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Politics, Policy, and the enduring Drivers of Texas Economic Growth
Texas Border Business I try (often unsuccessfully) to avoid politics whenever possible, but it has a tendency to frequently collide with economics. This past week, I was in all parts of Texas interacting with thousands of people. I heard some proclaiming the end of the “Texas Miracle,” while others heralded the dawn of a new […]
Heichal HaTorah Talmidim Experiment in the Science Lab
This past week, Heichal HaTorah’s ninth-grade biology students learned how to use indicators to test the pH levels of common household solutions. Students observed a wide range of colors as natural plant-based pigments (anthocyanins) in red cabbage juice reacted with acids and bases in everyday substances. Students made predictions and determined whether a substance was […]
Ethiopia: Violence in the north is pushing health system to the brink, WHO chief warns
The head of the World Health Organization (WHO) called on Monday for greater protection for civilians caught in conflict in northern Ethiopia following deadly drone strikes this past weekend.
Three new iPad models are reportedly launching early next year, here's what's coming
After debuting the refreshed iPad mini with OLED this past week, Apple still has more in the pipeline for the...
DeForest Area Public Library News
Phew! We made it past the Family Halloween Party a couple of weeks ago, and past the Haunted Library this past weekend. And it isn’t even Halloween yet!
Witches and Warlocks revel in downtown Oscoda during ninth annual celebration
OSCODA – Witches took over downtown Oscoda this past weekend, during the ninth annual Witches, Warlocks & Steampunk Weekend.
‘More than just math and science’: LeTourneau University hosts prospective engineering, aviation students - Longview News-Journal
Aspiring engineers and pilots from 18 states traveled to Longview this past weekend to learn about LeTourneau University’s engineering and aviation programs. On Saturday, high school seniors from across the […]
Cheerleading earns multiple bids to UCA Nationals
The North Allegheny cheerleading program turned in an impressive performance this past weekend at the UCA Ohio Regional, with multiple teams earning bids to the UCA National High School Cheerleading Championship in Orlando, Florida. The Tigers’ JV Traditional, Varsity Traditional and Varsity Game Day teams all secured bids to the national championship, highlighting a successful… More »
Georgia football rises in AP Poll rankings during bye week
Georgia Bulldogs rise in the latest AP Top 25 rankings despite being on a bye week this past weekend.
2026 Bowl Projections After Week Seven
Hello everyone, and welcome back to our weekly picks of who's in the playoffs and all the bowl games. This past week was circled on calendars since the schedules were revealed, with several top-25 matchups. However, it's doubtful anyone could have predicted what we saw, where five of the top seven teams in the AP …
'Office Space' star Richard Riehle dies at 78
Actor Richard Riehle arrives at the premiere of New Line Cinema's 'A Very Harold & Kumar 3D Christmas' at Grauman's Chinese Theatre on November 2, 2011 in Hollywood, California. (Jason Merritt/Getty Images)Richard Riehle, known for his role in the 1999 film Office Space, has died. He was 78.A statement shared by Artists & Representatives and Wright Entertainment, Inc. announced Riehle's passing on Monday, writing, "Our industry has lost an exceptional talent, and our community has lost a truly wonderful man.""We are deeply saddened to confirm the passing of our beloved client, Richard Riehle, this past weekend," the statement said. "A remarkable actor whose career in theater, film, and television spanned nearly five decades and more than 400 projects, Richard leaves behind an extraordinary legacy."The statement continued, "Beyond his immense talent, he will be remembered for his genuine goodness, boundless kindness, and unwavering generosity, particularly toward emerging actors and filmmakers, whom he encouraged and supported at every opportunity."Born on May 12, 1948, Riehle starred in many television series and films over the years.Notable projects include Casino, The Man from Earth and Deuce Bigalow: Male Gigolo.He got his start as an actor at the University of Notre Dame, where he was involved in the University Theatre and starred in several stage productions. He went on to earn a Master of Fine Arts in acting and directing from the University of Minnesota.While he's played characters that have an "average Joe" presence, he always made the most of his brief screen time.Some roles that he is remembered for include The Quartermaster in Glory, the train guard in The Fugitive, Reverend Scroggins in Fried Green Tomatoes and Bill Cozbi in Bridesmaids.On television, he starred as Principal Ed Rooney in the 1990 series Ferris Bueller and as grandfather Walt Finnerty in the early 2000s sitcom, Grounded For Life.In 2023, he also played Warden Reynolds in Barry.Riehle is survived by his wife, Jane Latham, and their four children.Copyright © 2026, ABC Audio. All rights reserved.
Report card from Nebraska's late-night loss to Oregon
Nebraska came up short yet again this past week, dropping a 17-14 after-dark clash in Oregon due to Nebraska’s inability to perform consistently.
Mountain West Connection Players of the Week: Week 7
Who were the top performers from this past weekend?
WATCH: Indiana tackle Carter Smith previews Ohio State
Indiana football starting left tackle Carter Smith addressed the media on Tuesday afternoon ahead of Indiana’s huge matchup against Ohio State this Saturday at Memorial Stadium in Bloomington. Smith addressed the Hoosiers’ matchup against Nebraska this past weekend, the environment at Memorial Stadium, the strengths of the Ohio state defense, growing up in Ohio just […]
Daldrop Opens for Business in Southern Oswego County
$10 Million Facility in the L. Michael Treadwell Oswego County Industrial Park marks the largest expansion outside of Germany in the company’s 73-year history By Stefan Yablonski [caption id=attachment_11076 align=alignright width=450] Daldrop SBB CEO Jens Daldrop addresses attendees at the 2025 groundbreaking for the project. Daldrop also chairs the advisory board of Germany-based Daldrop Group.[/caption] A new era of cleanroom technology is underway in Central New York. The Daldrop Group’s advanced manufacturing facility and U.S. headquarters is physically built within the L. Michael Treadwell Oswego County Industrial Park. This industrial park is located in the town of Schroeppel. It marks the largest expansion outside of Germany in the company’s 73-year history. Daldrop SBB is based in Neckartailfingen, Germany. It is a global supplier of cleanroom technology, primarily to the pharmaceutical industry. It designs and builds advanced cleanroom environments for the pharmaceutical, biotechnology and medical technology industries. It nvested $10 million in the new project. “We broke ground in 2025; we were under construction all winter. We just opened this spring, early spring,” said Benjamin Morrow, operations manager and control. The company consolidated sites in Salina and DeWitt into the industrial park in Schroeppel, Morrow added. “The next move here is to maximize every square inch of this facility and then we are already looking at the expansion. So, it is more capital investment on equipment — definitely higher-end automation in additional equipment so we can produce more components and then to support the ever-growing base in North America,” Morrow continued. “We are the headquarters for service, maintenance and spare parts. So as Daldrop has more and more installations, they need more and more service, maintenance and spare parts. So that will come out of this facility as well — it already is.” “As a global leader in GMP (global manufacturing support) pharmaceutical cleanrooms for decades, I am very proud to bring manufacturing jobs to Upstate New York,” said Mike Sullivan, president of Daldrop US operations. Key to choosing Southern Oswego County [caption id=attachment_11077 align=alignright width=450] Daldrop SBB at the L. Michael Treadwell Oswego County Industrial Park when the company announced the start of construction.[/caption] Sullivan said that the selection of the Schroeppel industrial park was mainly due to the help of Operation Oswego County and two people in the organization. “Prior to being purchased by Daldrop International from the Stuttgart region of Germany, Vince Bongio was a founding partner in SBB Inc. as well as our head of engineering. We based out of Syracuse due to Vince’s skills in HVAC and the manufacturing capabilities found in Syracuse,” said Sullivan. Bongio moved to Syracuse from California in the 1970s to work in Carrier’s Industrial Division of Large-Scale Petrochemical Refrigeration. Next, he advanced to General Electric’s TV Tube Plant where he got into cleanrooms ,leading to his role of head of engineering for Clestra Cleanrooms where he met Sullivan, their New England distributor. “Vince Bongio is a phenomenal engineer. Formerly of Carrier, he grew up in California and went to Cal Poly,” Sullivan explained. “Carrier hired him right out of college and he moved to Syracuse. He is the reason we are in Syracuse today. He is retiring this year. We are very proud and his legacy is having brought Daldrop to Syracuse.” In 2000, Sullivan, Bazinet, Bongio Inc (SBB) was formed with engineering and manufacturing, based in Syracuse, and sales and construction based in Massachusetts as it is today. “SBB Inc. started in Syracuse. I had a design–build contracting firm out of Massachusetts that was primarily doing all the new technologies coming out of MIT,” Sullivan said. “I started a manufacturing side. A big thing for cleanrooms is the HVAC. Most cleanroom suppliers are architecturally focused people. The strength in Syracuse is HVAC. So, SBB developed with me running sales and construction out of Massachusetts and manufacturing out of Syracuse.” “Daldrop wanted to have a relationship in the States and of those who approached us, they were the only ones who really understood HVAC. So, we were the right fit for them. We did a joint venture focused out of Massachusetts from 2012 to 2018 leveraging their technologies,” Sullivan explained. “The commitment was if we brought their product to the States, we would do that if they built it here. “The pieces that had to be in place to make the investment, they wanted to acquire us, we were great with that. If you looked at business recommendations the general guidance was to build in a low labor area — something like North Carolina — but Syracuse had a strong background in HVAC and we chose Syracuse and Oswego County to be our headquarters in the States. So, it is built off of history, technology and the existing supply chain — bringing jobs back to the area.” During the initial discussions with Daldrop about coming to the U.S., SBB agreed to sell under the conditions Daldrop would manufacture in the U.S. There are many areas that offer incentives and economic packages, but the strength of HVAC expertise and skilled manufacturing was a big part of the discussions for site selection. Coming home [caption id=attachment_11078 align=alignright width=451] Construction moves forward in March at the L. Michael Treadwell Oswego County Industrial Park.[/caption] The second key person to building in Oswego County is Ben Morrow, Sullivan added. “Ben has been working with Daldrop SBB for more than 12 years and has advanced to COO of manufacturing and engineering. Ben grew up in Phoenix, so building a factory for the Germany company in Phoenix is a strong success for both his community and the appreciation of Ben’s skills as a team leader,” Sullivan said. “I went to high school in Phoenix. So, this is like full circle for me. It’s a small world,” Morrow said. “I hadn’t been back to Phoenix since graduation. This is one of the properties that John Trimble of C&S, he is the former president of C&S, he just retired, suggested. He and I were very good personal friends. John was from Mexico and I was from Phoenix. We knew each other from high school. And the architect of this building, Ed Smart of smartDESIGN Architecture in Batavia — I went to high school with him. So, this was a project that’s full circle a coming home kind of thing. The three of us knew each other — kind of like it was meant to be. Very serendipitous.” Schroeppel was one option for Daldrop to consider; the original intent was just to get a warehouse to store some product, he added. The facility is Daldrop’s largest outside of their native country. Total payroll at the facility will be approximately $2.4 million once fully staffed. “Here is 32,000 square feet and we plan to expand and put in an additional 10,000 square feet,” Morrow said. “We have 17.5 acres. We can put at least three more facilities here, just on this property. The master plan submitted for the current building is the first of possible three buildings on the campus.” “If we can find the right people and advance the production according to the plan, we should be able to grow for the next decade. One of the first jobs we filled was our new HR manager, with a primary focus posting and filling new positions,” Sullivan said. Stop the exodus, start hiring [caption id=attachment_11080 align=alignright width=452] Principals at the local Daldrop SBB headquarters, from left: Ben Morrow, Mike Sullivan and Jens Daldrop.[/caption] “I have been coming to Syracuse for 30 years. One of the things I had a hard time watching was the exodus of factories. One of the toughest things is to watch it with my partners’ kids who had to move away for jobs. It is important for us to give opportunity where people’s kids don’t have to leave the area to get work,” Sullivan said. “My responsibility is to find people who have skill sets that want to work and then I have to build opportunity for that work to happen. “After years of watching companies and Vince’s three sons all move out of the areas to get jobs, it is important to us to provide opportunities for the Syracuse region and help grow our company. We have been hiring for our new factory and will continue for the next few years.” “We are hiring and will continue to hire. Currently we have about 19 on staff right now,” Morrow said. “We expect to grow that by about 10 to 15 in the next 12 to 18 months or so. We are at 19 currently — one in the wings. It’s been great being able to hire locally. All these folks that we’ve been hiring, they all live within a few miles from here.” “We hired someone this past week (end of August). She grew up in the area, raised a family and is working down in Florida. She just took a job with us so she can move back and be with her family. We will be moving her back and she should be starting in October. We are very happy to see this happen,” Sullivan said. “I feel strongly about having a spot for the kids to not have to move out of the area. It is better to have people moving into the area.” Currently, Daldrop SBB has openings for finance manager, COO of construction and delivery, as well as mechanical, electrical designers and Revit modelers, construction managers, commissioning agents and many other skills that are needed. Along with Daldrop’s reputation in life science cleanrooms, there is a strong history in semiconductor, electronics, glass, photonics, aerospace and other markets. This may be helpful with any new technologies building in the market such as the Micron expansion and the support network, Sullivan said. “We acquired this property and closed on it two months before any announcement from Micron. It is serendipitous that they’re right down the street from us,” Morrow added. “Everybody started thinking ‘you guys are supporting Micron.’ We were here first. That is not a goal of ours. We may or may not … they are talking to us; it is an opportunity.” The long run [caption id=attachment_11079 align=alignright width=450] Benjamin Morrow, operations manager and control at Daldlrop, speaks during a recent ribbon-cutting event in Schroeppel.[/caption] “Long term, we will expand the Phoenix facility,” Sullivan said. “We built our facility with a campus approach. Sustainability is big. We designed our rooms to be more sustainable. Our building has no gas lines for heat. We put geothermal wells in the ground. We put heat pumps in for heating and cooling out of those wells and we put a large layer of solar panels up on the roof. We worked with National Grid for metering. Our building is a high efficiency model. We upgraded all the instillation and the glass filtering. So, it is a very green building. We will have a very minimal carbon footprint. It also adheres to LEED (Leadership in Energy and Environmental Design) construction standards.” “We are a bunch of HVAC engineers. We did a large scale geothermal and spent the money up front because we knew it made sense in the business sense in the environmental sense and sustainability,” Morrow said. “We have insulated metal panels on walls and roof; we are an envelope from the exterior.” Daldrop, as a global player, has a strong culture of sustainability that is found in all its products including the new facility. The building has been designed with (sixteen) 400-foot deep geothermal wells, high efficiency construction methods, approximately 70 kilowatt solar photovoltaic panels, electric vehicle chargers and 26% recycled content. “Daldrop thinks of long-term investing,” Sullivan said. “On the roof, photovoltaic panels supplement our power. Over half the energy that I use is coming from the sun. We have chargers up front for employee electric vehicles. This place is built to last. This slab that we are walking on, normal buildings are four inches, some go to six inches, we are nine inches all the way through — except where the heavy equipment is — that is 10 to 12 inches thick, solid concrete. It allows us to reconfigure for whatever type of equipment we want to bring in,” Morrow said. “We are authorized by Underwriters Laboratory to self-certify so we don’t need to have an inspector come out and recertify. We get audited often, but we certify our own electronics. The control system in this building is rather high-end. Our thermostat in every room is zoned, independent. We analyze the data; incorporate it with our solar panels.” “There is a lot of competition for people to work. It’s not just about how much salary they are going to make — it’s about the work environment, the ability for stability. We want to make sure our employees have the best environment to work in,” Morrow added. Similarities “One of the reasons I believe why Daldrop chose this area, Phoenix in particular, is because it is a village, a river-based village. Neckartailfingen in Germany where Daldrop is based is also a river-based village, manufacturing community. So, there is a lot of similarities — that smalltown feel,” Morrow said. “We have a lot of connections through multiple employees that lead back to Carrier, also. Everything came together, the timing everything.” “We are thankful for all the economic development support. Everyone has been helping make this happen. So, keep it up, it is working, that is all I got to say, Sullivan said. “If you look at historical industrial manufacturing, this region has skills that have been un-utilized. The northern industrial region has a lot of skills that if we can tap before they go away, we can leverage them. That is what we are trying to do. You’d be surprised at the supply chain left behind from Carrier — that supply chain is still there.” “Operation Oswego County has been fantastic,” Morrow added. “I can’t say enough good things about that group.” What Is Cleanroom Technology Cleanroom technology is a system of specialized engineering, filtration and operational controls used to maintain an extremely low concentration of airborne particles, microbes and chemical vapors. How It Works • Air Filtration: Uses HEPA or ULPA filters to remove 99.97% of tiny particles down to 0.3 microns. • Airflow Control: Directs air in a steady, unidirectional (laminar) or filtered turbulent pattern to push dust away from work areas. • Environmental Regulation: Maintains precise control over temperature, humidity and positive air pressure to block outside air leaks. • Specialized Attire: Requires personnel to wear full-body garments (“bunny suits”), gloves and masks to stop human shedding
Packers' Jordan Love Moves Up NFL List Despite Inconsistent Performance
The Green Bay Packers got a huge win this past weekend.
Bucco Discusses 4-Point Affordability Plan on ‘Minding Your Business’
On this past weekend’s “Minding Your Business” on News 12+, Senate Republican Leader Anthony Bucco discussed his 4-point affordability plan to help New
Downtown Cape Girardeau business owners credit increased police presence for a safer weekend
Downtown business owners say this past weekend was noticeably calmer after Cape Girardeau police increased their presence with more walking officers, police vehicles and patrolmen on the ground.
Week 5 Nebraska volleyball grades
Nebraska volleyball swept Missouri, Rutgers and Ohio State this past week and proved themselves once again. The players themselves such as Bergen Reilly, Andi Jackson and Harper Murray, have shown that they are efficient and persistent on the court and will continue to succeed.
2026 Bowl Projections After Week Three
Hello everyone and welcome back to our latest bowl projections here at Last Word On College Football. This past weekend was certainly an interesting one of course headed by the big one down in Oxford. The Rebels won out over LSU, and that shook up our rankings a little. In addition, another playoff team stumbled …
This Week in Politics: Rollbacks and Restrictions
The Trump administration made several consequential announcements this past week, from rescinding environmental protections to supposedly banning several news agencies from the White House. The United States Environmental Protection Agency (EPA), which sets national regulations to protect the environment and public health, announced on Monday, Sept. 14, that it will remove regulations on greenhouse gas...
Miguel Vargas named AL Player of the Week
The heart of the White Sox kept his club afloat this past week, and was rewarded with leaguewide honors
Letters to the Editor: Deer season brings ticks, and November brings politics
The following are Letters to the Editor published in the print edition of the Star-Observer this past week.
Georgia football's AP Poll ranking after Arkansas win
Georgia remains ranked second in the AP Top 25 Poll despite a dominant 45-17 win over Arkansas this past weekend.
New releases from Blancpain, Czapek, Grand Seiko and more
This past week has been one for the ages. Rolex announces an annual calendar carrying an official nickname for the first time, Blancpain releases one of the smallest mechanical movements to date, and Grand Seiko brings back Arabic numerals after 25 years. There’s plenty more too, spanning other all sort of styles and budgets with … Continued
Game Time Thread: Juventus vs. NEC Nijmegen
Juventus look to begin their Europa League campaign in a much better way than they saw things played out this past weekend domestically.
Lion Tales: Buffalo
In September 2015, Penn State was coming off an embarrassing loss to Temple in Philadelphia, a game that you saw mentioned a lot in this past week. Well, just like this year, the Nittany Lions came back home to take on MAC opponent Buffalo for a Noon kick at Beaver Stadium. That’s the subject of […]
How did the Rojiblanca academy fare at the weekend?
La Cantera Rojiblanca had plenty of action this past weekend in Matchdays 8 and 9 of the 2026 Apertura, against Atlas and Pumas, respectively. Here’s how our young players fared in their matches.It ...
"This past week was great. It's always nice to visit …
"This past week was great. It's always nice to visit …
Mets Minor League Players of the Week: Week Twenty-Four
What minor league players put up the best numbers this past week, September 1st to September 6th?
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Christian Watson Issues Clear Harrison Smith Message Before Vikings Game
The Minnesota Vikings defense received a major boost this past weekend as Harrison Smith returned on a one-year contract. Moreover, the reported contract is worth $12.25 million, with a maximum value of $16.25 million, per NFL Network’s Ian Rapoport and Mike Garafolo.Minnesota will have its QB on defense relaying what defensive coordinator Brian Flores wants the […] The post Christian Watson Issues Clear Harrison Smith Message Before Vikings Game appeared first on HEAVY.
Jackrabbits fueled by missed opportunities
BROOKINGS, S.D. (KELO) — The SDSU Jackrabbits marched into Evanston, Illinois this past weekend to take on Northwestern, and despite many trips inside Wildcat territory the big play never came. The Jacks made seven total trips inside the Northwestern 20-yard line but only came away with a touchdown one time. Head Coach Dan Jackson says […]
Kenilworth Recap: New Staff, Football Victory, Police Safety Update & More
KENILWORTH, NJ - Did you miss this past week
Old friends, fierce rivals play at 95th New York State horseshoe championship in Camden
Nestled beneath the trees in southern Camden, the game of horseshoes is alive and well at the Pine Grove Horseshoe Club on Route 13. The club hosted the 95th annual New York State Horseshoe Pitcher's State Championship Tournament this past weekend, where pitchers from all across the state gathered to find the best of the best.
The Blood of Dawnwalker has sold 1 million copies worldwide
The Blood of Dawnwalker launched this past week.
Los Angeles Dodgers Announce Will Smith News Before Cardinals Game
After winning their series against the Detroit Tigers this past weekend, the Los Angeles Dodgers are returning home to face the St. Louis Cardinals. With the calendar turning to September, that means MLB rosters have officially expanded. And the Dodgers are returning a key piece to their offense in the form of Will Smith, who […] The post Los Angeles Dodgers Announce Will Smith News Before Cardinals Game appeared first on HEAVY.
Casper's Outback Steakhouse closes permanently after nearly three decades of business
CASPER, Wyo. –– The Casper area Outback Steakhouse located in Evansville closed over this past weekend without warning. Its listing at the Outback website
Giants Sign Ex-Saints Quarterback After Surprise Retirement
The New York Giants had a surprise retirement this past weekend, when veteran cornerback Sam Webb abruptly retired just one day after the preseason opener against the Minnesota Vikings.To replace Webb’s spot on the 90-man roster, the Giants are signing veteran quarterback Jake Haener, per NFL Network’s Mike Garafolo, who was drafted by the New […] The post Giants Sign Ex-Saints Quarterback After Surprise Retirement appeared first on HEAVY.
Yankees legend says goodbye as he battles health issues: ‘Thank you & God Bless’
Former MLB pitcher Tommy John, a four-time All-Star, missed New York Yankees' Old-Timers' Day this past weekend.
I Just Had My Mind Blown By A Car Museum In The Middle Of Nowhere Built By A Scrap-Metal Magnate
Having lived in Detroit, LA, and Bavaria, and having a brother who lives in Hong Kong, I’ve been lucky enough to see some of the greatest car museums/collections this world has to offer. This past weekend, while on vacation with my family in Iowa, I saw one that surprised me and that I feel compelled […]
Tommy John, ex-Yankees pitcher and namesake of career-saving surgery, says goodbye amid health issues
The lefty didn’t attend Old-Timers’ Day at Yankee Stadium this past weekend, but instead penned a note thanking everyone who made his career possible.
Robbers target businesses on Chicago's Southwest Side
Chicago police issued a business alert this past weekend, warning store employees to be vigilant as detectives investigate a pair of robberies.
Selling the Dream of SpaceX Was the Easy Part. Now Elon Musk Has to Hang On.
SpaceX’s $300 billion swing in market value this past week put Musk back in grind mode, having to execute on highflying promises made in the lead-up to the biggest IPO ever.
Microsoft released Windows 11 KB5102117 update for OS recovery
New dynamic update for Windows 11 versions 25H2 and 24H2 were released by Microsoft this past week.
A-List celebrities show up for 40/40 Club at Fanatics Fest
Some of the biggest names in sports, music, and fashion, converged in New York City for Fanatics Fest over this past weekend. While many took part in all of
Glenwood South businesses frustrated over weekend chaos: 'Do not care'
Several small business owners on or around Glenwood South are frustrated by the chaos that erupted this past weekend.
Governor Moore Announced Energy Assistance To Lower Utility Bills for 200,000 Maryland Households, Wrote On How To Improve Young Men’s Mental Health, Applauded SCOTUS Decision To Uphold Birthright Citizenship, And A Local Farmer Said ‘Gov. Moore Takes Action For Farmers’
This past week, Governor Wes Moore announced energy assistance programs to help lower utility bills for 200,000 Maryland households, published an opinion piece on how to improve young men’s mental health, applauded the SCOTUS decision to uphold birthright citizenship, and a local farmer applauded his work to secure a USDA Secretarial Disaster Declaration. Governor Moore […]
This week in politics: How Schuylkill County’s legislators voted
The PA House of Representatives was in session this past week and passed 16 bills. Let’s take a look at how Schuylkill County’s legislators voted on notable pieces of legislation. PA General Assembly HB 2084, PA Promise – Improving Co…
Beyond red and blue: Pew says Americans fall into one of nine political groups
The Pew Research Center’s new “political typology” was published this past week and was based on surveys from last fall. Most Americans fall within a “politically messy center,” while smaller groups of partisan and politically active voters…
What’s Next For Belal?
UFC Vegas 118 went down this past weekend (Sat., June 6, 2026) inside Meta Apex in Las Vegas, Nevada, leaving several fighters feeling the post-fight blues. Among them was Santiago Luna, who was choked out by Bryce Mitchell in the third and final round (see it again here). And Junior Tafa, who was knocked out […]
AMC Entertainment Records Its Highest Domestic and Global May Attendance Since 2019
AMC Entertainment welcomed more than 4.2 million moviegoers to its U.S. AMC Theatres and internationally at its ODEON Cinemas this past weekend, from Thursday through Sunday. Combined with totals from prior weeks, AMC saw 25.5 million guests at their domestic and global locations in the month of May, making the month the highest-attended month of […]
AMC Entertainment Records Its Highest Domestic and Global May Attendance Since 2019
LEAWOOD, Kan., June 01, 2026--AMC Entertainment (NYSE: AMC), the largest theatrical exhibitor in the United States and the world, welcomed more than 4.2 million moviegoers to its U.S. AMC Theatres and internationally at its ODEON Cinemas this past weekend, from Thursday through Sunday. After yet another strong weekend at the box office in May, both domestically and globally AMC Entertainment received 25.5 million guests at our theatres, recording the highest-attended month of May since 2019.
Longtime retailer closes, entertainment center expansion coming soon at Wind Creek outlets
General Store, offering a wide array of gifts, greeting cards, holiday decor and more, closed this past weekend at The Outlets at Wind Creek Bethlehem.
Chicago Cubs update: Ethan Roberts, Jacob Webb, Hoby Milner
This past week was mostly “down.”
Morning Sports: May 26, 2026
Sheridan County HS Track and Field: Sheridan County High School Track and Field teams brought home 4 trophies, 3 of which said state champions this past weekend. The Sheridan boys 3-peated in Class 4A and made it 5 of the last 6. The Big Horn boys 4-peated in Class 2A, while the Big Horn girls […]
Ohio State basketball Big Ten opponents announced for 2026-27
This past week, the Big Ten announced the Ohio State basketball opponents for the 2026-27 conference season.
Kansas baseball drops out of top 10 in USA TODAY Sports Coaches Poll
KU baseball didn’t find much joy in its results this past week, losing all four games it played. So, it dropped in the USA TODAY Sports Coaches Poll.
Letters to the Editor: Hope for Earth, the DMV and national politics
The following are letters published in the Star-Observer's print edition this past week.
How it happened last time … and some lessons
It happened once before and Brian Lewis chronicled it this past week.
Herald News top photos of the week: Spring sports and more
Herald News photographer Colin Furze cast his eye on the Fall River area this past week, delivering some unusual sights.
Fermilab celebrates 2026 quantum science program graduates
This past weekend, a new group of high school students graduated from the Saturday Morning Quantum program. Hosted by Fermilab, the course allows students to engage directly with lab quantum scientists and engineers while exploring core topics in quantum science.
USD students take care of mental health on Fresh Check Day
This past week, students at the University of South Dakota called on people to check their own mental health and check in on their friends and family.
Michigan State baseball earns B1G series win over Washington
Michigan State earned a massive Big Ten series win over Washington this past weekend.
Housing waitlist, new entertainment venue, more: Cape Cod Times top stories
Catch up on the four most-read stories on the Cape Cod Times website from this past week.
Leah Halton-Pope named Democratic candidate for 141st Assembly District
It comes after Crystal Peoples-Stokes announced this past week she would not seek reelection.
Computer Science Students Compete in Software Hackathon - University of the Ozarks
A group of University of the Ozarks computer science students took part this past weekend in HogHacks, a 24-hour collegiate hackathon held at the University of Arkansas. Hosted by the Association for Computing Machinery (ACM) at the U of A, the event is an overnight software engineering competition among area college students that takes place […]
LG killed its smartphones 5 years ago, but the ‘Rollable’ feels more real than ever [Video]
This past weekend was the 5-year anniversary of the death of LG’s smartphone business, and yet, we’re just now seeing...
Man accused of exposing himself to minors at business
A Cape Girardeau man was arrested for allegedly exposing himself to children this past week.
Why Vince Vaughn thinks late-night TV 'stopped being funny'
Vince Vaughn shared his hot take on the state of late-night television during an appearance on Theo Von's "This Past Weekend" podcast.
See Kansas basketball’s ranking in USA TODAY Sports Coaches Poll
Kansas basketball had a pair of highly-ranked matchups this past week, beating Houston at home and losing at Arizona. Where do the Jayhawks rank now?
Two snowplows destroyed following massive blaze at a local business in Lakeville
The destroyed vehicles had each been used extensively during the blizzard this past week.
Is J.J.McCarthy’s Status with the Vikings in Doubt?
One of the more provocative rumors circulating around the NFL Combine this past week is that the Minnesota Vikings have soured on J.J. McCarthy and may even be pursuing an exit strategy with the former first-round pick. Tony Pauline reports that the Vikings are “quietly pursuing an exit strategy” for McCarthy and that a source […]
Atrium Health's too-suburban ER
Atrium Health plans were revealed this past week for a new freestanding emergency room at North Davidson Street and Belmont Avenue.
Why the ‘AI scare trade’ might not be done
A sell-off rippled through software, real estate and trucking stocks this past week as investors worried artificial intelligence could upend some industries — and analysts say the white-knuckle drops might not be over yet.
Health chief Kennedy says he’s no germaphobe, recalls snorting cocaine off toilet seats
The Kennedy scion divulged his old drug habits on comedian Theo Von’s podcast “This Past Weekend.
Will Commodity Sports Last?
If you wanted to bet on the Super Bowl this past weekend, you had options. You may have bet with a friend. If you live in a state where it’s legal, you could have gone to a casino or used a casino’s app. Or, starting last year, you could have entered into an event contract […]
Is Kansas basketball in top 10 of USA TODAY Sports Coaches Poll?
Kansas basketball picked up a pair of wins this past week. Here’s what that’s meant for KU in the top 25 of the USA TODAY Sports Coaches Poll.
Zambia bishops instruct clergy and faithful to stay out of partisan politics
“The Church is not and must never be a mouthpiece for any political party or candidate,” the Zambian bishops stated. Read more in this roundup of world news that you may have missed this past week.
The latest release of Jeffrey Epstein files: Who is mentioned and what they are saying in response
Here is a look at some of the notable names in the latest release of files from the U.S. Justice Department pertaining to Jeffrey Epstein. The list includes politicians, entertainment figures, business leaders and Royal Family members, with some releasing statements this past weekend about their interactions with the late accused child sex trafficker.
Analysis: Trump’s team almost never backs down from its false claims. This past week has been different
From the start, this has been a say-anything presidential administration.
How scientists predict big winter storms : Short Wave
This past weekend, Winter Storm Fern struck the States. Sleet, snow and ice battered Americans all the way from New Mexico to New York. Scientists predicted its arrival in mid-January, and in anticipation of the storm, more than 20 state governors issued emergency declarations. But how did scientists know so much, so early, about the approaching storm? NPR climate reporter Rebecca Hersher says it has to do with our weather models… and the data we put into them. Which begs the question: Will we continue to invest in them?Interested in more science behind the weather? Check out our episodes on better storm prediction in the tropics and how the Santa Ana winds impact the fire season this time of year. Have a question we haven’t covered? Email us at shortwave@npr.org. We’d love to consider it for a future episode! Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.This episode was produced by Hannah Chinn. It was edited by our showrunner Rebecca Ramirez. Tyler Jones and Rebecca Hersher checked the facts. The audio engineer was Robert Rodriguez. News clips were from CBS Boston, Fox Weather, Fox 4 Dallas-Fort Worth, and PBS Newshour.
2025 PFWA All-AFC team: Full roster
The PFWA announced all-NFL and all-conference teams this past week. This is the roster for the AFC.
Broncos need to run the ball effectively vs. the Bills
The Buffalo Bills have one major weakness that the Denver Broncos NEED to take advantage of this Saturday, and it is their run defense. The Jacksonville Jaguars were running all over the Bills’ defense this past weekend, but for whatever reason, they did not lean into it. Veteran running back Trevor Etienne Jr. only had […]
Health officials warn of potential measles exposure on Amtrak, BWI Airport shuttles
A person with an infectious case of measles passed through Maryland this past week, potentially exposing passengers on Amtrak trains and shuttle buses serving BWI Airport, the Maryland Department o…
Samsung Weekly: Galaxy S27 Camera, Galaxy S26 Launch Date, One UI 8.5 Beta 3, 60W charging, CES 2026, AI Profit and more
Samsung is keeping its preparations steady for the Galaxy S26 series launch with new certifications and leaks surfacing online, and a fresh input indicates that the Galaxy S27 series will bring an even bigger camera upgrade to date. This past week marked the celebration of the tech industry via the CES 2026, and Samsung revealed […]
Martin, Diaz officially signed
Two relievers were officially added to the 40 man roster this past week
Morning Sports: December 1, 2025
Sheridan Hawks Junior Hockey: The Sheridan Hawks Junior Hockey Team won both ends of their home and home series this past weekend vs. Gillette. Friday’s score on the road was 4-1 and Saturday’s score at home was 3-1. Sheridan will play another home and home series this weekend vs. Rapid City.