that includes creating an AI task force.

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Sep 18 • 12:25 PM EDT • Business • virginiabusiness.com
Virginia tightens data center restrictions amid political backlash

The U.S. state of ​Virginia is tightening ‌controls on data centers, with plans that ​include banning non-disclosure ​agreements for the projects, ⁠requiring stricter permitting ​and imposing clean energy ​mandates on the server warehouses, Governor Abigail Spanberger ​said on Friday.

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Sep 18 • 11:42 AM EDT • Politics • reuters.com
Harwich cranberry festival features drone show, cider and music

The 50th Harwich Cranberry Arts and Music Festival returns this weekend with a drone show, live music, and crafts.

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Sep 18 • 6:03 AM EDT • Entertainment • capecodtimes.com
Keep or sell Cherki? FPL gameweek five dilemmas

BBC Sport's Fantasy Premier League expert FPL Heisenberg gives his answers to some of the biggest dilemmas facing managers in gameweek five.

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Sep 18 • 2:44 AM EDT • Sports • sports.yahoo.com
Viewpoint: Let's take dark money out of Montana politics

John Westenberg writes, I realize money will always play a role in politics. I’m convinced, however, that a huge step can be taken to make that money “honest”

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Sep 17 • 10:34 AM EDT • Politics • missoulacurrent.com
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2. Bundesliga Preview: Karlsruher SC vs. 1. FC Nürnberg

Nürnberg will hope to bolster their promotion hopes with three points from Karlsruhe just before the extended international break. The visitors have only dropped points once this season – the 2-2 d...

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Sep 17 • 4:00 AM EDT • Sports • sports.yahoo.com
‘CSI’ alum Marg Helgenberger joins ‘Blue Bloods’ spinoff in guest role as Maggie Lawson’s mother

‘CSI’ star Marg Helgenberger is returning to CBS for a guest role on the upcoming season of the ‘Blue Bloods’ spinoff ‘Boston Blue.’ The actress will play the estranged mother of Maggie Lawson’s Sarah Silver.

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Sep 16 • 6:15 PM EDT • Entertainment • ew.com
What Does the Science of Climate Change Really Look Like?

Editor’s Note: This is the second in a three-part series on how the Right should think about environmental and climate policy. Read Chris Barnard on Reclaiming Environmental Policy from the Left. More than a decade ago, the world’s governments negotiated and signed the Paris Climate Agreement, committing to hold global warming well below 2 degrees Celsius. In the following years, climate had immense cultural power. Greta Thunberg emerged. Fortune 500 companies established net-zero plans. The U.S. got the Inflation Reduction Act. Then the pendulum swung back. President Donald Trump returned to the Oval Office, speaking of green energy as a “scam” and carbon footprints as a “hoax” and on all matters of international policy emphasizing bilateral engagement and power over globalism and cooperation. The technology companies that had been at the forefront of net-zero pledges and green leadership discovered the importance of all-of-the-above power to their visions for artificial intelligence and began quietly postponing or removing their targets. On the left side of the political spectrum, rising concerns about inflation and cost pushed climate lower down in the stated priorities of voters and stump speeches of politicians. The moment is ripe for a reset on the politics of climate change and for conservatives especially to chart a course that acknowledges and addresses the real challenges in plausible ways. So what should we think about climate change as we enter a post-peak climate era? If it is neither an apocalypse nor a hoax, what will hold up as a durable view of climate change? And how does it project onto the concerns and priorities of the right-of-center’s emerging coalition? New to Commonplace_? Subscribe below to get the magazine in your inbox._ Subscribe A Solid Foundation As the politics and economics of climate careened over the past ten years, the physics carried on regardless. In 2015, the year the Paris Climate Agreement was adopted, the world emitted 41.2 gigatonnes of carbon dioxide. By 2025, emissions had risen only 2.4%, to 42.2 gigatonnes, because falling emissions from land use offset increasing emissions from fossil fuels. But slow growth in annual emissions is not rapid decline, let alone net-zero, so carbon dioxide kept accumulating in the atmosphere, going from 399 to 426 parts per million. Global temperature kept rising too, from about 1.1 degrees Celsius above the 1850–1900 average in 2015, to 1.4 degrees above it in 2025. None of this should surprise anyone. Even most prominent skeptics, like the authors of the 2025 report commissioned by the Trump administration’s Department of Energy, accept the basic physics. Carbon dioxide added to the atmosphere at industrial volumes accumulates and traps heat that would otherwise escape to space. That heat warms the upper ocean and increases temperatures at the surface. Increased ocean heat and melting of land ice cause sea levels to rise. Changes in the climate become noticeable to us as subtle shifts in temperature and precipitation, seasons arriving early or late, changes in the surrounding ecosystem, and weather extremes. The much more meaningful debate is not about whether these things are happening, but about what it all means for human societies. (While it is a proxy measure of overall risk, no one experiences global surface temperature.) This debate invokes at least three interesting questions: how much today’s warming is showing up in regional climate trends, how much more warming we should anticipate, and how extreme weather events can be understood in the context of climate change. Recent scientific advances give us new insights into each of these, but there is still much to learn. This is the context in which the next generation of conservative leaders will be the first to deal with significant climate change as a fact, not a forecast. It will be with them for their entire careers. Our evolving scientific picture of climate change will come from weather and climate records stretching further into the past, new kinds of observations in the present, better modeling tools for the future, and simply more time to observe the emergence of climate signals and their tangible effects on ecosystems and communities in the United States and around the world. The policy landscape will be shaped by not only the impacts of changes in the climate, but also by the ways in which societies respond and by the emergence of new technologies for both altering the trajectory of emissions and adapting to new climate realities. Global climate records now show the fingerprints of warming in different phenomena around much of the world. The IPCC, in its most recent assessment report, documents warming trends over all land regions, even as natural variability adds substantial variance to local trends. And the highest temperature extremes have become more intense and frequent, almost everywhere, since the 1950s. Scientists are highly confident that these changes are attributable to human influence. But confidence in detecting trends and attributing them to human influence degrades across heavy precipitation events; drought trends are heterogeneous and not attributable to human activity with great confidence. For hurricanes, tornadoes, and other severe storms there is even less confidence in trends or their relationship to climate change. In general, a fair summary of the evidence is that for well-observed phenomena, like surface temperature or heavy rainfall, with a clear relationship to warming, our multidecadal observations are consistent with human influence overcoming natural variability over long time periods and extremes increasing. For regions that are sampled more sparsely, or phenomena with a higher noise-to-signal ratio, we will need to observe them longer to understand the magnitude of the climate signal or improve dynamical understanding using models and observations together. But for Climate For those who can’t wait, we also have new techniques that attempt to understand the role climate change has in influencing particular extreme events. When the climate is changing and disaster strikes, it is natural to ask whether that disaster was somehow “caused” by climate change. For scientists and policymakers acting in good faith, answering that question helps develop a more accurate picture of the problem, how it may be getting worse, and what preparations we should be making to respond to it. It may, at some point, give some weight to how liability is assigned by courts or adaptation funding is distributed by society. But how we ask this question is extremely important. It is easy to get the analysis wrong by discounting the role that meteorology plays. As meteorologist Theodore Shepherd explained in a clear 2016 review of climate attribution methods, “if a weather or climate event is truly extreme in the present climate, then perforce it requires unusual meteorological conditions, which means that climate change is at most a contributing factor.” Share Scientists have two ways to probe climate as a contributing factor, both of which have entered media coverage of extreme weather events. One asks a probabilistic question: How much more likely is a particular event (e.g., a temperature record over a particular area) amid global warming? The answer involves using historical records and computer simulations to estimate the likelihood of such an event in both a changed and a preindustrial climate. The findings are less about the specific event, and more about events of that nature. The other question is: How has the changed climate affected the specific event in question? Here, scientists try to understand what a similar event would have looked like in the preindustrial climate. This is sometimes called the storyline approach, where the story is the specific meteorological details of the event. These methods offer ways to test the intuition of scientists about real weather extremes. In late June and early July of 2021, a persistent high-pressure ridge, or heat dome, set up over the Pacific Northwest and an extraordinary heat wave affected the area from Oregon to British Columbia. For six days, it shattered temperature records across the region and hundreds died from heat-related causes, in an area where such high, and persistently high, temperatures were well outside of experience and many live without air conditioning. Scientists have studied its connection to climate change using multiple approaches. This specific event was created by a rare combination of meteorological factors, a strong high-pressure ridge created the conditions for extreme heat, which occurred on top of higher average temperatures in the region from global warming. Probabilistic analyses showed that climate change increased the likelihood of such an event by at least 8-fold to more than 100-fold. One standout example found that such an event had effectively zero probability of occurring in the preindustrial climate. The enormous range in these assessments reflects how hard it is to estimate probabilities of events at the tail of the historical record. Estimates of the effect on the temperature of the event are more clustered. A recent review paper documents how multiple methodologies have found a positive influence, roughly 1-2 degrees Celsius of an anomaly that exceeded 15 degrees, of climate change on the temperature magnitude of the event. Multiple studies have investigated and found some positive influence of climate change in other extreme events. Attribution studies found climate likely increased the heavy rainfall that accompanied Hurricane Helene in North Carolina and surrounding regions in 2024. The extensive fires that struck Los Angeles in 2025 illustrate how the causal chain can become messy, though. Studies do detect a positive influence of climate on the event’s likelihood, but while climate change likely contributed to underlying aridity, it would not have played a role in the heavy winds or land practices that preceded disaster. These event attribution studies will become more common for extreme, or damaging, weather events. They can be produced quickly, and often are reported before peer review. As the Pacific Northwest heatwave example shows, when multiple methods converge on a positive attribution, the finding should probably carry some weight even if you have to be careful about accepting the results from a single study. I expect that as climate change proceeds and the climate thus departs further from a preindustrial counterfactual, the influence will become more detectable across a variety of extreme events and more easily identified. This will be used to cast blame, but can also be used to inform how communities and society adapt to ongoing change. We May Still Be Surprised One positive development, insofar as less climate change is better, has been that our central estimates for future climate change should probably be revised downward. Mostly, that is because the high-end warmings that scientists regularly analyzed about ten to 20 years ago, driven by high emissions throughout the twenty-first century, now appear to be somewhere between unlikely and impossible. At one time, the upper end of mainstream climate projections extended well into 4 to 6 degrees Celsius of warming by the end of this century, which, models suggest, would have wrought enormous real-world damage. Current energy and policy trends now point toward 2.5 or 3 degrees. Damages and risks are commonly modeled as increasing steeply with more warming, so this is already a better-than-previously-expected outcome for the climate (which is independent of the physical response to emissions). But we should maintain a wide range for plausible outcomes and prepare for the possibility of being surprised. Emissions trajectories are subject to deep uncertainty, the physical climate response is still developing, and whatever change occurs in the climate will then be mediated through unpredictable economic, social, and political institutions. Over the past decade, the pace of warming surprised some keen observers and appeared to accelerate, though not yet outside the range of expectation provided by climate models. The reasons for that apparent acceleration are being actively studied (as was the apparent pause in warming from 1998 to 2012), but no single driver has emerged. Some blame it on the El Niño, variability which would have no bearing on climate. Some think it is a result of factories in East Asia and global shipping fleets cutting aerosol emissions, which in the strongest version of the argument would indicate higher climate sensitivity to carbon-dioxide emissions. Others are more measured, not yet ready to draw solid conclusions as to whether climate projections require revision. We will have to see. Long-Term Thinking Climate change asks us to think over long time scales. But the pace of human-driven warming is compressing a large global change into a century. Changing weather patterns and extreme events are already causing adjustment costs and damages and will do more. Adaptation will help, but it is not free. For some communities, these costs will erode livelihoods and well-being, and may force migration. Are we prepared for large-scale managed retreats in the United States? Thankfully, American wealth, geographical diversity, and moderate climates may leave us better prepared than many around the world. But wealthy countries can still suffer serious disruption from narrowly concentrated costs, even if they appear entirely manageable in aggregate. Readers of Commonplace are familiar with the challenges of rapidly adapting to economic forces. The displacement that came from the China Shock is barely perceptible in aggregate GDP and employment data, but it affected millions of people and those people were far less mobile than economic models tended to assume. Deindustrialization rippled through the nation with enormous effects for not only our economic vitality, but also our national security. The forces surrounding climate change may not be so different; the world gets richer and must accept some diffuse costs. Those may be modest overall, but cause all manner of unpredictable effects with which policymakers must cope. In the case of the China Shock, our faith in a growing pie served us poorly. We’ll need to do better on climate. Leave a comment

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Sep 16 • 4:30 PM EDT • Science • commonplace.org
Julianne Moore, Paul Giamatti admit past costars have ‘gone nuts’ and ‘off the deep end’ on movie sets

The pair premiered Jesse Eisenberg’s new movie “The Debut” — about an actor’s wild creative process — to uproarious applause at TIFF.

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Sep 14 • 10:24 AM EDT • Entertainment • yahoo.com
Jack’s Daily: Blackhawks Battle Blues; Byram Talk; Stenberg Scores Two

The Chicago Blackhawks three-day Rookie Camp is officially a wrap, and now it’s time to begin the two-game prospect showcase […] The post Jack’s Daily: Blackhawks Battle Blues; Byram Talk; Stenberg Scores Two appeared first on Chicago Hockey Now.

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Sep 14 • 10:08 AM EDT • Sports • sports.yahoo.com
Podcast: Hockey on the Horizon

After a long, hot summer, the return of Pittsburgh Penguins hockey is just days away with training set to open this Thursday at the UPMC Lemieux complex in Cranberry. There will be just three days of practice for the Penguins before preseason action opens a week from today, September 21st, against the Buffalo Sabres at […]

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Sep 14 • 6:00 AM EDT • Sports • sports.yahoo.com
Liverpool take first step towards deal for new Ryan Gravenberch

Liverpool have their eyes on a new Ryan Gravenberch. They've registered their interest - and things could move quickly from here.2027 will largely be dominated by Liverpool trying to find a new midfie...

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Sep 12 • 5:40 AM EDT • Sports • sports.yahoo.com
Liverpool eye move for their next South American sensation

At the moment, Alexis Mac Allister's future is completely up in the air. The Argentinian hasn't been offered a new deal by Liverpool despite both Ryan Gravenberch and Dominik Szoboszlai both being han...

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Sep 12 • 2:35 AM EDT • Sports • sports.yahoo.com
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Shane Lowry seizes Irish Open lead after course-record 62

Shane Lowry scorched the links at Doonberg to take the lead on Day 2 at the Amgen Irish Open.

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Sep 11 • 4:01 PM EDT • Sports • sports.yahoo.com
Anthony Bagnuola

Anthony Bagnuola is a shareholder in Greenberg Traurig’s Long Island office.

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Sep 11 • 1:00 AM EDT • Business • libn.com
Joshua M. Liebman

Rosenberg Calica Birney Liebman & Ross Partner Joshua M. Liebman is an experienced and skilled litigator and transactional attorney.

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Sep 11 • 1:00 AM EDT • Business • libn.com
Greenberg Traurig's Entertainment & Media Practice Congratulates Clients Recognized with CMA Awards Nominations

/PRNewswire/ -- Greenberg Traurig, LLP's Entertainment & Media Practice congratulates its clients on their nominations for the 60th annual Country Music...

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Sep 10 • 8:06 PM EDT • Entertainment • prnewswire.com
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USC awarded $5.6 million from the National Science Foundation

The award would go towards AI optimization on campus.

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Sep 10 • 5:41 PM EDT • Science • uscannenbergmedia.com
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Soy innovation takes center stage at Farm Science Review

By Dusty Sonnenberg, CCA, Field Leader, a project of the Ohio Soybean Council and Soybean Checkoff. The Ohio Soybean Council has a building at Farm Science Review that greets thousands of visitors each year. It is filled with displays that tell the stories of Ohio’s soybean farmers and how their check-off dollars fund research, education,

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Sep 10 • 3:50 PM EDT • Science • wfin.com
Soy innovation takes center stage at Farm Science Review

By Dusty Sonnenberg, CCA, Field Leader, a project of the Ohio Soybean Council and Soybean Checkoff. The Ohio Soybean Council has a building at Farm Science Review that greets thousands of visitors each year. It is filled with displays that tell the stories of Ohio’s soybean farmers and how their

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Sep 10 • 3:30 PM EDT • Science • ocj.com
Goodwin sells part of defence business for £1.1bn to US firm

The group strikes a deal with Cerberus, a firm set up by US defence official Stephen Feinberg.

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Sep 9 • 8:54 AM EDT • Business • bbc.com
Mac Allister 'spoke brilliantly'

Former Chelsea and Everton winger Pat Nevin says Liverpool midfielder Alexis Mac Allister "said exactly the right things" when telling media that he is "very sad" not to have been offered a new deal by the club. The Argentine, who joined on a five-year contract from Brighton in June 2023, saw team-mates Dominik Szoboszlai and Ryan Gravenberch extend their Reds deals this year. "I often hear various players saying things and pushing things a certain way and you get a bit fed up with it," Nevin told BBC Radio 5 Live's Football Daily podcast.

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Sep 9 • 7:56 AM EDT • Sports • sports.yahoo.com
Solomon Islands domestic political squabbles could frustrate diplomatic engagement

No confidence motion withdrawn, but experts say volatility could undermine PM Wale’s pivot to Canberra, Washington

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Sep 8 • 2:31 PM EDT • Politics • rfa.org
Does Medication Abortion Cause An Increase In Mental Health Problems?

A new study published in JAMA Psychiatry looked at medication and procedural abortion and the risk of psychotropic medication use. “We examined whether medication or procedural abortion increased risk of mental health medication use,” study author Julia Steinberg told us. Steinberg is Associate Professor in the Department of Family Science School of Public Health at the University of Maryland. "Based on previous research we have conducted, we did not think medication or procedural abortion would increase risk of mental health medication use.”

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Sep 7 • 8:00 PM EDT • Health • theravive.com
6 Foods High in Antioxidants Besides Cranberries

Cranberries are full of antioxidants—compounds that reduce cell damage and may provide several health benefits—but these foods are also solid sources.

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Sep 7 • 8:00 AM EDT • Health • health.com
30+ Santa Monica businesses master AI at free Grow with Google workshop

Grow with Google hosted a free 'Make AI Work for You' workshop for 30+ Santa Monica small business owners at Annenberg Beach House on Aug. 28, teaching practical AI skills and Google's free tools.

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Sep 7 • 6:00 AM EDT • Business • smdp.com
3 Steps to Support Mental Health for Rural Youth

(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary.Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock googletag.cmd.push(function() { googletag.display('yup-rectangle-one'); });

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Sep 7 • 1:00 AM EDT • Health • leadertelegram.com
3 Steps to Support Mental Health for Rural Youth

(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary.#placement_1042740_0_i{width:100%;max-width:550px;margin:0 auto;}var rnd = window.rnd || Math.floor(Math.random()*10e6);var pid1042740 = window.pid1042740 || rnd;var plc1042740 = window.plc1042740 || 0;var abkw = window.abkw || '';var absrc = 'https://ads.empowerlocal.co/adserve/;ID=181918;size=0x0;setID=1042740;type=js;sw='+screen.width+';sh='+screen.height+';spr='+window.devicePixelRatio+';kw='+abkw+';pid='+pid1042740+';place='+(plc1042740++)+';rnd='+rnd+';click=CLICK_MACRO_PLACEHOLDER';var _absrc = absrc.split("type=js"); absrc = _absrc[0] + 'type=js;referrer=' + encodeURIComponent(document.location.href) + _absrc[1];document.write('');Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock

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Sep 7 • 1:00 AM EDT • Health • berkshireeagle.com
3 Steps to Support Mental Health for Rural Youth

(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary.Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock

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Sep 7 • 1:00 AM EDT • Health • rockymounttelegram.com
3 Steps to Support Mental Health for Rural Youth

(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary.Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock

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Sep 7 • 1:00 AM EDT • Health • reflector.com
3 Steps to Support Mental Health for Rural Youth

(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater. TNCMS.AdManager.render({region: 'fixed-big-ad-top-asset', slot: 1, fold: "above"}); According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary. TNCMS.AdManager.render({region: 'fixed-big-ad-middle-asset', slot: 1, fold: "span"}); Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock TNCMS.AdManager.render({region: 'fixed-big-ad-bottom-asset', slot: 1, fold: "below"});

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Sep 7 • 1:00 AM EDT • Health • news-shield.com
3 Steps to Support Mental Health for Rural Youth

(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.#placement_1126603_0_i{width:100%;max-width:550px;margin:0 auto;}var rnd = window.rnd || Math.floor(Math.random()*10e6);var pid1126603 = window.pid1126603 || rnd;var plc1126603 = window.plc1126603 || 0;var abkw = window.abkw || '';var absrc = 'https://ads.empowerlocal.co/adserve/;ID=181918;size=0x0;setID=1126603;type=js;sw='+screen.width+';sh='+screen.height+';spr='+window.devicePixelRatio+';kw='+abkw+';pid='+pid1126603+';place='+(plc1126603++)+';rnd='+rnd+';click=CLICK_MACRO_PLACEHOLDER';var _absrc = absrc.split("type=js"); absrc = _absrc[0] + 'type=js;referrer=' + encodeURIComponent(document.location.href) + _absrc[1];document.write('');According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary. Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock

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Sep 7 • 1:00 AM EDT • Health • herald-dispatch.com
Weinberg Center continues Families Need Fun ticket program

The Weinberg Center for the Arts will continue its Families Need Fun ticket program for the 2026-27 season, providing complimentary tickets to local families facing significant financial or personal hardship.

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Sep 6 • 9:44 PM EDT • Entertainment • fredericknewspost.com
The science behind the beauty business

Some of Europe’s industrial champions may be in retreat, but its cosmetics sector remains a global leader, buoyed by healthy demand, recognised brands and a reputation for innovation."The fact is, the science in cosmetics is better here in Europe than anywhere else in the world,” says Pierre Morvan, CEO of Technature, a private label cosmetics manufacturer located near Brest in France’s northwestern Brittany region. “You have to have good science in order to make the difference, and that is why we invest so much in research and innovation.”Across Europe, the beauty and skincare products sector supports an estimated 3.6 million jobs, including 265,000 employed directly in the industry, according to the Cosmetics Europe trade group.. Cosmetics production contributes an estimated €11 billion to the EU economy, and generated €30 billion in export revenue last year, a €400 million rise from 2024.Technature itself has a global footprint, supplying products for 1,500 brands in 65 countries. Its range of skin gels, facial masks, nail treatments and other products include natural ingredients and extracts derived from plants, such as seaweed, that are developed and refined through science-based analysis and testing.While industry projections point to sustained growth for the foreseeable future, driven by emerging economies and wider availability of exclusive brands that were once chiefly sold by high street retailers, the sector is not immune to the impact of geopolitics and trade wars. The Trump Administration’s tariff threats have dented cosmetics exports to the EU industry's largest overseas market. After the European Parliament approved the EU-US Turnberry Agreement in June, setting a 15% levy on many EU goods, the French Federation of Beauty Companies warned that “exports are falling sharply” and urged the EU to negotiate an opt-out for cosmetics.Technature’s CEO flags South Korea as an emerging competitor, partly due to its assertive marketing efforts. “I would have to say I am a little bit scared,” Morvan says, regarding the growth potential of the South Korean cosmetics industry. “This is why science and innovation are so important if Europe is to remain the leader.”With a workforce of 200, including biologists, chemists and other scientists, around 15% of Technature’s staff work in three research and development (R&D) labs. A similar number work in four quality control and assurance facilities, where science plays a crucial in ensuring product safety in a sector that is subject to the European Cosmetics Regulation.Educational exchange between industry and academiaIn recognition of Technature’s research and innovation, Morvan was selected as one of Brest’s ambassadors to Science Comes to Town (SCTT), a European initiative to strengthen communications and understanding between science and society. Brest is one of three coastal cities in the EU-funded programme, alongside Split (in Croatia) and Kiel (in Germany). From 7-11 September, Brest will host the EU TalentOn contest featuring 100 early-career researchers from across Europe.Morvan appreciates the value of engagement with educational and scientific institutions as well as the home community. For instance, Technature collaborates closely with university partners to enhance its in-house R&D. In addition, it invites students to its labs and sends its own researchers to local institutions. "We absolutely want the students to know what the industry is all about,” Morvan says, noting that seeing science in action can help young people “understand that they can do something real with science, to create something with what they are learning.” He says another important benefit: encouraging new generations of young people to consider a career in cosmetics.Community involvement also raises awareness about Technature and the skincare industry as a whole. “The public gains recognition of the innovative company that we are, and this is important for getting new customers,” Morvan says. One of its recent innovations — tiny, colourful cosmetic pearls that release skin moisturisers on application — was showcased at this year’s VivaTech event in Paris.Morvan holds a master's degree from the Brest Business School and studied animal production and biology in Brest at the University of Western Brittany (UBO), an SCTT partner, and at the University of Tours. He got his start in business in 2002, initially working on using seaweed as a raw material in the food industry before transitioning to cosmetics. Morvan has always been interested in connecting science and business, reflecting one the goals of SCTT to enhance public-private collaboration.The invitation to participate in SCTT was unexpected. “It was a surprise to get a call from the city of Brest saying that they wanted me on this programme,” Morvan recalls, adding that officials were drawn by his company’s R&D. “It's not only theory and science fundamentals. Our science is something that is applicable to the global market — and important for the community.”Science|Business, which connects policymakers, academics and industry through its news reporting, analysis and events, is an SCTT partner.

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Sep 6 • 8:00 PM EDT • Science • sciencebusiness.net
2. Bundesliga: Kiel end Nürnberg’s perfect start

Goals continue to flow in 2. Bundesliga as Holstein Kiel and Nürnberg were involved in a four-goal thriller. Both teams only led for about five minutes as the four goals were scored in the space of 1...

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Sep 5 • 9:53 AM EDT • Sports • sports.yahoo.com
Amelia Dimoldenberg's 'Chicken Shop Date' is coming to an end

Amelia Dimoldenberg announced on Thursday that her hit show "Chicken Shop Date" is coming to an end.

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Sep 3 • 12:13 PM EDT • Business • businessinsider.com
Spanberger's ICE restrictions dealt major setback as judge warns other blue states

A federal judge blocked a key part of Gov. Abigail Spanberger's law restricting local 287(g) cooperation with ICE as Republicans say they warned her.

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Sep 2 • 3:32 PM EDT • Politics • foxnews.com
20-year-old Haitian student dies; family says loss of TPS led to mental health challenges

Bel was an honors student at Wright State University and was recruited for Wittenberg soccer.

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Sep 1 • 10:44 PM EDT • Health • whio.com
Augusta Health CFO Joe Meador Appointed by Governor Spanberger to Virginia Board of Medical Assistance Services

Gubernatorial appointment places Augusta Health executive on the state board overseeing Medicaid coverage for more than 1.7 million Virginians FISHERSVILLE, VIRGINIA — Augusta Health today announced that Joe Meador, CPA, FACHE, Senior Vice President and Chief Financial Officer, has been appointed by Governor Abigail Spanberger to the Virginia Board of Medical Assistance Services (BMAS), the […]

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Sep 1 • 9:27 AM EDT • Health • augustahealth.com
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Brinkley, Guttenberg revel in retro joy of ‘American Summer’

Sweetly nostalgic as it looks back at one teenager’s “best summer ever,” “American Summer” is also a nod to the friendships and romances that unfold as adulthood beckons.

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Sep 1 • 3:42 AM EDT • Entertainment • bostonherald.com
Ice Island Survives Run-In With Joe Island

In summer 2026, a substantial iceberg calved from Petermann Glacier in northwest Greenland and swiftly drifted into Nares Strait, colliding with an island along the way.

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Sep 1 • 12:00 AM EDT • Science • science.nasa.gov
Public confidence in one's own health care provider remains high

Americans' confidence in their own health care providers remains high, according to a longitudinal, nationally representative survey conducted by the Annenberg Public Policy Center (APPC) of the University ...

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Aug 31 • 10:00 PM EDT • Health • medicalxpress.com
Americans trust their doctors while second-guessing distant intermediaries—now more than ever

The general public is smiling at local healthcare providers while snarling at federal healthcare agencies, according to a survey report posted Aug. 31 by Annenberg Public Policy Center at the University of Pennsylvania.

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Aug 31 • 8:39 PM EDT • Health • healthexec.com
Annenberg poll: Americans trust their doctors when it comes to public health, but not FDA, CDC

Trust in federal government health agencies has dropped in Trump’s second term.

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Aug 31 • 4:27 PM EDT • Health • cidrap.umn.edu
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Public Confidence in One’s Own Healthcare Provider Remains High | The Annenberg Public Policy Center of the University of Pennsylvania

Americans’ confidence in their healthcare providers remains high while confidence in U.S. healthcare institutions has declined since the start of President Trump's second term, an APPC survey conducted from April 2021-August 2026 finds.

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Aug 31 • 8:15 AM EDT • Health • annenbergpublicpolicycenter.org
Virginia Governor: Continued attacks “an effort to get people fearful
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Aug 28 • 12:37 PM EDT • Politics • cnn.com
Scientists May Have Proved a Century-Old Theory That the Vacuum of Space Isn’t Really Empty

Heisenberg said extreme magnetism would make nothingness bend light. A dead star just proved he was right.

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Aug 28 • 10:30 AM EDT • Science • popularmechanics.com
Imaging wait times rise after hospital system purchases private radiology practice

Intermountain Health in January finalized its acquisition of Steinberg Diagnostic Medical Imaging, a 40-year-old radiology group with a dozen locations around Las Vegas.

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Aug 28 • 2:02 AM EDT • Health • radiologybusiness.com
Imaging wait times rise after hospital system purchases private radiology practice

Intermountain Health in January finalized its acquisition of Steinberg Diagnostic Medical Imaging, a 40-year-old radiology group with a dozen locations around Las Vegas.

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Aug 28 • 2:02 AM EDT • Business • radiologybusiness.com
Kiss video at center of Lyons Township FOIA fight could impact Cook County Board, Congress races

Surveillance video showing a kiss between Lyons Township Clerk Elyse Hoffenberg and Bridgeview Mayor Steve Landek has become a political flashpoint in both a Cook County board race and the race for Illinois’ 4th Congressional District.

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Aug 27 • 8:13 PM EDT • Politics • chicagotribune.com
Ottawa taps 64 leading scientists and scholars to bolster Canadian research

The first group of Eddie Goldenberg Research Chairs of Canada includes researchers from 13 countries, with most leaving institutions in the U.S.

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Aug 27 • 6:05 AM EDT • Science • theglobeandmail.com
Virginia governor promises change after accused murderer flees U.S. from mental health facility

Virginia Gov. Spanberger is promising changes after an accused killer fled the U.S. while on unsupervised release from a Fairfax County mental health facility.

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Aug 26 • 8:49 PM EDT • Health • fox5dc.com
Spanberger AG draws fire over two-front fight against Trump enforcement agenda

Virginia Attorney General Jay Jones faces fire over a civil rights probe into Greene County Sheriff Steve Smith's ICE-involved traffic stop operations.

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Aug 26 • 5:49 PM EDT • Politics • foxnews.com
Red Wings GM Search Gets Several Concrete Names

Elliotte Friedman revealed several names connected to the Red Wings GM search, including Brett Peterson, Jeff Kealty and Jeff Greenberg.

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Aug 25 • 10:01 PM EDT • Sports • sports.yahoo.com
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Spanberger: Trump’s trade war with Canada threatens Virginia businesses

Virginia Gov. Abigail Spanberger warned the Trump administration that the escalating trade fight with Canada is hurting Virginia businesses.

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Aug 25 • 12:27 PM EDT • Business • virginiabusiness.com
Entertainment Commentator, Speaker & Analyst Scott Steinberg

Entertainment commentator, on-air analyst, keynote speaker and consultant Scott Steinberg. Pop culture consulting expert: Music movies TV video games books - 3000 brands served!

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Aug 23 • 3:28 PM EDT • Entertainment • futuristsspeakers.com
One New Thing: Supporting Business Professionals in Higher Ed

Jacques Steinberg is a New York Times bestselling author, former New York Times education correspondent and recurring co-host of the “Admissions Beat” podcast. Here is his latest rave on an EdTech resource. The National Association of College and University Business Officers seeks to support and ...

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Aug 20 • 6:28 PM EDT • Business • usnews.com
Australia pushes sporting diplomacy to new levels in the Pacific

Canberra is turning rugby league, military recruitment and Pacific migration into tools of regional influence as it competes with Beijing.

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Aug 20 • 2:46 PM EDT • Sports • politico.com
What Ovaries Reveal About the Secret Ways Women Age, According to Francesca Duncan

“Pretty much every organ system you can think of is touched by the ovaries,” says Francesca Duncan, a reproductive biologist at Northwestern University and Buck Institute for Research on Aging

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Aug 20 • 9:01 AM EDT • Health • time.com
Empowering Health Professions Education in Africa

Through a longstanding collaboration with the University of Global Health Equity in Rwanda, Feinberg medical educators support and train educators who will go on to teach thousands of future physicians, nurses and other health professionals.

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Aug 18 • 10:24 AM EDT • Health • news.feinberg.northwestern.edu
Hayden Panettiere reflected on childhood friendship with Michelle Trachtenberg before her own death

In a 2025 interview with EW, Hayden Panettiere detailed a surprising childhood connection to her ‘Ice Princess’ costar Michelle Trachtenberg: ‘I’m very grateful that I have the memories that I have with her.’

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Aug 18 • 7:00 AM EDT • Entertainment • ew.com
Scientists may have finally proved that “empty” space isn’t really empty

A magnetar’s colossal magnetic field may have revealed a quantum effect predicted by Werner Heisenberg nearly 90 years ago, in which seemingly empty space alters the behavior of light. If confirmed, the discovery could offer the first direct evidence of vacuum birefringence and open a new window into the strange physics of the quantum vacuum.

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Aug 17 • 8:00 PM EDT • Science • sciencedaily.com
After A $42.9 Million Sale, The Shelby Cobra Daytona Coupe Is Now The Most Expensive American Car Ever Sold At Auction

This was the only Daytona personally owned by Carroll Shelby, and it shattered the previous mark of $22 million set by a 1935 Duesenberg SSJ in 2018.

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Aug 17 • 5:55 PM EDT • Technology • jalopnik.com
8 Famous Science-Fiction Writers and Actors Who Served

Before creating some of science fiction’s greatest stories, these 8 writers and actors served in the U.S. military.

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Aug 17 • 3:00 AM EDT • Science • military.com
Internationally Recognized Scientists Expand Miller School of Medicine’s Strength in Disease Modeling and Regenerative Science

New chair Dr. Leor Weinberger is building a team that values fundamental scientific discovery and entrepreneurial energy.

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Aug 15 • 9:45 AM EDT • Science • news.med.miami.edu
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What Should Sharks Expect From Stenberg in Rookie Year?

What should the San Jose Sharks expect from Ivar Stenberg in his rookie season? Two NHL scouts, who watched the […] The post What Should Sharks Expect From Stenberg in Rookie Year? appeared first on San Jose Hockey Now.

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Aug 15 • 3:42 AM EDT • Sports • sports.yahoo.com
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Thomas, Greenberg Tabbed HERO Sports Preseason Group of Six All-Americans

James Madison football standouts Amar Thomas and Zach Greenberg were selected to the 2026 HERO Sports Preseason Group of Six All-American team, as announced ...

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Aug 14 • 10:45 AM EDT • Sports • jmusports.com
Spanberger touts progress keeping insulin, prescriptions affordable during tour of Northern Va. health clinic

Virginia Gov. Abigail Spanberger is touting the progress the state has made in capping insulin costs and keeping prescription drugs affordable.

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Aug 13 • 7:21 PM EDT • Health • wtop.com
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Santa Cruz could lower speed limits near schools, business areas

In 2023, Santa Cruz County ranked worst in the state in reported cyclist deaths and injuries according to the California Office of Traffic Safety. (Nik Altenberg — Santa Cruz Local) 6 p.m. Monday, Aug. 17 Santa Cruz Council Chambers, 809

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Aug 13 • 1:59 PM EDT • Business • santacruzlocal.org
AI needs science’s search history

“Actually, that’s where the gold is,” said Alasdair Russell, my graduate school friend who leads a pre-clinical genome editing group at Cambridge. He was talking about the winding road of science that is omitted from published papers. “When you’re discussing how to do the experiment, and why this way is better than another way, and what does the data really mean? I know what it shows, but what does it mean?” At RAAIS 2026, he described how his group has begun logging the twisting path of discovery as it happens, recording the verbal and written exchanges that normally disappear. Ideas become nodes in a living graph: they branch when a meeting produces two plausible experiments, merge when separate lines of evidence converge, and go dark when someone quietly stops pursuing them. In his implementation, one agent scores novelty, while another tries to learn “how scientists think and how they navigate through a complex world of data,” so that high-potential nodes can trigger deeper investigation. As frontier AI labs deploy agents toward scientific discovery, giving AI authentic scientific taste remains a trillion-dollar dilemma. The bottleneck is that the record we have kept for centuries of science might be insufficient to get us there. The experiments that never make the paper Peter Medawar, 1960 Nobel laureate and “father of transplantation,” asked in 1963 whether the scientific paper was a fraud, and answered yes: the form of the paper misrepresents the thinking that produced it. Sixty years on, the diagnosis is unchanged. A paper presents a clean progression from hypothesis to result to conclusion. Lost along the way are the unconventional theories, the abandoned or unaffordable methods, and the underwhelming and inconclusive data. It reads like a browser history with every dead end deleted: the ten open tabs, the four rephrased queries, the wrong turn down a subforum. All scrubbed, leaving one clean path from question to answer as the canonical path. What has changed since then is that the discarded material is now worth something. No high-impact journal wants these artifacts, but raw trial and error is the most likely source of the training data required to develop scientific intuition, or what researchers call taste. Earlier attempts to capture the discards were motivated by scientific integrity. The Journal of Negative Results in Biomedicine launched in 2002 to publish rigorous studies that disputed established models or exposed ineffective treatments. Its archive preserved negative conclusions after they had become papers, rather than the live alternatives and arguments that produced them. BioMed Central closed it in 2017, saying the mission had been served now that other journals publish null results. A less generous reading is that in fifteen years it published around 200 papers because almost nobody wants to read a negative result, let alone write one up when it will not count toward academic tenure. AI models are different. Even an uninteresting negative result can be useful, provided it is labeled. Earlier this year, Anthropic put a version of this to the test. The company pulled 129 decision points from real Claude Code sessions between January and March 2026, showed models the work up to a human detour, and asked what should happen next. Claude Mythos Preview beat the human choice 64% of the time, while Opus 4.5 managed 51%. The comparison was tilted toward the models because Anthropic deliberately chose moments where the human decision had room for improvement. On 127 further scenarios where the human action was already strong, the models improved on it only about 20% of the time. The study was possible because Anthropic’s researchers work inside a tool that logs by default. The reasoning, detours and outcome are produced in the same working environment. Biology has no equivalent. Its reasoning happens in hallways, at benches, in Slack threads and on whiteboards, while the outcome arrives weeks later somewhere else. The record has to emerge from the work itself. Ask scientists to reconstruct it afterwards and we’ll create another polished account. Subscribe A log is not a label Before any of this becomes training data, a negative result has to say what failed. The first paper published in the Journal of Negative Results in Biomedicine examined 234 negative studies across five leading medical journals. Only 30% discussed statistical power, and half clearly defined a primary outcome. Tell a model an experiment failed, without telling it whether the assay was underpowered, a reagent had degraded, or the hypothesis was simply wrong, and it will learn noise with confidence. Decision histories have a second missing label too. When a lab considers five experiments and runs one, only the chosen branch returns an outcome. The other four are experimental counterfactuals. Researchers call this the selective labels problem: the data reveal results only for the actions someone chose to take. Such a record can teach a model to imitate a lab’s taste, but it cannot establish that the taste was good. It also smuggles local constraints into general lessons. A lab that never ran cryo-EM because it did not own a microscope teaches a model that cryo-EM is rarely the right call. Alasdair’s nodes preserve the candidate set, which is the necessary first step. To be useful, each decision record needs six fields: The evidence available at that moment, and nothing that arrived later. The candidates considered, including the ones dismissed in a sentence. For each candidate: the expected result, the confidence attached to it, and the cost in time and money. The route chosen, and the reason. What happened next. How the evidence changed the scientist’s view. These must be timestamped before the outcome, because hindsight turns uncertainty into inevitability. Disagreement also has to survive. Averaging three scientists into one clean rationale reproduces exactly the information loss we are trying to fix. But there is an obvious failure mode here. Once decisions are logged and scored, people log for the record post-facto. Anyone who has watched an electronic lab notebook fill up with retrospective tidying knows how quickly a research tool becomes a compliance exercise. A record that costs a scientist ten minutes of honest reflection per decision is worth far more than one that costs an hour of performance. A publication initiative called Registered Reports offers a useful starting point. Here, researchers submit their rationale, methods and analysis plan for peer review before the data exist, and the journal commits in principle to publish if they follow the approved plan. Nature has now expanded the format across every field it covers. This approach to paper writing timestamps intent before the outcome, but it freezes one plan. A useful search history must also preserve how the plan changed, which alternatives were rejected, when, and on what evidence. Subscribe Run the runner-up Autonomous labs show what happens when decisions and outcomes are connected in a loop. Liverpool’s mobile robotic chemist ran 688 experiments over eight days in a ten-variable formulation space. A batched Bayesian search used each result to choose the next experiments and found photocatalyst mixtures six times more active than the starting formulations. Every completed experiment changed what the system did next. The robot optimized within a goal and search space that humans had already chosen. It did not decide which scientific question mattered. So what this work demonstrates is narrower, but still useful: a search history pays off when the options return standardized outcomes quickly. Open-ended biology is harder because branches can take weeks and the discarded alternatives may never be run. Some exploration therefore has to be bought. Where two branches are plausible and the stakes justify the cost, a lab should sometimes run the runner-up. Otherwise the record captures what today’s scientists usually chose and stays silent on what they systematically overlooked. A funder could ring-fence a small fraction of a grant for the branch not taken, provided that the decision record and the outcome are both deposited. That costs money, but so does having every lab rediscover the same abandoned path. Test whether taste transfers When it comes time to evaluate if our new AI system exhibits taste, the comparison should run across laboratories and fields. At selected decision points in a live research campaign, we should freeze the six fields: the evidence, the candidates, expected results, confidence, costs and the choice made. Experts then rank the options before the outcomes are known, and those outcomes are checked independently later. We could give models one of two diets - papers alone, or papers plus decision histories - and ask them to rank the next experiment on unfamiliar projects. Then, we score information gained per dollar and week, calibration, and how quickly weak branches are abandoned. If histories improve choices only inside the lab that produced them, they amount to useful organizational memory. If they improve choices on unfamiliar problems elsewhere, Alasdair’s group will have captured something science has never managed to write down: a transferable record of taste. Until that happens, a scientific search history is a promising record, not yet a training set.

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Aug 13 • 11:16 AM EDT • Science • press.airstreet.com
Immortality creator Sam Barlow's new video-scouring game is sci-fi horror Precognition, a collab with filmmaker Brandon Cronenberg, in which you see and change the future

Her Story and Immortality creator Sam Barlow is back with a new video-scouring game, and this time it's a sci-fi horror.

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Aug 12 • 3:30 PM EDT • Technology • eurogamer.net
Precognition, A New Horror From Sam Barlow And Brandon Cronenberg, Is Confirmed For Switch 2

"We’ve pushed ourselves even harder"

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Aug 12 • 3:30 PM EDT • Technology • nintendolife.com
Dem governor booed at Virginia Old Fiddlers' Convention

Video shows Virginia Democratic Gov. Abigail Spanberger greeted by loud boos at the Old Fiddlers' Convention in Galax amid sagging poll numbers.

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Aug 11 • 11:58 AM EDT • Politics • foxnews.com
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice

AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.

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Aug 10 • 8:24 AM EDT • Health • fiercebiotech.com
Seedless and WatermelonDS Drop Their Latest Updates at Once

The world of Nintendo DS emulation has always been a bit of a strange thing. You're either in the camp where the emulation is fine, or the one where it's just better to do it on an original console. Recently though, those lines have been blurred with dual screen releases like the Anbernic RG DS,

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Aug 8 • 3:06 PM EDT • Technology • retrohandhelds.gg