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Nintendo joins Best Buy for midnight Zelda 40th Anniversary Switch 2 restock launch
📅 The Zelda 40th Anniversary Switch 2 releases on Thursday, October 27 🚨 Our Zelda Switch 2 restock tracker @mattswider on X will send out an alert when stock appears 😲 Nintendo Store held a surprise restock on October 26 and is holding a midnight launch event on November 5 🙏 Other retailers may be holding back stock for launch day, too Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Target: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 🚨 Want the Zelda 40th Anniversary Switch 2? Drop your email for restock alerts before it sells out. ⤵️ Subscribe We’re expecting to see a Zelda 40th anniversary Switch 2 restock tomorrow at major retailers like Walmart, as the console and Pro Controller are set to launch. However, Nintendo has joined Best Buy in announcing a midnight launch event for The Legend of Zelda: Ocarina of Time on November 5, where limited quantities of the special edition console will be available. There is a catch, though. To attend the in-store event, which will be held on November 4 at Nintendo San Francisco and November 5 at Nintendo New York, a Warp Pipe Pass is required, which means capacity will be limited. If you’re lucky enough to receive a Warp Pipe Pass (they’re currently fully booked), you’ll be able to purchase The Legend of Zelda 40th Anniversary Edition console, Zelda 40th Anniversary Nintendo Switch 2 Pro Controller and display stand, the Zelda 40th Anniversary Switch 2 Pro Controller on its own, and the Zelda 40th Anniversary carrying case and screen protector. Purchases will be limited to one “per customer” and will be sold on a “first come, first served basis.” Why you should follow our Zelda Switch 2 restock tracker Obviously, many will be looking to receive the Zelda Switch 2 before November 5, and an instore event isn’t exactly ideal for many. That’s where our exclusive Zelda Switch 2 restock tracker comes in, as we’re providing up-to-the-second US store inventory checks. Those who follow Matt Swider on X and turn on notifications will be the first to know when new stock is live, as you can see in the post below. [ Matt Swider (The Shortcut)@mattswider ](https://x.com/mattswider/status/2114758291322757239?s=20) Zelda Switch 2 console in stock at the Nintendo Store nintendo.com/us/store/produ… 4:37 PM · Oct 26, 2026 · 67K Views 18 Replies · 4 Reposts · 75 Likes We’re strongly expecting retailers like Walmart to have stock on launch day, especially as it’s the largest retailer in the US. Cancellations can also occur in the run up to release, meaning more stock is made available that was previously taken. Thursday and Friday mornings is also when Walmart tends to offer restocks online. We’re predicting other retailers like Target, GameStop and Amazon will also get a new wave of consoles on launch day, and we’ll notify you if and when any Zelda Switch 2 restocks appear. You can trust our restock tracker as we helped over 400,000 people buy Sony’s console when it was in and out of stock for two years. We’ve since made it our goal to help our subscribers purchase hard-to-find items. We’ve done the same with the PS5 30th anniversary edition and many more in-demand products. Up next: Zelda 40th Anniversary Switch 2 Pro Controller restock looks increasingly likely at Nintendo Store Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.
MIT affiliates named 2026 Schmidt Sciences AI2050 Fellows
MIT faculty members Sendhil Mullainathan, Alex Damian, Bailey Flanigan, Yunha Hwang, and Manish Raghavan, as well as two additional alumni, were recently named to the 2026 cohort of Schmidt Sciences AI2050 Fellows.
Kyle Whittingham sends a strong message about Michigan's coaching staff
Kyle Whittingham expresses the need to stay calm amid a tough season for the Wolverines.
Zelda 40th Anniversary Switch 2 restock update: the Nintendo Store remains your best bet
🎮 The Zelda 40th anniversary Switch 2 was released on October 29 and flashed in and out of stock at the Nintendo Store 🚨 Our Zelda Switch 2 restock tracker @mattswider on X will send out an alert as soon as stock appears 👀 Walmart was our top pick to have a restock, but a supply chain delay has pushed the date back ⌚ In-store midnight launches are being held at GameStop, Best Buy, and Nintendo New York/San Francisco Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 The Legend of Zelda 40th Anniversary Switch 2 launched yesterday, and it was the Nintendo Store that held the most restocks. The console flashed in and out of stock repeatedly throughout the day as limited units were sold and quickly snapped up. 🚨 Want the Zelda 40th Anniversary Switch 2? Drop your email for restock alerts before it sells out. ⤵️ Subscribe Many were met with error messages, “sold out” signs, or “couldn’t add the required amount” to their baskets. However, with a little persistence and luck, others were more successful. As it stands, it’s the best place to try to get the Zelda Switch 2, even if the experience can be a little frustrating. We’re expecting a similar situation today as our tracker continues to receive restock alerts. However, we’re reluctant to share them all as many have been false flags, but we immediately notified The Shortcut followers once the first restock went live. [ The Shortcut@theshortcut Zelda Switch 2 is back in stock at the Nintendo Store: nintendo.com Nintendo Switch™ 2 – The Legend of Zelda™ – 40th Anniversary Edition - Nintendo Official Site 4:18 PM · Oct 29, 2026 · 2.09K Views 2 Replies · 2 Likes ](https://x.com/theshortcut/status/2115840807773299128?a=b6yhtCFmoswv5lWWvEs&s=20) Amazon was the only other retailer to hold an online restock, though it sold out almost instantly. No more restocks took place, and sadly, the major Walmart restock of the Zelda Switch 2, which we were confident would take place, did not happen because of a supply chain issue. [ Matt Swider (The Shortcut)@mattswider ](https://x.com/mattswider/status/2115824408938111299?a=quc3qYd6I_Qe5wag2lU&s=20) 🚨 Zelda Switch 2 console at Amazon right now amazon.com/dp/B0HJ6F8L6V?… amazon.com Nintendo Switch™ 2 –The Legend of Zelda™ – 40th Anniversary Edition 3:13 PM · Oct 29, 2026 · 76.7K Views 32 Replies · 4 Reposts · 57 Likes The console will now be available to order online at Walmart on November 6, with Target also offering the same date. Some lucky shoppers could also get the Zelda Switch 2 in-store, with The Shortcut readers sharing their personal accounts of getting the console at Walmart and helping each other out. If you’re willing to travel to your local store, Best Buy and Nintendo are holding in-store events on November 5 (though you’ll need a Warp Pipe Pass for Nintendo’s event). GameStop is also letting customers pre-order in-store.. We’ll still be tracking every retailer with our exclusive Zelda 40th anniversary Switch 2 restock tracker, which provides up-to-the-second information when the Zelda Switch 2 is in stock. If the console appears – which it might – our followers will still be the first to know. Up next: PS5 Pro restock: it’s available again, but you’re paying more than you should Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.
Linfield knock Coleraine off top spot with statement win
Linfield leapfrog Coleraine at the top of the Irish Premiership and send out a statement of intent with a comprehensive 3-0 win over their rivals at Windsor Park.
Election '26: Local officials discuss early voting, federal monitors
The Department of Justice is gearing up to send 1,000 election monitors to sites around the country on Election Day. Champaign County is expected to be among them, said County
General Dynamics tops quarterly estimates on robust Gulfstream, marine bookings
Oct 30 (Reuters) - General Dynamics on Friday beat Wall Street expectations for third-quarter profit and revenue on strong bookings in its Gulfstream business jet and shipbuilding units, sending the defense contractor's shares up about 4% before the bell.
James Talarico Wants to Send the Dallas Mavericks Packing: Is Oklahoma City Ready for Another Texas Team?
DALLAS, Texas — Dallas Mavericks fans have survived rebuilding seasons, heartbreaking playoff exits and enough roster drama to fill an entire season of television. But now comes an even bigger nightmare: the possibility of losing the Mavericks altogether. In this satirical look at Texas politics, James Talarico’s controversial sports positions inspire a question Dallas fans…
Capitals Trade For Devils’ 25-Year-Old Goalie
The Washington Capitals have traded for a goalie. The news was announced officially Sunday morning that the Caps completed a trade with the New Jersey Devils for Remi Poirier. The Capitals are sending the Devils a fourth-round draft pick in return. #NEWS: We’ve acquired a 2027 seventh-round pick from the Washington Capitals for goaltender Remi […] The post Capitals Trade For Devils’ 25-Year-Old Goalie appeared first on HEAVY.
Blue Jays decline Myles Straw’s 2027 option
The Toronto Blue Jays declined their 2027 club option on outfielder Myles Straw on Monday, sending the veteran into free agency after two seasons with the team. The option would have paid Straw $8 million next season. Instead, he receives a $1.75 million buyout, which the Cleveland Guardians cover under the terms of the trade that brought him to […] The post Blue Jays decline Myles Straw’s 2027 option appeared first on ClutchPoints.
Flooding sends water into Arts District small business shops
Business owners and neighbors worked to keep shops open near Commerce and Imperial
Vettel sends emotional message to new youngest F1 champion Antonelli
Four-time Formula One world champion Sebastian Vettel sent an emotional message to Kimi Antonelli after the Italian became the sports' youngest-ever champion at 20 years old on Sunday. The German, now retired, was the previous youngest F1 champion.
Matt LaFleur Sends Strong Message to Packers Breakout Candidate
The Green Bay Packers are likely to be without wide receiver Matthew Golden in their Week 8 matchup with the Carolina Panthers. This is going to leave a massive opportunity for second-year wide receiver Savion Williams. Head coach Matt LaFleur noted that Williams has already given the team a spark on offense, but he expects […] The post Matt LaFleur Sends Strong Message to Packers Breakout Candidate appeared first on HEAVY.
Iowa politics: Meet the candidates for Iowa's 3rd Congressional District
Will Iowa voters reelect Zach Nunn for a third term, or send Sarah Trone Garriott to Washington? Here’s how the candidates compare.
Flooding sends water into Arts District small business shops
Business owners and neighbors worked to keep shops open near Commerce and Imperial
Elvis has entered the courtroom
The owners of Elvis Presley’s music are suing Anthropic, alleging it helped itself to the King’s songs to train its AI — and sending a $41 million reminder, according to the New York Times.
Despite concerns, the Trump administration still sends pregnant migrant minors to south Texas
Several children have had to leave the state to receive medical care, including abortions, that is unavailable in Texas.
LeBron James' lawyers send cease and desist to AI sports-betting app that used his name and likeness
Brandy Lefsyk to blend science and holistic wellness in November
TOWNSEND — Imagine settling into a quiet room, letting the stresses of the day fall away as soothing sounds and gentle vibrations create space for stillness and reflection.
Steelers Guard Mason McCormick Sends Message to Jared Verse
Pittsburgh Steelers left guard Mason McCormick was called for a personal foul on Jared Verse on an extra point after […]
Shine Bright for Voyager’s Light‑Day
Use our Automated “V-G-R” Flasher to send your signal to Voyager, or if you want to try Morse code yourself, see our “Shine Bright” Step-by-Step instructions
Giovanni Carnevali sends stern message to underperforming Juventus squad
Luciano Spalletti has ordered Juventus players to attend a training retreat as the club attempts to address their disappointing run of form. Sporting director Giovanni Carnevali has also delivered a s...
Still searching for a Zelda 40th Anniversary Switch 2? Nintendo has good news
🥳 Nintendo confirmed Zelda 40th anniversary celebrations will continue into next year, suggesting ongoing Switch 2 restocks 🚨 Want the Zelda Switch 2? Follow our Zelda Switch 2 restock tracker @mattswider on X and we’ll send out an alert when stock appears 🙏 Unlike other limited editions, the console is not expected to have a restricted production run 💰 The special edition costs $519.99 for its ornate design, but does not include the Ocarina of Time remake 🙌 Nintendo President Shuntaro Furukawa ruled out future console price increases due to secured memory supply Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 Restock Dashboard: Get our live, audible siren alerts The Legend of Zelda 40th Anniversary Switch 2 is hard to find right now, though we’re doing our best to help people get one using our exclusive restock tracker. However, there is some good news to share. 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 Subscribe Nintendo has provided an update that suggests the console will be easier to obtain in the future. Speaking during Nintendo’s financial results, president Shuntaro Furukawa said that The Legend of Zelda’s 40th anniversary celebrations will continue into next year (thanks, Stealth40k). That strongly suggests that the Zelda Switch 2 console will continue to be restocked, and that it won’t be constrained by a limited production run. Unlike the Xbox Series X25 limited edition – where only 25,000 units have been produced – the Zelda 40th anniversary Switch 2 should be more obtainable once the initial demand from buyers dies down. Of course, whether you can wait as long as next year to get hold of the Zelda Switch 2 is one thing, but knowing that the console will eventually become more widely available should please those who are worried about missing out. The Legend of Zelda 40th anniversary special edition Switch 2 costs $519.99, but doesn’t include a copy of The Legend of Zelda: Ocarina of Time remake. You’re basically paying a $20 premium over the standard Switch 2 for the beautiful ornate design. Luckily, it sounds like the price of the Switch 2 will remain at $499.99 for the foreseeable. Furukawa ruled out any future price increases as Nintendo has managed to secure sufficient quantities of memory. That also means the price of the Zelda Switch 2 won’t be affected. Up next: Zelda 40th anniversary Switch 2 restock: here’s when Target should have stock Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.
With death sentence clemency, Newsom takes another big political risk
Amid speculation about how the mass commutation could help or hurt his presidential prospects in 2028, Gov. Gavin Newsom's decision pushes the boundaries of his authority and sends a clear message to the nation about where he stands.
Zelda 40th Anniversary Nintendo Switch 2 restock signals good news for launch day buyers
📅 The Zelda 40th Anniversary Switch 2 releases on Thursday, October 27 🚨 Our Zelda Switch 2 restock tracker @mattswider on X will send out an alert when stock appears 😲 Nintendo Store held a surprise restock yesterday, which is good news for other retailers 🙏 It suggests other retailers may be holding back launch day stock, too Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Target: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 🚨 Want the Zelda 40th Anniversary Switch 2? Drop your email for restock alerts before it sells out. ⤵️ Subscribe We predicted that a Legend of Zelda 40th Anniversary Switch 2 restock would happen on launch day, October 29, and we’re now even more confident after the Nintendo Store’s surprise restock yesterday. Our followers were the first to know that the Zelda Switch 2 was back in stock at the Nintendo Store, and the console even promised to arrive on launch day if you managed to secure one. [ Matt Swider (The Shortcut)@mattswider ](https://x.com/mattswider/status/2114758291322757239?s=20) Zelda Switch 2 console in stock at the Nintendo Store nintendo.com/us/store/produ… 4:37 PM · Oct 26, 2026 · 67K Views 18 Replies · 4 Reposts · 75 Likes It strongly suggests that other retailers such as Walmart, Target, GameStop, Amazon and Best Buy will have more units – albeit in limited quantities – on launch day for those who currently don’t have a pre-order. Retailers often hold back stock for launch day buyers who haven’t pre-ordered. Cancellations can also occur in the run up to release, meaning more stock is made available that was previously snapped up. Zelda Switch 2 restock – why Walmart will have stock Walmart historically holds back extra stock for launch day, and we’re expecting the same to happen on October 29. As the largest retailer in the US, it usually has the biggest stock allocation, and Thursday and Friday mornings is when the retailer tends to offer restocks online. As we mentioned previously, Nintendo was also a retailer to watch – and it went live with a restock earlier than we thought. It had previously promised the Zelda 40th anniversary Switch 2 would be “replenished”, and it offered a limited amount of stock for those who were lucky enough to snag one. (Hint: Followers of Matt Swider on X and our restock tracker were first in line.) We’re expecting other retailers like Target, GameStop and Amazon to get a new wave consoles on launch day, and we’ll notify you if and when any Zelda Switch 2 restocks appear. Why you should follow our Zelda Switch 2 restock tracker Remember when you couldn’t find a PS5 for nearly two years? Not our followers. We helped over 400,000 people buy Sony’s console when it was in and out of stock, and we’ve since made it our goal to help our subscribers bag hard-to-find times. We’ve done the same with the PS5 30th anniversary edition, Nintendo Switch 2, and many more in-demand products. With up-to-the-second US store inventory checks, The Shortcut and Matt Swider on X offers exclusive Zelda 40th anniversary Switch restock updates. You’ll also receive an instant notification on X (if set to on) as soon as new stock arrives. Up next: Zelda 40th Anniversary Switch 2 Pro Controller restock looks increasingly likely at Nintendo Store Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.
Chiefs Trade Worthy For Jaguars’ Thomas In Bold Swap
A proposed trade sends Xavier Worthy to Jacksonville for Brian Thomas Jr. Heavy.com breaks down the numbers and the logic behind the move.
Nashville Predators trade Matthew Wood to Seattle Kraken for Shane Wright
The Nashville Predators made a trade on Nov. 1, sending center Matthew Wood to the Seattle Kraken for center Shane Wright.
Tampa Police upping patrols in entertainment districts ahead of Halloweekend
The Tampa Police Department will be sending more resources to high-traffic areas and entertainment districts to prevent drunk driving and “reckless behavior” this Halloween weekend.
Send your name to Saturn's largest moon
NASA's mission to search for life’s building blocks on Titan is scheduled for 2028.
Madueke admits he was nervous during Liverpool VAR review
Arsenal’s Noni Madueke has admitted he was worried about VAR intervening to send him off during Sunday’s game against Liverpool, despite not feeling he’d done anything wrong.Photo by Michael Ste...
Scientists find a way to send smells online
Researchers have developed a system that can detect an odor, transmit information about it over the internet, and release a corresponding scent through a wearable device, Qazinform News Agency correspondent reports, citing a study published in Science Advances.
Todd McLellan Sends Blunt Message Following Dylan Larkin Drama
Todd McLellan delivers a blunt message about Dylan Larkin following the Red Wings' 4-1 victory over Chicago and Larkin's suspension without pay.
“Big Brother” winner Rick Devens’ wife announces breast cancer diagnosis: ‘Send good vibes and prayers’
“Rick won ‘Big Brother’ and then we came home and I got diagnosed with breast cancer.”
New Android SMS of Death exploit can remotely crash unpatched phones
A security researcher has released a proof-of-concept exploit for a recently patched Android vulnerability, dubbed "SMS of Death" and tracked as CVE-2026-58882, that lets attackers remotely disrupt cellular service or crash phones by sending a specially crafted text message.
Flooding sends water into Arts District small business shops
Business owners and neighbors worked to keep shops open near Commerce and Imperial
Joe Mazzulla Sends Strong Message About Paul George
Joe Mazzulla made it clear just how important Paul George has become to the Celtics.
Smashing science: Pumpkins plunge 70 feet in Boston University Halloween tradition
Boston University students got a crash course in physics by sending more than 30 pumpkins plunging onto Metcalf Plaza.
“Happy Days” Star Henry Winkler Reveals the ‘Unbelievable’ Birthday Gift That ‘Thoughtful’ Ron Howard Sends Him Every Year
Winkler, 81, and Howard, 72, have been friends for over 50 years
Philly sports team owners are sending big checks to Josh Shapiro. But he’s not the only one.
An Inquirer analysis of campaign finance data explored how owners of Philly sports team are spending on politics. Josh Shapiro is one of the big winners.
USA TODAY Sports mock draft sends Florida's Jadan Baugh to Browns
USA TODAY Sports' latest NFL mock draft projects Florida running back Jadan Baugh to the Cleveland Browns in the first round.
Lions’ Rival Could Face Punishment From NFL After Officiating Comments
The Detroit Lions did what they had to do against the divisional rival Green Bay Packers, defeating them by a 24-21 final score thanks to a last-second field goal from placekicker Jake Bates, sending the sold out crowd of Detroit fans at Ford Field into a frenzy.With the victory, the Lions improved their record to […] The post Lions’ Rival Could Face Punishment From NFL After Officiating Comments appeared first on HEAVY.
New health center opens at Port Townsend school
Leaders celebrate opening at the Blue Heron/OCEAN K-12 campus
With death sentence clemency, Newsom takes another big political risk
Amid speculation about how the mass commutation could help or hurt his presidential prospects in 2028, Gov. Gavin Newsom's decision pushes the boundaries of his authority and sends a clear message to ...
Bruins' Pavel Zacha Sends Strong Message In Win Over Penguins
Pavel Zacha scored twice against Pittsburgh, but his performance revealed something even more encouraging about the Bruins' increasingly dangerous offense.
Empower Your Most Curious Employees to Drive Your Digital Transformation
Leaders seeking to turn AI’s promise into business value often overlook employees already experimenting with emerging technologies. These “digital wayfinders”—frequently younger, junior employees but defined by their exploratory approach rather than their age—can reveal new possibilities, challenge established assumptions, and accelerate digital transformation. Indeed, research involving almost 10,000 leaders across 108 countries suggests that organizations making greater progress are more likely to engage these employees. But these employees’ tendency to experiment without permission and challenge established thinking candidly can also send promising initiatives off track and alienate leaders. To channel their contributions productively, leaders should build candid, two-way communication; remove unnecessary bureaucracy while establishing clear business and ethical guardrails; and provide “air cover” through visible sponsorship and support and opportunities to influence consequential decisions.
Packers Send Fans Into Panic After News About Franchise Legend
Former Green Bay Packers head coach Mike Holmgren could soon be getting his gold jacket. It was recently announced that Holmgren is among those being considered to be enshrined into the Pro Football Hall of Fame again. “Former head coach Mike Holmgren, who led the Packers to back-to-back Super Bowl appearances in the 1996-97 seasons, […] The post Packers Send Fans Into Panic After News About Franchise Legend appeared first on Gridiron Heroics.
Report: Seahawks Land Quenton Nelson Ahead of Trade Deadline
The Colts are reportedly sending eight-time Pro Bowler Quenton Nelson to Seattle, and the price was small. #NFL
Science Begins With Wonder and Sometimes With a Salamander.
The Bar Harbor Story is generously sponsored by the Don & Beth Straus Center at Birch Bay Village. BAR HARBOR—The children had come to see the axolotls, those odd little salamanders with pink frills around their heads and the remarkable ability to grow back what they lose. But also there were stickers. There were crafts. There was the kind of excitement that makes a roomful of kindergarteners forget, for a little while, that sitting still is ever a requirement. And then there were the animals themselves, alive in their clear cases at the MDI Biological Laboratory, where 12 children from Pemetic Elementary School got to meet the creatures they had been learning about in class. “Do you love them?” their teacher, Carol Null, asked. The answer came back in a chorus. “I do!” “I do!” “I do too,” Null said, smiling. “I love them even more now.” That was the thing about a day at the lab. Science was no longer a picture in a book, or a word on a classroom wall. It had a face, a tail, and a set of extraordinary powers. And for a child, sometimes that is where wonder begins. Sometimes learning about science is about stickers. Sometimes it’s about bright pink feathers and getting super excited about that glow in the dark. Sometimes learning about science is joy—pure and simple joy. That’s how it was October 28 at the MDI Bio Lab as Miss Hannah (known in the lab as Dr. Hannah Lust, director of STEM, undergraduate and graduate Training), other scientists, graduate students, and MDI Bio Lab staff, hosted 12 students from Carol Null’s Pemetic Elementary School’s kindergarten class. The 2.5-hour program created by Dr. Lust focused on axolotls, a species of mole salamanders, a superhero in the animal world: a superhero with some scientific-study worthy superpowers. One of those superpowers come from the axolotls’ ability to regenerate body parts, including entire limbs. But also, they’re cute. This fall, before coming to the internationally renowned lab nestled in Salsbury Cove, Null has been integrating axolotls into her class. They’ve been part of the kids’ vocabulary and their storytelling. They’ve been part of science. They’ve been part of the children’s learning about facts vs opinions. The Pemetic Elementary kindergarten students learn about invasive species and the impact on the ecology and one student related it to their dad, who lobsters, and his worries about green craps, an invasive species in Maine. “Are they bigger or smaller than you thought they’d be?” the children are asked after the scientists show them multiple see-through cases of axolotls, lined up on a table that they’re told not to jiggle. “Bigger!” “I think they’re bigger.” “Smaller!” The bio lab opening its doors to the collaborations and to students and families is a norm, but this is the first program of this kind. It’s meant to encourage kindergarten students about axolotls. But when the students come to the bio lab something else happens too—something beyond Null’s child-focused teaching—the students see science—and the regenerating creatures in real life. They do crafts. They speak with them. They meet people who know all about them: scientists and educators who talk to the kids like they’re equals. That’s a superhero power, too. Null speaks about meeting the kids where they’re at in her classroom, letting their interest and hearts lead her in their learning. That requires recognition of interests, of individuality, of empathy. Some would argue that’s a super power, too, but it’s also in those 12 students as they listen to the storybook, encounter those live axolotls, and hear about how axolotls might help advance society’s understanding of human health. As Eddie Seckeler (comparative animal models, CORE facility manager), carefully puts the axolotls on a cart and rolls them away, some of the children stop what they’re doing to watch. “Bye axolotls.” “Bye!” “Bye!” The axolotls are not just images in a book, Hello, I’m an axolotl by Hayley and John Rocco; they are real and cool. MDI Biological Laboratory scientists Dr. Prayag Murawala and Dr. James Godwin who both feature in the Roccos’ book. The kindergarteners get to meet them in real life, off the page, in the world, doing science. They learn from them, laugh with them. “The visit is about more than meeting an unusual animal. By introducing children to scientists working in their own community, the experience helps make science tangible and accessible. Students can see that science is not just something they read about in books or learn about at school. It is something real people do every day by asking questions, making observations and working to understand how the world works,” explains MDI Biological Laboratory Director of Communications Rebecca Woods. While the students make axolotl-related crafts around tables, graduate students and staff help out. Ryan holds up his construction paper setting and axolotl to show Omar Maged, a graduate student. “Do you like it?” Ryan asks, eyes wide, turning from his axolotl to look up at Omar. Omar studies the construction paper for a moment, smiles and says definitively, each word important. “It is beautiful.” Null says that she’s so thankful for all the “amazing” community partners that her school and her students get to interact with as they learn and grow and live, but emphasized how the MDI Bio Lab goes out of its way to create something meaningful, something that allows her young students to build their own agency, to know that they can be impactful in their community, to show them how how things they learn about in text is connected to themselves and their community. Woods explains, “Axolotls have an extraordinary ability to regenerate, or regrow, certain body parts, including limbs. Scientists study these animals to understand how regeneration works and what their biology might teach us about tissue repair and healing in humans.” The children enter the space for “a memorable introduction to a big scientific question,” Woods said. “How can some animals regrow body parts? The encounter encourages children to look closely, wonder about what they see and begin to understand how scientists use observations and experiments to investigate questions.” “For the students, the visit is an opportunity to explore a fascinating animal and meet scientists in their own community,” Woods explains. “For MDI Biological Laboratory, it is a chance to share the excitement of research, nurture curiosity, and help young learners discover that science begins with asking questions.“ At the beginning of the school year, Pemetic kindergarteners didn’t know what the axolotl was—at least not exactly—now they know all about the axolotl’s life cycle. “It’s different than a butterfly,” one student told Mrs. Null. It is. The change and knowledge might seem small**,** but it offers a glimpse of what happens when a subject moves beyond the pages of a book and into a child’s world. The children have been learning about butterflies at the Charlotte Rhoades Park and Butterfly Garden. At both the garden and the MDI Bio Lab, the children see the animals, meet the scientists who study them and at the lab encounter a question that researchers are still working to answer: how can some creatures regenerate body parts, and what might that teach us about healing in humans? They leave with gift bags, paper-plate salamanders, new things to wonder about and a connection between the science they learn in school and the work happening in their own community. The axolotls may be remarkable for their ability to grow back what they have lost. For these young students, the day offers something different: a chance to discover how much there is to ask, observe, and imagine. When Null’s students had time to use chalk and draw whatever they want, in the beginning of the year, they drew rainbows. Now? They’re using that chalk and choosing to draw axolotls instead. About MDI Bio Laboratory For more than 125 years, MDI Bio Lab has been a center for training and research in comparative biology. In the last two decades its biomedical research has focused on aging, regeneration, and environmental toxins. The Laboratory houses 11 research groups staffed by an international team of world-class scientists and graduate students. It also leads a statewide network of colleges, universities and research institutions that collaborate to provide training, research experiences and financial support to help young Mainers play a bigger role in today’s biomedical revolution. Located on Maine’s rugged coast, the Laboratory’s 100+ acre campus houses research facilities, cottages and dorms that house visiting scientists and students. It is also home to MDI Bioscience, a subsidiary working to design innovative techniques to speed the drug discovery process. The Bar Harbor Story is generously sponsored by Rick Osann Art. LINKS TO LEARN MORE NIH INBRE MDI BIOLOGICAL LABORATORY Pemetic Elementary School Hello, I’m an Axolotl Photos: Carrie Jones/Bar Harbor Story HELP SUPPORT THE BAR HARBOR STORY When we started The Bar Harbor Story, we didn’t know if anyone would read it. But you showed up. You shared. You sent tips. Now—over 400,000 views every month later—it’s clear: people here care about their community and each other. We’ve kept everything free because news should never be out of reach, but every one of our stories takes time to write, and your support keeps The Bar Harbor Story going. If you value our work, please consider a paid subscription, a founding membership, or a sponsorship. It truly helps us cover one more meeting, tell one more story, shine one more light. Even $5 a month makes a difference. Click here to become a one-time supporter now. Thank you so much for being here. Founding member information can be found here. Have questions about sponsorships? Just send Shaun an email at sfarrar86@gmail.com, he’d love to hear from you. Subscribe Share Bar Harbor Story Share Leave a comment
A single sauna session sends immune cells surging through your body
A new Finnish study reveals that just 30 minutes in a sauna can temporarily flood the bloodstream with additional white blood cells, potentially helping the immune system patrol the body and detect threats. The surprising response resembles the immune boost seen during exercise and may help explain some of the health benefits linked to sauna bathing.
Man charged with mailing hundreds of letters containing powder to officials ahead of the election
Federal authorities charged an Oklahoma City man with sending hundreds of letters containing white powder and ominous warnings about treason to public officials ahead of the 2024 and 2026 elections.
The German Makkabi sports club where Muslims outnumber Jews
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Flooding sends water into Arts District small business shops
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Waymo for Business now files robotaxi receipts to Ramp automatically
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How Huntsville Small Businesses Can Partner With NASA To Land Humans On The Moon In 2028
In 2027, NASA plans to send four astronauts aboard its Orion spacecraft on a 14-day mission in low Earth orbit to test systems needed to return humans to the
Bears Send Breakout Starter to IR After Jeffery Simmons’ Debut
The Chicago Bears welcomed the NFL's best defensive tackle in Jeffery Simmons, then lost a regular starter the next game. The post Bears Send Breakout Starter to IR After Jeffery Simmons’ Debut appeared first on HEAVY.
UDE students develop wearable sensor patch for noninvasive health tracking
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'MP3' stars Paul F. Tompkins, Skye Townsend, and Aparna Nancherla on improv, 'TRL,' and 'kisses'
Dropout's new scripted series pulled some influence from "Curb Your Enthusiasm," and Nancherla's closet.
5 things to do this week in Greenville
See our curated list of upcoming and ongoing arts, culture and entertainment events in the Greenville area. Send us your events at greenville@postandcourier.com.
‘The tone is different": Minnesota AG reacts to DOJ sending election monitors to all 50 states
Burgas beckons: Head to Bulgaria next year for Eurovision 2027
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Flooding sends water into Arts District small business shops
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After Cancelling Zelda Switch 2 Pre-Orders, Walmart Is Now Supposedly Sending Out $519 Gift Cards
Some customers also claim they've been able to "reorder" the system
More charged with voting as noncitizens in NC + DOJ to send election monitors
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Browns Coach Sends Strong Message About Shedeur Sanders
The Cleveland Browns are set to get their first look at Shedeur Sanders in his second season on Sunday afternoon against the New Orleans Saints on the road. Deshaun Watson is set to miss this week’s game due to a concussion. That has given Sanders a chance to get on the field and show what […] The post Browns Coach Sends Strong Message About Shedeur Sanders appeared first on Gridiron Heroics.
Milwaukee Brewers’ Jackson Chourio Sends Strong Message Amid World Series
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Flooding sends water into Arts District small business shops
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‘Lot of Us Concerned About You,’ ‘Sending You Love’ — NFL World Reacts As ESPN Reporter Announces She’s Stepping Away Due to Health Issues
Jenna Laine has been a familiar face on the Tampa Bay Buccaneers beat for years, so her absence from the press room did not go unnoticed. The ESPN reporter has now explained that she needs time away to deal with medical issues, though she has not said when she will return.
Bologna ponder sending Dovbyk back to Roma in January
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Television Q&A: Why do dogs get barking mad at 'The Traitors...
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Zelda 40th Anniversary Switch 2 restock: Walmart and Target confirm exact release dates
🎮 The Zelda 40th anniversary Switch 2 is out today, October 29, but Walmart and Target are planning online restocks for November 6 🚨 Our Zelda Switch 2 restock tracker @mattswider on X will send out an alert as soon as stock appears 👀 Walmart was our top pick to have a restock, but a supply chain delay has pushed the date back ⌚ GameStop, Best Buy, and Nintendo are holding in-store midnight launches where units will be available Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Target: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 A new update has dashed our hopes of a major Walmart restock of the Zelda Switch 2 console, which we were confident would happen today. However, a new Reddit post (thanks, Wario64) has revealed that Walmart is waiting until at least November 6 to sell the special edition console online. 🚨 Want the Zelda 40th Anniversary Switch 2? Drop your email for restock alerts before it sells out. ⤵️ Subscribe A employee note says: “Due to a supply chain delay, some stores may not receive the Nintendo Switch 2 Zelda 40th Anniversary Edition in time for its planned Oct. 29 release. To allow time to fulfill preorders and reshop inventory as needed, the point-of-sale (POS) block will remain in place through at least Friday, Nov. 6. As inventory arrives, orders will be fulfilled based on preorder priority and available inventory.” The Redditor who posted the news shared that some people were able to get the console from Walmart after 8:00am local time, so there is still hope. Target recently updated its Zelda Switch 2 listing to reveal that it will also start taking orders of on November 6, with in stores orders beginning November 5. Clearly, the supply chain delay is impacting other stores, otherwise we likely would have seen a restock take place today, as we initially predicted. We now know that Walmart and Target will be taking online orders, and that Best Buy and Nintendo are holding in-store events on November 5. GameStop is also letting customers pre-order in-store via their website. Despite the news, we’ll still be tracking every retailer with our restock tracker, which provides up-to-the-second information whether something is in stock. If the Zelda Switch 2 does appear – which it might – our followers will still be one of the first to know. Up next: PS5 Pro restock: it’s available again, but you’re paying more than you should Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.
Joe Burrow Sends Strong Message on Bengals Rookie
The Cincinnati Bengals lost tight ends Erick All and Tanner Hudson to injuries in back-to-back games. The two were depth options at tight end, but they combined for 182 snaps this season. So, the team is going to need to lean on the end of roster options to pick up the slack. The name that […] The post Joe Burrow Sends Strong Message on Bengals Rookie appeared first on HEAVY.
Where Belmont Sends Political Donations
Belmont residents gave $414,880 to statewide and federal races in 2024, with major support for Sen. William Brownsberger and Gov. Maura Healey.
Zelda 40th Anniversary Switch 2 Pro Controller restock tracker: we’re watching these retailers
🎮 Nintendo will release a Zelda 40th anniversary Switch 2 Pro Controller on October 29 💰 It costs $99.99, the same as other limited editions 📅 A restock could occur on launch day at Walmart and Best Buy 🚨 Our Zelda Switch 2 Pro Controller restock tracker @mattswider on X will send out an alert when stock appears Walmart: Zelda Pro Controller Best Buy: Zelda Pro Controller Amazon: Zelda Pro Controller Target: Zelda Pro Controller GameStop: Zelda Pro Controller Nintendo is releasing a special limited edition Nintendo Switch 2 Pro Controller to celebrate the 40th anniversary of The Legend of Zelda series. It releases on October 29, 2026, which is when we expect to see a long-awaited restock of the hard-to-find controller. 🚨 We’re tracking Zelda Switch 2 Pro Controller stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 The Switch 2 Pro Controller features the same striking gold and royal emerald color scheme of the Nintendo Switch 2 The Legend of Zelda 40th anniversary edition, and also includes a fun little easter egg on the back: an 8-Bit Link. 🚨 Want the Zelda 40th Anniversary Switch 2 Pro Controller? Drop your email for restock alerts before it sells out. ⤵️ Subscribe This is the same Nintendo Switch 2 Pro Controller we’re used to, aside from the intricate design, but it means you’ll have to pay more as a result. It costs $99.99 instead of the standard $89.99. However, the Pro Controller is the easiest way to play the best Switch 2 games in TV mode. If you’ve been searching for a Zelda 40th Anniversary Switch 2 Pro Controller restock, here’s everything you need to know. Zelda 40th anniversary Switch 2 Pro Controller should restock at these retailers We’ve seen retailers such as Walmart and Best Buy restock items on release day, even when pre-orders have sold out. It’s likely that the Zelda Switch 2 Pro Controller will be up for grabs on October 29, 2026, when the controller and console launches. Demand will be high, and stock could sell out fast. However, we’ll be keeping a close eye on every major retailer, including Target, Amazon, GameStop, and the Nintendo Store and will alert our followers as soon as stock goes live. Why you can trust our Zelda Switch 2 Pro Controller restock tracker We’ve already helped over 400,000 people buy a PS5 when it was in and out of stock during Covid, and we’ve helped our subscribers continue to secure hard-to-find items. The Shortcut followers were some of the first to secure the Switch 2 when it went on sale, and we’ve also helped countless others snag limited edition consoles like the PS5 30th anniversary edition. The Shortcut and Matt Swider on X offer exclusive Zelda 40th anniversary Switch 2 Pro Controller restock updates with up-to-the-second US store inventory checks at the biggest retailers. You’ll receive an instant notification on X (if set to on) as soon as new stock arrives. Up next: Call of Duty: Modern Warfare 4 review roundup: ‘a strong return to form’ Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.
TN Politics: Election Day nears and nude photos enter the chat
State Sen. Brent Taylor says telling the truth about sending unsolicited nude selfies to multiple people makes him honest. Otis Sanford says it should make him disqualified.
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Flooding sends water into Arts District small business shops
Rain on Friday caused flooding in parts of the Arts District, and business owners worked to protect their shops from the water.
DataFi Donation Ceremony at the Ministry of Health-Remarks by ADCM Steve Bremner
DataFi Donation Ceremony at the Ministry of Health Remarks by Acting Deputy Chief of Mission a.i. Steve Bremner (…) I’m pleased to join the Ministry of Public Health and our implementer, Palladium, today to hand over IT equipment including 80 laptops, 300 tablets, and Monitoring and Evaluation reporting tools for CSBII. Good health decisions start with good data. When a health worker in a remote commune notices unusual fever cases, that information must reach district and national teams fast. Every hour counts. Fast, reliable data helps the Ministry detect an outbreak early, send teams where they’re needed, and stop a disease before it spreads. These laptops and tablets will help do exactly that. They’ll strengthen Madagascar’s health information system and disease surveillance so health workers can collect, report, and use data faster and more accurately. This support reflects the America First Global Health Strategy. Under this strategy, the United States works directly with partner governments based on country ownership, shared investment, and accountability for results. Together, we’re strengthening Madagascar’s ability to detect and respond to outbreaks quickly though the MOU signed in December 2025. This work protects Malagasy families and the American people. Today also marks a transition. The Data.FI project is ending, but the work will continue. Palladium will continue to carry these same activities forward through a new project, AFGHS Palladium, under the State Department’s Bureau of Global Health Security and Diplomacy. The new project will put an even stronger focus on results. Mister SG, your ministry’s close collaboration with Data.FI made today possible. I hope you will bring the same commitment to this new project. Together, we can deliver even greater results and speed up the transfer of skills to Ministry teams. Our shared goal is to build the ministry’s capacity to lead, manage, and sustain these systems on its own. That is Madagascar’s path to self-reliance. Equipment alone doesn’t stop an outbreak. People do. To the health workers and data managers who will use these tools: thank you for your dedication. To the Ministry: we count on you to put these devices to work quickly, keep them in good condition, and protect the data they hold. That’s how this investment will deliver results for years to come. The United States stands with the Government of Madagascar. We commend the Ministry of Public Health for its leadership. We look forward to continuing our collaboration through AFGHS Palladium and beyond. Thank you. Misaotra betsaka.
Federal trade officials say a Vancouver-based credit card processor misleads customers into costly contracts
A proposed settlement between the Federal Trade Commission and Riverside Payments, including affiliate Cascade Equipment Leasing, would send $600k to potentially hundreds of Pacific Northwest companies.
Bengals’ Zac Taylor Sends Clear Message Despite Win vs Titans
The Cincinnati Bengals were able to pull off a win against the Tennessee Titans who are struggling as a football team.Though Bengals head coach Zac Taylor was thrilled about the win, there’s also some concern about how Cincy starts football games.“We won. I want a complete game, (and) I want to start the first quarter […] The post Bengals’ Zac Taylor Sends Clear Message Despite Win vs Titans appeared first on HEAVY.
Ravens' Jesse Minter Sends Clear Message About Lamar Jackson's Return
Baltimore Ravens head coach Jesse Minter spoke out with a clear message about Lamar Jackson's return from injury.
Google Sends Major Updates to All of Its Google Home, Nest , Streamer Devices
Google is back this week updating all of its Google Home-related products, from the app and Gemini for Home to the hardware it still supports. On the hardware side of things, we’re seeing updates for the Chromecast with Google TV, Nest WiFi and Nest WiFi Pro, and its Nest and Google Home Speakers. These updates...
Can I trust the polls? And other questions from listeners about the 2026 midterms
Ahead of Election Day, listeners send in questions about whether debates are dead, if polls are reliable for election coverage and how Trump might work with Democrats if they win control of Congress.
‘Praying Both Of My Friends’ – 5-Time Champion Sends Heartfelt Message About Ernie Johnson, Michael Wilson Amid NBA Broadcasters’ Health Issues
Two longtime NBA broadcasters announced in the span of a week that they are stepping back, and both pointed to their health. Ernie Johnson said Oct.
Todd McLellan Sends Blunt Warning After Red Wings’ Stunning Collapse
Todd McLellan calls out the Detroit Red Wings after blowing a two-goal third-period lead in a stunning 5-4 loss to the St. Louis Blues.
Jonathan Taylor Sends Blunt Message Amid Seahawks Trade Rumors
Jonathan Taylor opened up about trade uncertainty and the departures of two Colts teammates, including new Seahawks guard Quenton Nelson. The post Jonathan Taylor Sends Blunt Message Amid Seahawks Trade Rumors appeared first on HEAVY.
Illinois man charged with mailing white powder to members of Congress
Court records show a 37-year-old Illinois man is charged with sending threatening letters to members of Congress containing a white powder, including one with a note reading “HAH enjoy the gift.”.
Stars Trade Pitch Swaps Jason Robertson for Nikita Kucherov
In an original trade pitch from this offer, the Dallas Stars would send Jason Robertson to the Tampa Bay Lightning for Nikita Kucherov.In an absolute stunner, NHL insider Elliotte Friedman reported on Friday night that Kucherov — the reigning Hart Memorial Trophy winner as the NHL’s MVP — will not re-sign with the Lightning ahead […] The post Stars Trade Pitch Swaps Jason Robertson for Nikita Kucherov appeared first on HEAVY.
A golden age of science is coming
It’s almost hard to remember, but just a few years ago, a lot of very smart people thought that science was in terminal decline. Respected researchers were writing papers with titles like “Are Ideas Getting Harder to Find?”, “Papers and patents are becoming less disruptive over time”, and “Slowed canonical progress in large fields of science”. In 1996, science writer John Horgan even published a book called The End Of Science: Facing The Limits Of Knowledge In The Twilight Of The Scientific Age. The fundamental idea was that the Universe only has so many insights to discover, and that we’ve picked the low-hanging fruit. It was the idea that Joseph-Louis Lagrange expressed when he said that “we cannot find more than once a system of the world to establish.” As the big ideas and the simple ideas get mined out, we’re forced to throw ever more brains at the mysteries of nature just to keep scientific progress going at a fraction of its old pace: It looked like science was hitting a wall. Then along came AI. It’s far too early to tell how much AI will eventually speed up the growth of total factor productivity. But already we can see signs of a speedup in science. Anthropic Founder Jack Clark assembled some of the hopeful data points in a recent lecture: [ Dror Poleg@drorpoleg "If you pick different parts of science, you see the same pattern show up: Progress is accelerating, and it has started to accelerate in the last two years." Jack Clark @jackclarkSF I’m speaking at the IMF in an hour about the singularity and why I believe it has begun and the choices we'll need to make. Watch live here: https://t.co/Hj9HzcXx5h 6:08 PM · Oct 18, 2026 · 21.2K Views 2 Replies · 10 Reposts · 123 Likes ](https://x.com/drorpoleg/status/2111882070376980529) Anthropic is accelerating its investment into drug discovery, and is already announcing some impressive preliminary results: [ BioTender@Junioryu136689 BREAKING: Anthropic unveils early results from six Claude-powered drug development collaborations. • 70% shorter CAR-T signaling domain • ~35,000 antibody designs • >10× tighter antibody binding • 89% less batch-record review time Still largely preclinical. Anthropic @AnthropicAI Over the past few months, Anthropic scientists have engaged in deep research partnerships with six organizations developing new medicines. We've also begun drug discovery efforts of our own. In doing so, we’ve learned much more about how Claude can support the many stages of 9:43 PM · Oct 27, 2026 · 11.2K Views 3 Replies · 24 Reposts · 205 Likes ](https://x.com/Junioryu136689/status/2115197821150495150) Claude also appears to be enabling rapid progress toward a treatment for food allergies. OpenAI, meanwhile, announced a possible breakthrough treatment for neurodegenerative disease. Meanwhile, Google Cloud Chief Scientist Pushmeet Kohli has a list of recent scientific advances that have been enabled by its new Gemini model, including breakthroughs in nuclear fusion reactor design, rare disease research, and quantum computing: [ Pushmeet Kohli@pushmeet Gemini 4 Argon is a step change in model performance. In recent weeks, it has had a transformative impact on the Science projects in our team at @GoogleDeepMind and our external collaborators, and helped make a number of remarkable advances across scientific disciplines. 🧵👇 4:47 PM · Oct 13, 2026 · 36.5K Views 8 Replies · 41 Reposts · 497 Likes ](https://x.com/pushmeet/status/2110049807385702623) But as cool as these stories sound, they’re just very minor, preliminary efforts. There are a number of reasons to think that AI is going to propel us into a golden age of scientific discovery. That age might not last forever — AI might still run into diminishing returns eventually. But the next few decades are probably going to be an absolutely amazing time for human science. The number of “effective researchers” is no longer limited The most important input into science is scientists themselves. Until this year, that meant human brains — talented, highly trained human brains. The number of trained human brains could be increased by sending more people to grad school, but only to a point — the smartest people tend to be sent into the hardest research fields first, and if you 10x the number of researchers, the average quality will go down. This constraint was already starting to bite, as Ekerdt and Wu argued in 2024: We argue that a substantial portion of the downward historical trend in U.S. research productivity is a composition effect resulting from self-selection in researcher ability and the dramatic expansion of the research sector…[W]e find that this composition effect has lowered average researcher ability by between 37% and 53%[.] And of course, low fertility was making the problem worse, because fewer children meant fewer people who were able to become future scientists. AI just blows up this constraint completely. If an AI agent can function as an autonomous researcher, there’s no constraint on the number of researchers in the world — you can just build more of them, by building more computer chips and data centers that enable the running of more AI agents. Whether or not massive hordes of agents can collaborate to solve individual problems much faster, increasing the number of agents allows them to tackle many different research questions in parallel. What’s more, these AI “researchers” can be trained incredibly quickly compared to human beings. A human scientist takes decades to train, and more years to reach the frontier of their research field by diligent reading and conversation. This is the “burden of knowledge”, and it’s commonly believed to be one reason ideas have been getting harder to find — by the time human scientists can get up to speed, they’re often so old that their ideas are no longer novel. AI just annihilates this constraint — it can assimilate the entire literature and reach the frontier of research extremely quickly, and it can also tell human scientists where the frontier lies without forcing them to discover that for themselves. It can also pivot to new research directions more easily than humans can. And there’s also a self-reinforcing economic cycle here. Because scientific advances enable higher GDP, they enable more resources to be invested into the creation of yet more electronic “scientists”. Now that doesn’t mean the amount of scientific research goes to infinity — there may still be some essential bottleneck task that human researchers are still needed to perform. There are some indications that AI’s progress on open-ended conceptual research tasks is slower than in other dimensions, and it may be that humans are still needed to provide some of this long-term conceptual thinking. I’d bet against this being true for much longer, but it might be true for a long time. Even in this most “pessimistic” case, though, the amount of effective capital that scientists can use to leverage their work just went up by a lot. AI eliminates the theory bottleneck Science proceeds by an iterative process of theory and experiment. The theory part of that cycle is typically short, but non-trivial — it took a couple of years after the blackbody radiation spectrum was observed for Max Planck to come up with the quantum hypothesis to explain it, and decades longer before quantum theory as we now know it was created. It took about a year for Watson and Crick to figure out the shape of DNA after the requisite data was gathered. AI will basically eliminate the theory bottleneck entirely — or at least shorten the turnaround time between experiment and theory by an order of magnitude. AI is an absolute beast at math. Recently, an OpenAI model solved some of the most important open problems in computer science, math, and theoretical physics, and no one even batted an eyebrow because that sort of triumph is becoming increasingly commonplace. One of those solutions was a proof that the Standard Model of Particle Physics could be mathematically well-defined — a problem that human theorists had so far been unable to tackle. Not all research relies equally on theory, but understanding novel experimental results almost always involves some important component of either mathematical or spatial reasoning. That part of the task has now been made much, much faster. And on top of that, science is now open to a greater number of humans who aren’t naturally good at theorizing. AI can read the whole literature Much of the work of human scientists involves reading and understanding endless amounts of papers and going to endless conferences and seminars. The purpose of that work is to understand the existing scientific literature. Understanding the literature allows scientists to do the following things: Come up with new ideas for hypotheses to test Avoid doing research that someone else has already done Synthesize approaches from different areas or fields AI can reduce this effort to almost zero. Consider this excerpt from OpenAI’s blog post about their new research into neurodegenerative disease: The team divided the analysis among thousands of AI agents powered by GPT‑Rosalind, an approach we call distributed biological reasoning. The agents examined a whole-brain CRISPR atlas…a dataset showing how gene disruptions affect different types of cells across the mouse brain. Each agent investigated a gene disruption, analyzed cellular responses, searched scientific literature, and proposed explanations for the results. Their reports were combined into a reasoning atlas linking genes, cellular effects, relevant publications, and possible biological mechanisms. The research team estimated that comparable human analysis and literature review, conducted one perturbation at a time, would take months to a year. The agents reproduced findings from human analyses while uncovering additional leads. Their assessments of novelty and scientific value also aligned with judgments from blinded human experts. These findings help prioritize further experiments needed to test the proposed biological mechanisms. Some of these insights point to new leads for understanding brain disease. [emphasis mine] This is one case in which parallel work by a large number of agents really does make a huge difference: [ Haider.@haider1 this is actually insane openai deployed thousands of GPT-Rosalind agents to analyze millions of mouse brain cells in 32 minutes, work that could take human researchers months to a year also the agents uncovered new leads for brain diseases like Alzheimer's and Parkinson's OpenAI @OpenAI GPT-Rosalind surfaced a new lead for drug discovery: could restoring cholesterol transport protect neurons from degeneration? DCTN1 is a gene linked to Perry syndrome, a rare neurodegenerative disorder. In mouse-brain data, disrupting it increased expression of genes involved in 2:41 PM · Oct 21, 2026 · 51.5K Views 26 Replies · 95 Reposts · 1.26K Likes ](https://x.com/haider1/status/2112917197903540516) Not only does instantaneous literature review vastly speed up the research process, but it allows AI to make novel conceptual leaps from combining approaches from wildly different fields of research. AI regularly does this in math research, combining results, approaches, and theorems from far-flung places that no human mathematician would have thought to combine. It can do it in science, too. Much of scientific innovation, historically, has been “recombinant” innovation — scientists applying insights from one field to another. With AI, essentially all research is now cross-disciplinary — AI can read not just the literature on a particular subject, but the literature on a million other subjects that might have produced useful techniques or insights for the problem at hand. Superscience So far, all of the factors I’ve listed are ways that AI can speed up science as it’s already done. I’ve basically described how AI can send gigantic hordes of superhumanly fast, superhumanly well-read, superhumanly mathematically gifted researchers to re-accelerate scientific discovery. But it’s also possible that AI will enable types of discovery — and ways of understanding the natural world — that no network of humans, no matter how large or how brilliant it was or how long it had to work, would ever be able to discover. In a post back in July, I wrote about how that might work: What if there are lots of…aspects of the Universe that [are] too complex to understand in terms of simple laws, but not so complex that they just dissolve into unknowable chaos? It’s possible that we can reliably control these complex phenomena with AI, even if we never reduce them to the kind of principles that we can teach a grad student in a textbook… Another way of saying this is that there may be laws of the universe that humans can’t understand but AI can. I call these “cloud laws” — causal regularities that can be exploited by technology, but which are too diffuse and complex for an individual human being to either intuit or communicate… Perhaps social sciences like economics, sociology, and political science obey similarly complex regularities, and AI can help us find them. Perhaps there are physical processes — plasma, or topological materials, or aerial turbulence, etc. — that obey cloud laws instead of chaos?… [H]uman collaboration is bottlenecked — it’s limited by our ability to intuit patterns at an individual level, and to communicate these patterns from one individual to another. AI, being a computer, just doesn’t have this sort of limitation; it can work with vast, diffuse patterns without having to break them into pieces or simplify them in order to compress them into the tiny pipelines of person-to-person explanation… If much of the Universe turns out to be ruled by cloud laws, we could be on the precipice of a scientific renaissance. In order to discover cloud laws, AI will need huge amounts of data about the natural world. AI figured out human speech by assimilating essentially all of the text humans have ever written. If it’s going to figure out hidden patterns in biology, neuroscience, materials science, etc., it’s going to need similarly massive amounts of data from physical instruments. That data will be far, far more than humans — individually or collectively — would be able to parse, label, characterize, or model. But AI was built to do this. If scientists simply build huge arrays of sensors to measure complex phenomena like the brain, the cell, the economy, etc., they may be able to feed this flood of data to AI directly and bypass human cognitive intermediation entirely. AI would then learn about the world directly, and it might learn things that humans never could. This “superscience”, if you want to call it that, would actually go beyond the kind of science humans have done heretofore. Many of the technologies it yielded would be beyond human comprehension — indistinguishable from magic. But to the AIs, they would make perfect scientific sense. In any case, it seems clear that the scientific slowdown that threatened human progress will now be delayed — at least for a while. Unless humans have somehow found most of the actual exploitable regularities in our Universe, we’re about to enter a new golden age of science. Subscribe Share
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